Use of stock DICOM data of fibular bone for CAD-CAM design in facial reconstruction by free fibula flap | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Use of stock DICOM data of fibular bone for CAD-CAM design in facial reconstruction by free fibula flap Massimiliano Gilli, Antonio Bimonte, Umberto Committeri, Gabriele Monarchi, and 7 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7482022/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 31 Jan, 2026 Read the published version in European Journal of Plastic Surgery → Version 1 posted 7 You are reading this latest preprint version Abstract Background : The free fibula flap (FFF) is a cornerstone in facial skeletal reconstruction, but its harvest may be challenging in 5–10% of cases due to concerns over vascularization. While lower limb CT angiography is widely used to assess vascular patency, it involves ionizing radiation and iodinated contrast, posing risks, especially for patients with renal insufficiency or allergies. This study investigates the use of stock fibula models, derived from average anatomical measurements, as a reliable alternative to patient-specific fibulae for surgical planning, thereby eliminating the need for CT angiography. The safeness off fibula harvesting is guaranteed by US color Doppler. Methods: A total of 40 fibulas (20 male, 20 female) were analyzed using DICOM data obtained from standard CT scans. Data segmentation and measurement were performed by an open source softwere (3Dslicer). Results: Statistical analysis showed significant differences in fibular dimensions between genders (p < 0.00001), with minimal variability (CV Width M: 8.66%, CV Thickness M: 10.43%, CV Width F: 10.88%, CV Thickness F: 14.43%), confirming the suitability of stock models for accurate reconstructive plans. Importantly, bypassing CT angiography eliminates radiation exposure and the administration of iodinated contrast, reducing patient risks. Conclusion: The results suggest that stock fibula models, based on population averages, provide an effective and safe solution for facial reconstruction, ensuring high surgical precision without the need for CT angiography or contrast agents. Free fibula flap Reconstructive surgery facial reconstruction fibula harvesting Figures Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Introduction Since its introduction in the 1970s [ 1 ], the free fibula flap (FFF) has played a central role in reconstruction of the facial skeleton. It is a highly versatile flap and remains the most widely used option for osseous reconstruction of the facial region due to the ample availability of bone and the adequate length of its vascular pedicle [ 2 , 3 ]. However, in a non-negligible percentage of cases (5–10%), the flap cannot be harvested safely due to concerns regarding sufficient vascularization of the foot [ 4 ]. For this reason, various techniques have been described in the literature to assess the course and patency of the peroneal and tibial vessels and therefore a safe harvest of the flap [ 4 ]. Currently, the most commonly used examination is lower limb CT angiography, which offers the advantage of providing highly detailed DICOM data, useful not only for vascular evaluation but also for morphological analysis of the fibula [ 4 ]. Since the 2000s, CAD-CAM technologies have been increasingly adopted in surgical practice, enabling the virtual planning and real-time 3D printing of anatomical models and cutting guides based on DICOM files. These innovations have improved surgical precision and reduced operative time [ 5 ]. However, CT angiography also presents some drawbacks, including exposure to ionizing radiation and the need for contrast medium administration. The aim of this study is to propose a valid alternative to CT angiography for acquiring DICOM data of the fibula, while still enabling virtual planning and the production of 3D models and cutting guides for surgical procedures. Material and methods A total of 20 fibulae from male patients and 20 fibulae from female patients were included in this anatomical study. DICOM data were acquired through lower limb CT scans performed at the Azienda Ospedaliera of Perugia. Patients included in the study ranged from 18 to 70 years of age and underwent CT imaging for various clinical indications. Patients with current or previous fibular fractures, as well as those with osteo-deforming diseases, were excluded. Two separate databases were created based on sex, due to the evident differences in bone size and morphology. The distal and proximal 7 cm of each fibula were excluded from the analysis, as these segments are not usable in reconstructive surgery. Fibula segmentation and morphometric measurements were performed using the open-source software 3D-Slicer. Width and thickness were measured in the midpoint of the fibula. The DICOM data of the selected CT angiography were uploaded to the 3D slicer program as shown in figure 1. (Figure 1) The data were segmented and cleaned to remove the other anatomical parts that are not of interest for this study as shown in figure 2. (Figure 2) Finally, after obtaining the segment of the fibula stripped of the 7 cm distal and proximal, measurements were taken. (Figure 3) Statistical analysis Morphometric parameters of male and female fibulae (length, width, thickness and volume) were firstly assessed with the Kolmogorov-Smirnov test, which confirmed normal data distribution in both groups. Subsequently, intergroup differences between male and female fibulae measurements were analyzed using the Student’s t-test for independent samples. Among the measured parameters, width and thickness were identified as the most representative variables for the design of a stock fibular anatomical model and corresponding cutting guide. For these two parameters the coefficient of variation (CV) was calculated to quantify the intra-group variability. Representative specimens for male and female cohorts were selected using a closest-to-mean approach, based on the Euclidean distance between individual fibulae morphometric parameters (width and thickness) and their corresponding group means values. The specimen with the shortest Euclidean distance was the one designated as a stock model. To assess the accuracy and the potential clinical applicability of the selected stock models, the mean absolute error (MAE) was computed from the differences in both parameters between the representative specimen and the remaining fibulae, and the clinical coverage (CC) was calculated as the percentage of fibulae within a maximum tolerance of ± 2mm for both parameters. Results (Table 1) For the male group the mean length of the fibula was 24.67 ± 0.70 cm (SD 1,59 cm) with a maximum of 27.06 cm and a minimum of 22.49 cm. The mean width was 12.47 ± 0.47 mm (SD 1.08 mm) with a maximum of 14.72 mm and a minimum of 10.24 mm. The mean thickness was 10.64 ± 0.49 mm (SD 1,11 mm) with a maximum of 12.50 mm and a minimum of 8.32 mm. The mean volume was 3.29 ± 0.25 cm 3 (SD 0.58 cm 3 ) with a maximum of 4.19 cm 3 and a minimum of 2.21 cm 3 . (Table 2) For the female group the mean length of the fibula was 22.26 ± 0.65 cm (SD 1.49 cm) with a maximum of 24.97 cm and a minimum of 19.97 cm. The mean width was 10.85 ± 0.52 mm (SD 1.18 mm) with a maximum of 12.83 mm and a minimum of 8.73 mm. The mean thickness was 8.59 ± 0.54 mm (SD 1,24 mm) with a maximum of 10.17 mm and a minimum of 6.31 mm. The mean volume was 2.12 ± 0.27 cm 3 (SD 0.62 cm 3 ) with a maximum of 3.19 cm 3 and a minimum of 1.11 cm 3 . Statistically significant differences between males and females were observed for all measured parameters: Length male vs femaleà p-value<0,00001 Width male vs femaleà p-value=0,000027 Thickness male vs femaleà p-value<0,00001 Volume male vs femaleà p-value<0,00001 These findings confirm the need of developing two distinct stock models for male and female fibulae. Width and thickness were selected as the most suitable for the design of a fibula stock model. For these two parameters the variability was considered sufficiently low to assess their reliability in both groups: CV of width in malesà 8,66% CV of thickness in malesà 10,43% CV of width in femalesà 10,88% CV of thickness in femalesà 14,43% (Figure 4, Table 3) The selected specimen for males had a width of 12.20 mm and a thickness of 10.60 mm with a Euclidean distance from the mean of 0.27 mm. The mean Euclidean distance in males was 1.28 mm. (Figure 5, Table 3) The selected specimen for females had a width of 10.99 mm and a thickness of 8.48 mm with a Euclidean distance from the mean of 0.18 mm. The mean Euclidean distance in females was 1.38 mm. (Table 4) The Mean Absolut Error (MAE) between the selected stock model and remaining fibulae was consistently below ± 2mm of tolerance reported in scientific literature in both groups for width and thickness: MAE of width in malesà ± 0.89 mm MAE of thickness malesà ± 0.96 mm MAE of width femalesà ± 0.98 mm MAE of thickness femalesà ± 1.07 mm The overall Clinical Coverage (CC) was of 89.47%; in two cases (5.26%) both parameters exceeded the ± 2 mm tolerance, while in another two cases (5.26%) only one parameter was outside the tolerance range. Discussion Since the early use of the fibula in reconstructions, the necessity for a reliable examination to assess the presence and patency of the peroneal and tibial vessels in the leg has been recognized. Several alternatives have been proposed in the literature, among which CT angiography of the lower limbs has emerged as the gold standard [ 6 ]. This examination allows for an effective evaluation of the tibial and peroneal vessels and also provides DICOM data of the fibula, enabling preoperative assessments and planning directly on the bone that will subsequently be harvested for reconstruction. CT angiography proves particularly useful in preventing vascular complications in the foot; however, it remains a procedure that requires the infusion of iodinated contrast medium [ 2 ]. As is well established, iodinated contrast is nephrotoxic and cannot be administered to patients with renal insufficiency (GFR < 45 ml/min), unless the risks of further impairing renal function are deemed acceptable [ 7 ]. Furthermore, there is the issue of allergic reactions, with some patients experiencing severe reactions that necessitate the suspension of the examination and significant delays in the diagnostic and therapeutic process [ 8 ]. Given that many patients undergoing such interventions are affected by malignant neoplasms, the time factor is of paramount importance. Additionally, like any CT examination, CT angiography involves the use of ionizing radiation. In light of these considerations, color Doppler ultrasound has been increasingly utilized as a preoperative examination to evaluate the vascularization of the leg [ 9 – 11 ]. While this method is employed in the literature, it has never surpassed CT angiography, primarily due to the inability to study and acquire bone data for the customized planning of reconstructions. The inability to obtain DICOM data of the fibula represents the principal limitation to the validation of this intervention using color Doppler ultrasound. To address this issue, a fibula database (one for males and one for females) has been created in order to ascertain whether the differences between various fibulae are sufficiently large to preclude segmentation and customized planning, even when using a stock peroneal bone. The analysis excluded the distal and proximal 7 cm segments of the fibula, as these regions are necessary for ensuring the stability of the knee and ankle joints and are therefore not utilized in the reconstruction [ 3 ]. The fibula selected as a model for both males and females was chosen based on width and thickness, selecting the fibula that deviated least from these values. The statistical difference between males and females suggest the need for two different databases. Length was not considered a parameter for selecting the stock fibula, as it does not influence the dimensions of the peroneal segments actually used in reconstruction. Instead, the minimum measured lengths (22 cm for males and 20 cm for females) were considered as the hypothetical maximum usable bone length for planning purposes. The bone volume of the fibula is a parameter that can be useful in reconstruction planning. By comparing the volume of the resected mandibular/maxillary bone with the estimated volume of the fibula, one can confirm the reconstruction plan or consider shifting to other reconstructive grafts, such as the iliac crest, should the expected volumetric differences prove too significant. The principal critique of this technique is that it creates a customized plan, which hinges on precision as its key advantage, using a fibula that is not the patient's own, thus introducing a degree of approximation. The objective of this study is to estimate the extent of this approximation and determine whether it remains within acceptable limits. Literature evidence suggests that this degree of approximation is indeed acceptable, as similar reconstructions of the facial skeleton, considered successful, also carry a margin of error when compared to the digital plan, typically within 2 mm [ 12 – 14 ]. In the operating room, there is inevitably some discrepancy between the surgical plan and the actual procedure, just as the use of a stock fibula requires a degree of tolerance compared to the patient's own fibula. Considering the statistical results obtained; a MAE of approximately 1 mm, which is below the tolerance threshold of 2mm, and a clinical coverage of 89.47%; it can be concluded that the variability of the fibula is low enough and therefore does not compromise the reconstructive outcome. The critical challenges of this method are primarily related to reconstructive plans for large defects and the use of customized plates, where the mandibular contouring with titanium must accommodate the fibula within the plate itself. In the clinical practice of this center, the philosophy is to minimize the titanium content in the plate to the minimum required to support the load-bearing forces of the reconstructed segment [ 15 – 16 ]. This reconstructive philosophy aligns well with the proposed technique. It is acknowledged that for more extreme cases, where the volume of bone required for reconstruction is close to the limits of these parameters, it may be safer to perform at least a CT scan of the lower limb to utilize the patient's own DICOM data. This would allow the avoidance of iodinated contrast and reduce the amount of radiation administered to the patient. Conclusion The choice of an examination to assess the vascularization of the foot in the case of a fibula free flap reconstruction is crucial. Color Doppler ultrasound allows for a reliable assessment of the foot's vascularization avoiding IR and contrast medium. However, this does not preclude the possibility of performing a customized reconstruction using stock fibula data that represent