Pathology of Breast Cancer: from Classic Concepts to Molecular Pathology and Pathogenesis

Ilze Štrumfa, Andrejs Vanags, Arnis Āboliņš, Jānis Gardovskis
In: Acta Chirurgica Latviensis · 2012 · vol. 12(1) , pp. 59–66 · doi:10.2478/v10163-012-0012-x · W2075362731
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This review discusses classic breast cancer pathology alongside molecular subtypes, novel prognostic markers, and molecular pathogenesis to inform personalized surgical treatment planning.

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Abstract

Summary Breast cancer has high incidence and still significant mortality. Due to the widespread application and efficacy of surgery in breast cancer treatment, the surgeon has a crucial role in the treatment planning. Taking into account the tendency to personalized cancer care and the heterogeneity of breast cancer, the surgeon has to be aware about the prognostic and predictive characteristics of breast cancer. We discuss here the classaic pathology of breast cancer along with molecular subtypes, novel prognostic markers and molecular pathogenesis.

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last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK