Coexistence of Haemorrhoids, Monkeypox, and Condyloma Acuminatum: A Rare Case Report

Monkeypox is an infectious disease caused by the monkeypox virus, while condyloma acuminata is a common sexually transmitted infection caused by human papillomavirus (HPV). Hemorrhoids result from venous congestion and swelling of the rectal or anal vascular plexus. This case report describes a patient presenting with perianal discomfort, ultimately diagnosed with concurrent monkeypox, condyloma acuminata, and hemorrhoids. Initially, the monkeypox rash—localized to the perianal region—was misdiagnosed as condyloma acuminata due to overlapping clinical features, leading to a delayed diagnosis of monkeypox. We detail the diagnostic journey, from initial misdiagnosis to definitive identification, and discuss the therapeutic management of this complex presentation. This case underscores the importance of differentiating monkeypox from other infectious perianal lesions and provides insights into perioperative considerations for monkeypox-infected patients.