Retrospective study of botulinum neurotoxin for hemifacial spasm: experience over 25 years

ABSTRACT Introduction Hemifacial spasm (HFS) is a not uncommon, debilitating movement disorder. This retrospective study examines 25 years of experience with Botulinum neurotoxin (BoNT) injections for HFS in Malaysia. Objective To assess BoNT’s long-term effectiveness in treating HFS in a private practice. Methods Data from 35 patients, including demographics, treatment outcomes, and complications, were collected from a private clinic over 25 years. Results BoNT demonstrated a decreasing dose trend over time, with extended treatment intervals. Complications were rare and transient, with high patient retention. Conclusion BoNT is a safe and effective long-term HFS treatment, enhancing accessibility in private practice, complementing public healthcare services.