the general population. The differences between the various fibulae are minimal and, in our opinion, can be considered acceptable. Declarations The authors declare that no funds, grants, or other support were received during the preparation of this manuscript. The authors have no relevant financial or non-financial interests to disclose. All authors contributed to the study conception and design. All authors read and approved the final manuscript. This study was performed in line with the principles of the Declaration of Helsinki. Human Ethics and Consent to participate declarations: not applicable. The S. Maria della Misericordia Hospital Research Ethics Committee (CER Umbria) has confirmed that no ethical approval is required. Informed consent was obtained from all individual participants included in the study. Clinical trial number: not applicable Author Contribution Massimiliano Gilli study ideaAntonio Bimonte statisticUmberto Committeri data segmentationGabriele Monarchi english revisorAngela Rosa Caso reference Federica Sacchi data collectionMaria Elisa Giovannoni data collectionGiuseppe Consorti surgeonFrancesco Giovacchini surgeonValeria Mitro table creatorAntonio Tullio supervision References Taylor, G. I., Miller, G. D., & Ham, F. J. (1975). The free vascularized bone graft. A clinical extension of microvascular techniques. Plast Reconstr Surg 55(5), 533–544. Gilli, M., Committeri, U., Monarchi, G. et al. Mean Arterial Pressure (MAP) influence on free flap oxygen saturation (StO2) measured by near-infrared spectroscopy (2025). Eur J Plast Surg 48, 29 https://doi.org/10.1007/s00238-025-02288-4 Giovacchini F, Monarchi G, Mitro V et al (2021) Maxilla reconstruction using a free fibula flap and virtual planning. Chirurgia 34(5):227–231. Gryseleyn, R., Schlund, M., Pigache, P., Wojcik, T., Raoul, G., & Ferri, J. (2017). Influence of preoperative imaging on fibula free flap harvesting. J Stomatol Oral Maxillofac Surg, 118(5), 265–270. https://doi.org/10.1016/j.jormas.2017.05.002 Giovacchini F, Gilli M, Mitro V et al (2021) Rapid prototyping: applications in oral and maxillofacial surgery. J Oral Med Oral Surg 27:11 Karanas, Y. L., Antony, A., Rubin, G., & Chang, J. (2004). Preoperative CT angiography for free fibula transfer. Microsurgery, 24(2), 125–127. https://doi.org/10.1002/micr.20009 Nyman, U., Ahlkvist, J., Aspelin, P., Brismar, T., Frid, A., Hellström, M., Liss, P., Sterner, G., Leander, P., & Contrast Media Committee of the Swedish Society of Uroradiology and in collaboration with the Swedish Society of Nephrology (GS) and the Swedish Society of Diabetology (AF) (2018). Preventing contrast medium-induced acute kidney injury: Side-by-side comparison of Swedish-ESUR guidelines. Eur Radiol, 28(12), 5384–5395. https://doi.org/10.1007/s00330-018-5678-6. Byrne, A., Macdonald, D. B., Kirkpatrick, I. D. C., Pham, M., Green, C. R., Copaescu, A. M., McInnes, M. D. F., Ling, L., Ellis, A., & Costa, A. F. (2025). CAR/CSACI Practice Guidance for Contrast Media Hypersensitivity. Can Assoc Radiol J, 76(3), 400–416. https://doi.org/10.1177/08465371241311253. Futran, N. D., Stack, B. C., Jr, & Zaccardi, M. J. (1998). Preoperative color flow Doppler imaging for fibula free tissue transfers. Ann Vasc Surg, 12(5), 445–450. https://doi.org/10.1007/s100169900182. Smith, R. B., Thomas, R. D., & Funk, G. F. (2003). Fibula free flaps: the role of angiography in patients with abnormal results on preoperative color flow Doppler studies. Arch Otolaryngol Head Neck Surg, 129(7), 712–715. https://doi.org/10.1001/archotol.129.7.712. Whitley, S. P., Sandhu, S., & Cardozo, A. (2004). Preoperative vascular assessment of the lower limb for harvest of a fibular flap: the views of vascular surgeons in the United Kingdom. Br J Oral Maxillofac Surg, 42(4), 307–310. https://doi.org/10.1016/j.bjoms.2004.02.019. Dell'Aversana Orabona, G., Abbate, V., Maglitto, F., Bonavolontà, P., Salzano, G., Romano, A., Reccia, A., Committeri, U., Iaconetta, G., & Califano, L. (2018). Low-cost, self-made CAD/CAM-guiding system for mandibular reconstruction. Surg Oncol, 27(2), 200–207. https://doi.org/10.1016/j.suronc.2018.03.007. Tarsitano, A., Battaglia, S., Ricotta, F., Bortolani, B., Cercenelli, L., Marcelli, E., Cipriani, R., & Marchetti, C. (2018). Accuracy of CAD/CAM mandibular reconstruction: A three-dimensional, fully virtual outcome evaluation method. J Craniomaxillofac Surg, 46(7), 1121–1125. https://doi.org/10.1016/j.jcms.2018.05.010. Sweed, A. H., Bolzoni, A. R., Kadubiec, A., Beltramini, G. A., Cherchi, A., & Baj, A. (2020). Factors influencing CAD/CAM accuracy in fibula free flap mandibular reconstruction. Acta Otorhinolaryngol Ital, 40(2), 138–143. https://doi.org/10.14639/0392-100X-N0400. Gilli, M., Giovacchini, F., Mitro, V., Sacchi, F., Committeri, U., Caso, A.R., Monarchi, G., & Tullio, A. (2025). Near-Infrared Spectroscopy Sensors, Which Type to Choose and How to Fix it in Cranio- and Maxillo-facial Reconstructive Surgery: Tip and Tricks. J Maxillofac Oral Surg. Nobis, C. P., Lutz, R., Weber, M., Preidl, R., Goetze, E., Frohwitter, G., & Kesting, M. R. (2022). Performance of different osteosynthesis materials in microvascular fibula free flap reconstruction. Br J Oral Maxillofac Surg, 60(5), 623–628. https://doi.org/10.1016/j.bjoms.2021.10.013 Tables Tab.1 shows the data of the 20 fibulae examined for the male population. The distal and proximal 7 cm segments, which are unusable for reconstruction, have already been excluded from the data reported. Each fibula is described by its length, width, thickness, and volume. The respective means, standard deviations and confidence intervals (95%) are reported. Male patients Lenght (cm) Width (mm) Thickness (mm) Volume (cm 3 ) 26.01 12.69 10.46 3.45 25.38 11.55 9.55 2.81 26.66 12.01 11.02 3.52 24.08 13.00 11.48 3.59 25.93 12.89 10.85 3.62 25.95 11.68 9.28 2.81 24.58 10.78 8.32 2.24 26.00 12.53 10.37 3.37 24.25 11.67 9.29 2.62 22.50 12.23 11.60 3.19 22.99 13.68 11.39 3.58 27.06 12.70 11.46 3.93 26.09 11.66 9.46 2.87 26.74 12.74 11.52 3.92 22.59 10.24 9.59 2.21 23.97 13.99 12.50 4.19 22.49 12.20 10.60 2.98 22.59 14.72 11.39 3.78 24.52 13,77 12.29 4.14 22.98 12.68 10.40 3.03 24.67 12.47 10.64 3.29 Mean 1.59 1.08 1.11 0.58 Sd 0.70 0.47 0.49 0.25 C.I. Tab. 2 shows the data of the 20 fibulae examined for the female population. The distal and proximal 7 cm segments, which are unusable for reconstruction, have already been excluded from the data reported. Each fibula is described by its length, width, thickness, and volume. The respective means, standard deviations and confidence intervals (95%) characterizing the population under study are also reported. Female patients Length (cm) Width (mm) Thickness (mm) Volume (cm 3 ) 23.73 11.79 9.14 2.56 21.38 10.74 8.06 1.85 24.52 12.83 10.17 3.19 21.33 10.38 8.88 1.96 22.88 11.77 9.08 2.44 22.71 11.03 9.94 2.48 21.32 10.38 8.13 1.79 22.82 11.85 9.94 2.68 20.35 9.67 7.02 1.38 22.24 10.98 8.38 2.04 24.97 11.94 9.16 2.73 21.66 10.66 8.42 1.94 23.20 12.03 10.16 2.83 19.97 8.94 6.31 1.12 20.86 9.42 7.22 1.41 22.33 11.25 9.46 2.37 21.11 9.22 7.35 1.43 24.08 10.99 8.48 2.24 23.68 12.31 10.11 2.91 19.97 8.73 6.39 1.11 22.26 10.85 8.59 2.12 Mean 1.49 1.18 1.24 0.62 Sd 0.65 0.52 0.54 0.27 C.I. Tab. 3 shows width and thickness of male and female fibulae and their Euclideand distance from the respective groups mean values. For each group, the fibula with the shortest Euclidean distance from the mean has been highlighted in green. Male Female Width (mm) Thickness (mm) Euclidean distance (mm) Width (mm) Thickness (mm) Euclidean distance (mm) 12.69 10.46 0.28 11.79 9.14 1.09 11.55 9.55 1.43 10.74 8.06 0.54 12.01 11.02 0.60 12.83 10.17 2.53 13.00 11,48 0.99 10.38 8.88 0.55 12.89 10.85 0.47 11.77 9.08 1.04 11.68 9.28 1.57 11.03 9.94 1.36 10.78 8.32 2.87 10.38 8.13 0.66 12.53 10.37 0.28 11.85 9.94 1.68 11.67 9.29 1.57 9.67 7.02 1.96 12.23 11.60 0.99 10.98 8.38 0.25 13.68 11.39 1.42 11.94 9.16 1.23 12.70 11.46 0.85 10.66 8.42 0.25 11.66 9.46 1.43 12.03 10.16 1.96 12.74 11.52 0.92 8.94 6.31 2.97 10.24 9.59 2.46 9.42 7.22 1.98 13.99 12.50 2.40 11.25 9.46 0.96 12.20 10.60 0.27 9.22 7.35 2.05 14.72 11.39 2.37 10.99 8.48 0.18 13.77 12.29 2.10 12.31 10.11 2.11 12.68 10.40 0.32 8.73 6.39 3.06 Tab.4 shows the differences for width and thickness in both groups between individual fibulae and the one selected as a stock model (highlighted in green). Fibulae that exceeded the 2mm tolerance in at least one of the two parameters have been highlighted in red. Male Female Diff. Stock width (mm) Diff. Stock thickness (mm) Diff. Stock width (mm) Diff. Stock thickness (mm) -0.49 0.14 -0.80 -0.66 0.65 1.05 0.25 0.42 0.19 -0.42 -1.84 -1.69 -0.80 -0.88 0.61 -0.40 -0.69 -0.25 -0.78 -0.60 0.52 1.32 -0.04 -1.46 1.42 2.28 0.61 0.35 -0.33 0.23 -0.86 -1.46 0.53 1.31 1.32 1.46 -0.03 -1.00 0.01 0.10 -1.48 -0.79 -0.95 -0.68 -0.50 -0.86 0.33 0.06 0.54 1.14 -1.04 -1.68 -0.54 -0.92 2.05 2.17 1.96 1.01 1.57 1.26 -1.79 -1.90 -0.26 -0.98 0 0 1.77 1.13 -2.52 -0.79 0 0 -1.57 -1.69 -1.32 -1.63 -0.48 0.20 2.26 2.09 Additional Declarations No competing interests reported. Cite Share Download PDF Status: Published Journal Publication published 31 Jan, 2026 Read the published version in European Journal of Plastic Surgery → Version 1 posted Editorial decision: Revision requested 14 Sep, 2025 Reviews received at journal 12 Sep, 2025 Reviewers agreed at journal 12 Sep, 2025 Reviewers invited by journal 09 Sep, 2025 Editor assigned by journal 01 Sep, 2025 Submission checks completed at journal 01 Sep, 2025 First submitted to journal 28 Aug, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-7482022","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":514815811,"identity":"d4a0819f-5087-4864-ae2b-e2832099ce92","order_by":0,"name":"Massimiliano 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Siena","correspondingAuthor":false,"prefix":"","firstName":"Antonio","middleName":"","lastName":"Bimonte","suffix":""},{"id":514815815,"identity":"a3a7756b-77a7-4336-be8f-025bdbdea73e","order_by":2,"name":"Umberto Committeri","email":"","orcid":"","institution":"Azienda Ospedaliera di Terni","correspondingAuthor":false,"prefix":"","firstName":"Umberto","middleName":"","lastName":"Committeri","suffix":""},{"id":514815816,"identity":"7a3e81c4-2b0a-4a3d-9360-f383a84f92c6","order_by":3,"name":"Gabriele Monarchi","email":"","orcid":"","institution":"Università degli studi di Siena","correspondingAuthor":false,"prefix":"","firstName":"Gabriele","middleName":"","lastName":"Monarchi","suffix":""},{"id":514815817,"identity":"1764aa56-6405-4f10-b221-dc1d86f63f35","order_by":4,"name":"Angela Rosa Caso","email":"","orcid":"","institution":"Azienda Ospedaliera di Perugia","correspondingAuthor":false,"prefix":"","firstName":"Angela","middleName":"Rosa","lastName":"Caso","suffix":""},{"id":514815818,"identity":"c7ea17de-ee02-4c93-b1b1-309b2c80fdfe","order_by":5,"name":"Federica Sacchi","email":"","orcid":"","institution":"Università degli studi di Siena","correspondingAuthor":false,"prefix":"","firstName":"Federica","middleName":"","lastName":"Sacchi","suffix":""},{"id":514815819,"identity":"37f392b8-00c9-4577-8d14-4e980537befd","order_by":6,"name":"Maria Elisa Giovannoni","email":"","orcid":"","institution":"Università degli studi di Siena","correspondingAuthor":false,"prefix":"","firstName":"Maria","middleName":"Elisa","lastName":"Giovannoni","suffix":""},{"id":514815820,"identity":"5a9f8b1a-d568-478d-95a8-58201eb17b12","order_by":7,"name":"Giuseppe Consorti","email":"","orcid":"","institution":"Azienda Ospedaliero Universitaria Ospedali Riuniti","correspondingAuthor":false,"prefix":"","firstName":"Giuseppe","middleName":"","lastName":"Consorti","suffix":""},{"id":514815821,"identity":"5dc61b1e-39de-4f1d-afb4-6492892dc95f","order_by":8,"name":"Francesco Giovacchini","email":"","orcid":"","institution":"Azienda Ospedaliera di Perugia","correspondingAuthor":false,"prefix":"","firstName":"Francesco","middleName":"","lastName":"Giovacchini","suffix":""},{"id":514815822,"identity":"8de933d2-9f19-4398-b73e-3c75efdcdb6d","order_by":9,"name":"Valeria Mitro","email":"","orcid":"","institution":"Azienda Ospedaliera di Perugia","correspondingAuthor":false,"prefix":"","firstName":"Valeria","middleName":"","lastName":"Mitro","suffix":""},{"id":514815823,"identity":"263ddae0-43f8-421e-8b14-1c9873f8e6e1","order_by":10,"name":"Antonio Tullio","email":"","orcid":"","institution":"Azienda Ospedaliera di Perugia","correspondingAuthor":false,"prefix":"","firstName":"Antonio","middleName":"","lastName":"Tullio","suffix":""}],"badges":[],"createdAt":"2025-08-28 16:08:27","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-7482022/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-7482022/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1007/s00238-026-02396-9","type":"published","date":"2026-01-31T15:58:11+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":91510830,"identity":"8836dd16-9a24-4feb-8923-5740d75e9a6c","added_by":"auto","created_at":"2025-09-17 08:45:29","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":273461,"visible":true,"origin":"","legend":"\u003cp\u003eCT angiography of the lower limbs DICOM data loaded and displayed on the open-source 3D slicer program.\u003c/p\u003e","description":"","filename":"1.png","url":"https://assets-eu.researchsquare.com/files/rs-7482022/v1/edceb54d14db373f38df2468.png"},{"id":91510835,"identity":"3852ed65-0f97-432d-94a6-910f7bde3dba","added_by":"auto","created_at":"2025-09-17 08:45:29","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":97016,"visible":true,"origin":"","legend":"\u003cp\u003eSegmented DICOM data, visualization of the fibula using 3D Slicer.\u003c/p\u003e","description":"","filename":"2.png","url":"https://assets-eu.researchsquare.com/files/rs-7482022/v1/0eae001d9a7877d78eaafe09.png"},{"id":91510833,"identity":"fce799df-deab-47b9-a09b-6d407d59d81f","added_by":"auto","created_at":"2025-09-17 08:45:29","extension":"png","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":57729,"visible":true,"origin":"","legend":"\u003cp\u003eView of the fibula without the 7 cm proximal and distal. Segment used for the reported morphometric measurements, using the program tools.\u003c/p\u003e","description":"","filename":"3.png","url":"https://assets-eu.researchsquare.com/files/rs-7482022/v1/0081c764b0c63cb0cfb08a88.png"},{"id":91510831,"identity":"5512ef5c-25c3-4a22-b319-519f991ead45","added_by":"auto","created_at":"2025-09-17 08:45:29","extension":"png","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":13512,"visible":true,"origin":"","legend":"\u003cp\u003eDistribution of fibulae width (x axis) and thickness (y axis) in males expressed in mm. The mean values of these parameters have been highlighted in red while the fibula with the shortest Euclidean distance from the mean has been highlighted in green.