Analysis of Histopathological Findings in Hysterectomy Specimens of Women with Menorrhagia across Various Age Groups

Heavy menstrual bleeding significantly impairs the quality of life of many healthy women. Sixty percent of these patients develop Anemia. Perception of heavy menstrual bleeding is subjective, and management usually depends upon what symptoms. Surgical options include conservative surgery (uterine resection or ablation) and hysterectomy. Menorrhagia is usually associated with benign pathologies and only rarely with malignancy. Aim: Aim of this study to identify the different pathological condition in hysterectomy specimen of patients that present with history of menorrhagia. Material and Method: Descriptive study was done on 73 hysterectomy specimens in pathology department of tertiary care center of histology section. Patents with history of menorrhagia and abnormal uterine bleeding included in study. The specimens were grossed by the pathologists in pathology and processed, stained with H &E and examined microscopically. Result: In this study the age group of patients was 31 to 70 years of age. 47.9% (n=35) presented with complaints of menorrhagia between 41-50 years of age group. 41% (n=30) were from 31-40 years age group. Out of 73 cases, 38% cases (n=28) showed leiomyomas, followed by adenomyosis in 13.6% cases (n=10), 20% cases (n=15) showed dual pathology consisting of both leiomyomas and adenomyosis. Maximum no. of lesion showed was leiomyomas (n=12) in 41-50 years of age group then (n=12) in 31-40 years of age group. Conclusion: In conclusion, the analysis of histological patterns in menorrhagia cases revealed leiomyomas as the most common pathology, followed by adenomyosis. Coexistence of both leiomyomas and adenomyosis was also observed. These findings highlight the significance of a comprehensive histopathological evaluation in the management of menorrhagia, enabling tailored treatment approaches based on individual patient needs. Further research is required to expand our knowledge of the underlying mechanisms and refine diagnostic and therapeutic strategies for this common gynecological concern.

(English)

Heavy menstrual bleeding significantly impairs the quality of life of many healthy women. Sixty percent of these patients develop Anemia. Perception of heavy menstrual bleeding is subjective, and management usually depends upon what symptoms. Surgical options include conservative surgery (uterine resection or ablation) and hysterectomy. Menorrhagia is usually associated with benign pathologies and only rarely with malignancy. Aim: Aim of this study to identify the different pathological condition in hysterectomy specimen of patients that present with history of menorrhagia. Material and Method: Descriptive study was done on 73 hysterectomy specimens in pathology department of tertiary care center of histology section. Patents with history of menorrhagia and abnormal uterine bleeding included in study. The specimens were grossed by the pathologists in pathology and processed, stained with H &E and examined microscopically. Result: In this study the age group of patients was 31 to 70 years of age. 47.9% (n=35) presented with complaints of menorrhagia between 41-50 years of age group. 41% (n=30) were from 31-40 years age group. Out of 73 cases, 38% cases (n=28) showed leiomyomas, followed by adenomyosis in 13.6% cases (n=10), 20% cases (n=15) showed dual pathology consisting of both leiomyomas and adenomyosis. Maximum no. of lesion showed was leiomyomas (n=12) in 41-50 years of age group then (n=12) in 31-40 years of age group. Conclusion: In conclusion, the analysis of histological patterns in menorrhagia cases revealed leiomyomas as the most common pathology, followed by adenomyosis. Coexistence of both leiomyomas and adenomyosis was also observed. These findings highlight the significance of a comprehensive histopathological evaluation in the management of menorrhagia, enabling tailored treatment approaches based on individual patient needs. Further research is required to expand our knowledge of the underlying mechanisms and refine diagnostic and therapeutic strategies for this common gynecological concern. Files IJPCR,Vol15,Issue5,Article88.pdf Files (519.9 kB) | Name | Size | Download all | |---|---|---| | md5:04fcacbc9601ba64e18019a5f3c08157 | 519.9 kB | Preview Download | Additional details Dates - Accepted - 2023-04-30 Software - Repository URL - https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue5,Article88.pdf - Development Status - Active

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