The study of the reproductive outcome after myomectomy in infertile patients with uterine myoma.

Objective: The purpose of this study is to evaluate the reproductive outcome after myomectomy in infertile patients with uterine myoma. Methods: During the period from January 1993 to December 2002, 55 infertile women with uterine myoma underwent abdominal myomectomy at Department of Obstetrics and Gynecology. Results: Pregnancy occurred in 32 women and pregnancy rate was 58.2%. Parity, the number, type, and location of myoma, the opening of endometrial cavity during operation and the presence of endometriosis were not significantly different between the pregnant and nonpregnant group. But the mean age and duration of infertility were significantly low in pregnant group. The 24-month cumulative probability of conception was 84.4% and the spontaneous abortion rate after myomectomy was 28.1%. Conclusion: Our results suggest a benefit of myomectomy in infertile patients. Factors affecting the pregnancy rate after surgery in these patients are the age of the patient and the duration of infertility. Therefore, it is important that we should explain these factors to patients carefully before surgery.