\u003c/p\u003e","description":"","filename":"4.png","url":"https://assets-eu.researchsquare.com/files/rs-7482022/v1/9118afa1ad0ad0d85eed2608.png"},{"id":91510837,"identity":"f1640809-46f3-46b1-9684-d666c54aaad7","added_by":"auto","created_at":"2025-09-17 08:45:29","extension":"png","order_by":5,"title":"Figure 5","display":"","copyAsset":false,"role":"figure","size":15129,"visible":true,"origin":"","legend":"\u003cp\u003eDistribution of fibulae width (x axis) and thickness (y axis) in females expressed in mm. The mean values of these parameters have been highlighted in red while the fibula with the shortest Euclidean distance from the mean has been highlighted in green.\u003c/p\u003e","description":"","filename":"5.png","url":"https://assets-eu.researchsquare.com/files/rs-7482022/v1/e9f214bbbe9dd6087ac57d8e.png"},{"id":101690420,"identity":"db89e44f-273c-4d66-95c2-8edd3186d0fb","added_by":"auto","created_at":"2026-02-02 16:01:51","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1325388,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-7482022/v1/d41b36b9-ae62-4ca3-83f6-04b3647e9444.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"\u003cp\u003eUse of stock DICOM data of fibular bone for CAD-CAM design in facial reconstruction by free fibula flap\u003c/p\u003e","fulltext":[{"header":"Introduction","content":"\u003cp\u003eSince its introduction in the 1970s [\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e], the free fibula flap (FFF) has played a central role in reconstruction of the facial skeleton. It is a highly versatile flap and remains the most widely used option for osseous reconstruction of the facial region due to the ample availability of bone and the adequate length of its vascular pedicle [\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e, \u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e]. However, in a non-negligible percentage of cases (5\u0026ndash;10%), the flap cannot be harvested safely due to concerns regarding sufficient vascularization of the foot [\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e]. For this reason, various techniques have been described in the literature to assess the course and patency of the peroneal and tibial vessels and therefore a safe harvest of the flap [\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e]. Currently, the most commonly used examination is lower limb CT angiography, which offers the advantage of providing highly detailed DICOM data, useful not only for vascular evaluation but also for morphological analysis of the fibula [\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e]. Since the 2000s, CAD-CAM technologies have been increasingly adopted in surgical practice, enabling the virtual planning and real-time 3D printing of anatomical models and cutting guides based on DICOM files. These innovations have improved surgical precision and reduced operative time [\u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e]. However, CT angiography also presents some drawbacks, including exposure to ionizing radiation and the need for contrast medium administration. The aim of this study is to propose a valid alternative to CT angiography for acquiring DICOM data of the fibula, while still enabling virtual planning and the production of 3D models and cutting guides for surgical procedures.\u003c/p\u003e"},{"header":"Material and methods","content":"\u003cp\u003eA total of 20 fibulae from male patients and 20 fibulae from female patients were included in this anatomical study. DICOM data were acquired through lower limb CT scans performed at the Azienda Ospedaliera of Perugia. Patients included in the study ranged from 18 to 70 years of age and underwent CT imaging for various clinical indications. Patients with current or previous fibular fractures, as well as those with osteo-deforming diseases, were excluded. Two separate databases were created based on sex, due to the evident differences in bone size and morphology. The distal and proximal 7 cm of each fibula were excluded from the analysis, as these segments are not usable in reconstructive surgery. Fibula segmentation and morphometric measurements were performed using the open-source software 3D-Slicer. Width and thickness were measured in the midpoint of the fibula.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eThe DICOM data of the selected CT angiography were uploaded to the 3D slicer program as shown in figure 1.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e(Figure 1)\u003c/p\u003e\n\u003cp\u003eThe data were segmented and cleaned to remove the other anatomical parts that are not of interest for this study as shown in figure 2.\u003c/p\u003e\n\u003cp\u003e(Figure 2)\u003c/p\u003e\n\u003cp\u003eFinally, after obtaining the segment of the fibula stripped of the 7 cm distal and proximal, measurements were taken.\u003c/p\u003e\n\u003cp\u003e(Figure 3)\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eStatistical analysis\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eMorphometric parameters of male and female fibulae (length, width, thickness and volume) were firstly assessed with the Kolmogorov-Smirnov test, which confirmed normal data distribution in both groups. Subsequently, intergroup differences between male and female fibulae measurements were analyzed using the Student’s t-test for independent samples. Among the measured parameters, width and thickness were identified as the most representative variables for the design of a stock fibular anatomical model and corresponding cutting guide. For these two parameters the coefficient of variation (CV) was calculated to quantify the intra-group variability. Representative specimens for male and female cohorts were selected using a closest-to-mean approach, based on the Euclidean distance between individual fibulae morphometric parameters (width and thickness) and their corresponding group means values. The specimen with the shortest Euclidean distance was the one designated as a stock model. To assess the accuracy and the potential clinical applicability of the selected stock models, the mean absolute error (MAE) was computed from the differences in both parameters between the representative specimen and the remaining fibulae, and the clinical coverage (CC) was calculated as the percentage of fibulae within a maximum tolerance of ± 2mm for both parameters.\u003c/p\u003e"},{"header":"Results","content":"\u003cp\u003e(Table 1)\u003c/p\u003e\n\u003cp\u003eFor the male group the mean length of the fibula was 24.67 ± 0.70 cm (SD 1,59 cm) with a maximum of 27.06 cm and a minimum of 22.49 cm. The mean width was 12.47 ± 0.47 mm (SD 1.08 mm) with a maximum of 14.72 mm and a minimum of 10.24 mm. The mean thickness was 10.64 ± 0.49 mm (SD 1,11 mm) with a maximum of 12.50 mm and a minimum of 8.32 mm. The mean volume was 3.29 ± 0.25 cm\u003csup\u003e3\u0026nbsp;\u003c/sup\u003e(SD 0.58 cm\u003csup\u003e3\u003c/sup\u003e) with a maximum of 4.19 cm\u003csup\u003e3\u0026nbsp;\u003c/sup\u003eand a minimum of 2.21 cm\u003csup\u003e3\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003e(Table 2)\u003c/p\u003e\n\u003cp\u003eFor the female group the mean length of the fibula was 22.26 ± 0.65 cm (SD 1.49 cm) with a maximum of 24.97 cm and a minimum of 19.97 cm. The mean width was 10.85 ± 0.52 mm (SD 1.18 mm) with a maximum of 12.83 mm and a minimum of 8.73 mm. The mean thickness was 8.59 ± 0.54 mm (SD 1,24 mm) with a maximum of 10.17 mm and a minimum of 6.31 mm. The mean volume was 2.12 ± 0.27 cm\u003csup\u003e3\u0026nbsp;\u003c/sup\u003e(SD 0.62 cm\u003csup\u003e3\u003c/sup\u003e) with a maximum of 3.19 cm\u003csup\u003e3\u0026nbsp;\u003c/sup\u003eand a minimum of 1.11 cm\u003csup\u003e3\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003eStatistically significant differences between males and females were observed for all measured parameters:\u003c/p\u003e\n\u003cul\u003e\n \u003cli\u003eLength male vs femaleà\u0026nbsp;p-value\u0026lt;0,00001\u003c/li\u003e\n \u003cli\u003eWidth male vs femaleà\u0026nbsp;p-value=0,000027\u003c/li\u003e\n \u003cli\u003eThickness male vs femaleà\u0026nbsp;p-value\u0026lt;0,00001\u003c/li\u003e\n \u003cli\u003eVolume male vs femaleà\u0026nbsp;p-value\u0026lt;0,00001\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003eThese findings confirm the need of developing two distinct stock models for male and female fibulae.