The Role of DNAJB9 in the Pathogenesis of Triple Negative Breast Cancer: Case Report
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Abstract
KEY CLINICAL MESSAGE: Previous studies showed that DNAJB9 is protective against metastatic TNBC. Our patient had complete pathologic response of nonmetastatic TNBC after 3 cycles of chemotherapy but developed DNAJB9-related fibrillary glomerulonephritis. Was DNAJB9 pivotal for this remarkable TNBC response, and if so, could it be a potential biomarker or target looking forward?
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- europepmc
- last seen: 2026-05-20T01:45:00.602351+00:00