Oxalate Nephropathy in a Patient with COVID-19- Infection: Causation or Association

Abstract The pandemic due to Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV2) has led to significant morbidity and mortality over the last two years. Although lungs are the primarily involved organ with infection due to COVID-19, there have been rising rates of COVID-19 related kidney disease. Kidney injury among patients with COVID-19 can present in multiple ways, and different pathophysiologic mechanisms have been suggested. We describe a case of an elderly woman who developed acute kidney injury secondary to oxalate nephropathy in the setting of severe COVID-19 infection and needed hemodialysis. Our case illustrates that calcium oxalate crystal deposition in the kidney (oxalate nephropathy) could be one of the possible pathophysiologic mechanisms of renal dysfunction in the setting of COVID-19.