\u003c/p\u003e\n\u003cp\u003eWidth and thickness were selected as the most suitable for the design of a fibula stock model. For these two parameters the variability was considered sufficiently low to assess their reliability in both groups:\u003c/p\u003e\n\u003cul\u003e\n \u003cli\u003eCV of width in malesà\u0026nbsp;8,66%\u0026nbsp;\u003c/li\u003e\n \u003cli\u003eCV of thickness in malesà\u0026nbsp;10,43%\u003c/li\u003e\n \u003cli\u003eCV of width in femalesà\u0026nbsp;10,88%\u003c/li\u003e\n \u003cli\u003eCV of thickness in femalesà\u0026nbsp;14,43%\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003e(Figure 4, Table 3)\u003c/p\u003e\n\u003cp\u003eThe selected specimen for males had a width of 12.20 mm and a thickness of 10.60 mm with a Euclidean distance from the mean of 0.27 mm. The mean Euclidean distance in males was 1.28 mm.\u003c/p\u003e\n\u003cp\u003e(Figure 5, Table 3)\u003c/p\u003e\n\u003cp\u003eThe selected specimen for females had a width of 10.99 mm and a thickness of 8.48 mm with a Euclidean distance from the mean of 0.18 mm. The mean Euclidean distance in females was 1.38 mm.\u003c/p\u003e\n\u003cp\u003e(Table 4)\u003c/p\u003e\n\u003cp\u003eThe Mean Absolut Error (MAE) between the selected stock model and remaining fibulae was consistently below ± 2mm of tolerance reported in scientific literature in both groups for width and thickness:\u003c/p\u003e\n\u003cul\u003e\n \u003cli\u003eMAE of width in malesà\u0026nbsp;± 0.89 mm\u003c/li\u003e\n \u003cli\u003eMAE of thickness malesà\u0026nbsp;± 0.96 mm\u003c/li\u003e\n \u003cli\u003eMAE of width femalesà\u0026nbsp;± 0.98 mm\u0026nbsp;\u003c/li\u003e\n \u003cli\u003eMAE of thickness femalesà\u0026nbsp;± 1.07 mm\u0026nbsp;\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003eThe overall Clinical Coverage (CC) was of 89.47%; in two cases (5.26%) both parameters exceeded the ± 2 mm tolerance, while in another two cases (5.26%) only one parameter was outside the tolerance range.\u003c/p\u003e"},{"header":"Discussion","content":"\u003cp\u003eSince the early use of the fibula in reconstructions, the necessity for a reliable examination to assess the presence and patency of the peroneal and tibial vessels in the leg has been recognized. Several alternatives have been proposed in the literature, among which CT angiography of the lower limbs has emerged as the gold standard [\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e]. This examination allows for an effective evaluation of the tibial and peroneal vessels and also provides DICOM data of the fibula, enabling preoperative assessments and planning directly on the bone that will subsequently be harvested for reconstruction. CT angiography proves particularly useful in preventing vascular complications in the foot; however, it remains a procedure that requires the infusion of iodinated contrast medium [\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e]. As is well established, iodinated contrast is nephrotoxic and cannot be administered to patients with renal insufficiency (GFR\u0026thinsp;\u0026lt;\u0026thinsp;45 ml/min), unless the risks of further impairing renal function are deemed acceptable [\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e]. Furthermore, there is the issue of allergic reactions, with some patients experiencing severe reactions that necessitate the suspension of the examination and significant delays in the diagnostic and therapeutic process [\u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e]. Given that many patients undergoing such interventions are affected by malignant neoplasms, the time factor is of paramount importance. Additionally, like any CT examination, CT angiography involves the use of ionizing radiation. In light of these considerations, color Doppler ultrasound has been increasingly utilized as a preoperative examination to evaluate the vascularization of the leg [\u003cspan additionalcitationids=\"CR10\" citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR11\" class=\"CitationRef\"\u003e11\u003c/span\u003e]. While this method is employed in the literature, it has never surpassed CT angiography, primarily due to the inability to study and acquire bone data for the customized planning of reconstructions. The inability to obtain DICOM data of the fibula represents the principal limitation to the validation of this intervention using color Doppler ultrasound. To address this issue, a fibula database (one for males and one for females) has been created in order to ascertain whether the differences between various fibulae are sufficiently large to preclude segmentation and customized planning, even when using a stock peroneal bone. The analysis excluded the distal and proximal 7 cm segments of the fibula, as these regions are necessary for ensuring the stability of the knee and ankle joints and are therefore not utilized in the reconstruction [\u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e]. The fibula selected as a model for both males and females was chosen based on width and thickness, selecting the fibula that deviated least from these values. The statistical difference between males and females suggest the need for two different databases. Length was not considered a parameter for selecting the stock fibula, as it does not influence the dimensions of the peroneal segments actually used in reconstruction. Instead, the minimum measured lengths (22 cm for males and 20 cm for females) were considered as the hypothetical maximum usable bone length for planning purposes. The bone volume of the fibula is a parameter that can be useful in reconstruction planning. By comparing the volume of the resected mandibular/maxillary bone with the estimated volume of the fibula, one can confirm the reconstruction plan or consider shifting to other reconstructive grafts, such as the iliac crest, should the expected volumetric differences prove too significant. The principal critique of this technique is that it creates a customized plan, which hinges on precision as its key advantage, using a fibula that is not the patient's own, thus introducing a degree of approximation. The objective of this study is to estimate the extent of this approximation and determine whether it remains within acceptable limits. Literature evidence suggests that this degree of approximation is indeed acceptable, as similar reconstructions of the facial skeleton, considered successful, also carry a margin of error when compared to the digital plan, typically within 2 mm [\u003cspan additionalcitationids=\"CR13\" citationid=\"CR12\" class=\"CitationRef\"\u003e12\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e]. In the operating room, there is inevitably some discrepancy between the surgical plan and the actual procedure, just as the use of a stock fibula requires a degree of tolerance