Feasibility and Safety of Day-Case Laparoscopic Myomectomy: The First UK Case Series of 20 Consecutive Patients with Zero Complications

Objectives: To evaluate the safety and feasibility of day-case laparoscopic myomectomy in the UK, and to present the first published UK case series from the North Middlesex Endometriosis Centre (NMEC). A Standard Operating Procedure (SOP) and a novel patient surgical passport were implemented to optimise patient education and perioperative care. Design: Retrospective case series. Setting: North Middlesex Endometriosis Centre (NMEC), London, UK. Population; Twenty consecutive women undergoing planned day-case laparoscopic myomectomy. Methods: Between January 2023 and July 2025, 20 women underwent day-case laparoscopic myomectomy at NMEC, performed by a single experienced laparoscopic surgeon. All patients had preoperative pelvic MRI for fibroid localisation and exclusion of suspicious features. Surgery was performed using a standardised four-port technique, with fibroid removal by power morcellation inside a containment bag. Patients were managed under an SOP and received a surgical passport detailing every stage of their surgical journey. Outcomes included operative time, blood loss, complications, discharge timing, and readmissions. Main outcome measures: Operative duration, estimated blood loss, discharge interval, perioperative complications, readmissions, and histological results. Results: Median age was 34 years (range 28–42). Median operative time was 95 minutes (range 75–125), and median blood loss 120 mL (range 70–200). All patients were discharged within 8 hours. No intraoperative or postoperative complications occurred, and no readmissions were required within 30 days. No conversions to laparotomy occurred. Histology confirmed benign leiomyomata in all cases. Patient feedback highlighted high satisfaction with the surgical passport and early discharge. Conclusion: This is the first UK case series of day-case laparoscopic myomectomy. With MRI screening, contained morcellation, and structured perioperative pathways, including SOPs and a surgical passport, NMEC has demonstrated that same-day laparoscopic myomectomy is safe and feasible. These findings provide a model for potential national adoption within the NHS.