compared to the patient's own fibula. Considering the statistical results obtained; a MAE of approximately 1 mm, which is below the tolerance threshold of 2mm, and a clinical coverage of 89.47%; it can be concluded that the variability of the fibula is low enough and therefore does not compromise the reconstructive outcome. The critical challenges of this method are primarily related to reconstructive plans for large defects and the use of customized plates, where the mandibular contouring with titanium must accommodate the fibula within the plate itself. In the clinical practice of this center, the philosophy is to minimize the titanium content in the plate to the minimum required to support the load-bearing forces of the reconstructed segment [\u003cspan citationid=\"CR15\" class=\"CitationRef\"\u003e15\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR16\" class=\"CitationRef\"\u003e16\u003c/span\u003e]. This reconstructive philosophy aligns well with the proposed technique. It is acknowledged that for more extreme cases, where the volume of bone required for reconstruction is close to the limits of these parameters, it may be safer to perform at least a CT scan of the lower limb to utilize the patient's own DICOM data. This would allow the avoidance of iodinated contrast and reduce the amount of radiation administered to the patient.\u003c/p\u003e"},{"header":"Conclusion","content":"\u003cp\u003eThe choice of an examination to assess the vascularization of the foot in the case of a fibula free flap reconstruction is crucial. Color Doppler ultrasound allows for a reliable assessment of the foot's vascularization avoiding IR and contrast medium. However, this does not preclude the possibility of performing a customized reconstruction using stock fibula data that represent the general population. The differences between the various fibulae are minimal and, in our opinion, can be considered acceptable.\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003eThe authors declare that no funds, grants, or other support were received during the preparation of this manuscript.\u003c/p\u003e\n\u003cp\u003eThe authors have no relevant financial or non-financial interests to disclose.\u003c/p\u003e\n\u003cp\u003eAll authors contributed to the study conception and design. All authors read and approved the final manuscript.\u003c/p\u003e\n\u003cp\u003eThis study was performed in line with the principles of the Declaration of Helsinki.\u003c/p\u003e\n\u003cp\u003eHuman Ethics and Consent to participate declarations: not applicable.\u003c/p\u003e\n\u003cp\u003eThe S. Maria della Misericordia Hospital Research Ethics Committee (CER Umbria) \u0026nbsp;has confirmed that no ethical approval is required.\u003c/p\u003e\n\u003cp\u003eInformed consent was obtained from all individual participants included in the study.\u003c/p\u003e\n\u003cp\u003eClinical trial number: not applicable\u003c/p\u003e\u003ch2\u003eAuthor Contribution\u003c/h2\u003e\u003cp\u003eMassimiliano Gilli study ideaAntonio Bimonte statisticUmberto Committeri data segmentationGabriele Monarchi english revisorAngela Rosa Caso reference Federica Sacchi data collectionMaria Elisa Giovannoni data collectionGiuseppe Consorti surgeonFrancesco Giovacchini surgeonValeria Mitro table creatorAntonio Tullio supervision\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n\u003cli\u003eTaylor, G. I., Miller, G. D., \u0026amp; Ham, F. J. (1975). The free vascularized bone graft. A clinical extension of microvascular techniques. Plast Reconstr Surg 55(5), 533\u0026ndash;544.\u003c/li\u003e\n\u003cli\u003eGilli, M., Committeri, U., Monarchi, G. et al. Mean Arterial Pressure (MAP) influence on free flap oxygen saturation (StO2) measured by near-infrared spectroscopy (2025). Eur J Plast Surg 48, 29 https://doi.org/10.1007/s00238-025-02288-4\u003c/li\u003e\n\u003cli\u003eGiovacchini F, Monarchi G, Mitro V et al (2021) Maxilla reconstruction using a free fibula flap and virtual planning. Chirurgia 34(5):227\u0026ndash;231.\u003c/li\u003e\n\u003cli\u003eGryseleyn, R., Schlund, M., Pigache, P., Wojcik, T., Raoul, G., \u0026amp; Ferri, J. (2017). Influence of preoperative imaging on fibula free flap harvesting. J Stomatol Oral Maxillofac Surg, 118(5), 265\u0026ndash;270. https://doi.org/10.1016/j.jormas.2017.05.002\u003c/li\u003e\n\u003cli\u003eGiovacchini F, Gilli M, Mitro V et al (2021) Rapid prototyping: applications in oral and maxillofacial surgery. J Oral Med Oral Surg 27:11\u003c/li\u003e\n\u003cli\u003eKaranas, Y. L., Antony, A., Rubin, G., \u0026amp; Chang, J. (2004). Preoperative CT angiography for free fibula transfer. Microsurgery, 24(2), 125\u0026ndash;127. https://doi.org/10.1002/micr.20009\u003c/li\u003e\n\u003cli\u003eNyman, U., Ahlkvist, J., Aspelin, P., Brismar, T., Frid, A., Hellstr\u0026ouml;m, M., Liss, P., Sterner, G., Leander, P., \u0026amp; Contrast Media Committee of the Swedish Society of Uroradiology and in collaboration with the Swedish Society of Nephrology (GS) and the Swedish Society of Diabetology (AF) (2018). Preventing contrast medium-induced acute kidney injury: Side-by-side comparison of Swedish-ESUR guidelines. Eur Radiol, 28(12), 5384\u0026ndash;5395. https://doi.org/10.1007/s00330-018-5678-6.\u003c/li\u003e\n\u003cli\u003eByrne, A., Macdonald, D. B., Kirkpatrick, I. D. C., Pham, M., Green, C. R., Copaescu, A. M., McInnes, M. D. F., Ling, L., Ellis, A., \u0026amp; Costa, A. F. (2025). CAR/CSACI Practice Guidance for Contrast Media Hypersensitivity. Can Assoc Radiol J, 76(3), 400\u0026ndash;416. https://doi.org/10.1177/08465371241311253.\u003c/li\u003e\n\u003cli\u003eFutran, N. D., Stack, B. C., Jr, \u0026amp; Zaccardi, M. J. (1998). Preoperative color flow Doppler imaging for fibula free tissue transfers. Ann Vasc Surg, 12(5), 445\u0026ndash;450. https://doi.org/10.1007/s100169900182.\u003c/li\u003e\n\u003cli\u003eSmith, R. B., Thomas, R. D., \u0026amp; Funk, G. F. (2003). Fibula free flaps: the role of angiography in patients with abnormal results on preoperative color flow Doppler studies. Arch Otolaryngol Head Neck Surg, 129(7), 712\u0026ndash;715. https://doi.org/10.1001/archotol.129.7.712.\u003c/li\u003e\n\u003cli\u003eWhitley, S. P., Sandhu, S., \u0026amp; Cardozo, A. (2004). Preoperative vascular assessment of the lower limb for harvest of a fibular flap: the views of vascular surgeons in the United Kingdom. Br J Oral Maxillofac Surg, 42(4), 307\u0026ndash;310. https://doi.org/10.1016/j.bjoms.2004.02.019.\u003c/li\u003e\n\u003cli\u003eDell\u0026apos;Aversana Orabona, G., Abbate, V., Maglitto, F., Bonavolont\u0026agrave;, P., Salzano, G., Romano, A., Reccia, A., Committeri, U., Iaconetta, G., \u0026amp; Califano, L. (2018). Low-cost, self-made CAD/CAM-guiding system for mandibular reconstruction. Surg Oncol, 27(2), 200\u0026ndash;207. https://doi.org/10.1016/j.suronc.2018.03.007.\u003c/li\u003e\n\u003cli\u003eTarsitano, A., Battaglia, S., Ricotta, F., Bortolani, B., Cercenelli, L., Marcelli, E., Cipriani, R., \u0026amp; Marchetti, C. (2018). Accuracy of CAD/CAM mandibular reconstruction: A three-dimensional, fully virtual outcome evaluation method. J Craniomaxillofac Surg, 46(7), 1121\u0026ndash;1125. https://doi.org/10.1016/j.jcms.2018.05.010.\u003c/li\u003e\n\u003cli\u003eSweed, A. H., Bolzoni, A. R., Kadubiec, A., Beltramini, G. A., Cherchi, A., \u0026amp; Baj, A. (2020). Factors influencing CAD/CAM accuracy in fibula free flap mandibular reconstruction. Acta Otorhinolaryngol Ital, 40(2), 138\u0026ndash;143. https://doi.org/10.14639/0392-100X-N0400.\u003c/li\u003e\n\u003cli\u003eGilli, M., Giovacchini, F., Mitro, V., Sacchi, F., Committeri, U., Caso, A.R., Monarchi, G., \u0026amp; Tullio, A. (2025). Near-Infrared Spectroscopy Sensors, Which Type to Choose and How to Fix it in Cranio- and Maxillo-facial Reconstructive Surgery: Tip and Tricks. J Maxillofac Oral Surg.\u003c/li\u003e\n\u003cli\u003eNobis, C. P., Lutz, R., Weber, M., Preidl, R., Goetze, E., Frohwitter, G., \u0026amp; Kesting, M. R. (2022). Performance of different osteosynthesis materials in microvascular fibula free flap reconstruction. Br J Oral Maxillofac Surg, 60(5), 623\u0026ndash;628. https://doi.org/10.1016/j.bjoms.2021.10.013\u003c/li\u003e\n\u003c/ol\u003e"},{"header":"Tables","content":"\u003cp\u003eTab.1 shows the data of the 20 fibulae examined for the male population. The distal and proximal 7 cm segments, which are unusable for reconstruction, have already been excluded from the data reported. Each fibula is described by its length, width, thickness, and volume. The respective means, standard deviations and confidence intervals (95%) are reported.\u003c/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\" width=\"633\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"5\" valign=\"top\" style=\"width: 633px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eMale patients\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eLenght (cm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eWidth (mm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eThickness (mm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eVolume (cm\u003csup\u003e3\u003c/sup\u003e)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e26.01\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e12.69\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e10.46\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e3.45\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e25.38\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e11.55\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e9.55\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e2.81\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e26.66\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e12.01\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e11.02\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e3.52\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e24.08\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e13.00\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e11.48\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e3.59\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e25.93\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e12.89\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e10.85\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e3.62\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e25.95\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e11.68\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e9.28\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e2.81\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e24.58\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e10.78\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e8.32\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e2.24\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e26.00\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e12.53\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e10.37\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e3.37\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e24.25\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e11.67\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e9.29\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e2.62\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e22.50\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e12.23\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e11.60\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e3.19\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e22.99\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e13.68\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e11.39\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e3.58\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e27.06\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e12.70\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e11.46\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e3.93\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e26.09\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e11.66\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e9.46\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e2.87\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e26.74\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e12.74\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e11.52\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e3.92\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e22.59\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e10.24\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e9.59\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e2.21\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e23.97\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e13.99\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e12.50\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e4.19\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e22.49\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e12.20\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e10.60\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e2.98\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e22.59\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e14.72\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e11.39\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e3.78\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e24.52\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e13,77\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e12.29\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e4.14\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e22.98\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e12.68\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e10.40\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e3.03\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e24.67\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e12.47\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e10.64\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e3.29\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eMean\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1.59\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1.08\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1.11\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.58\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSd\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 123px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.70\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.47\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 151px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.49\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 169px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.25\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eC.I.\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003eTab. 2 shows the data of the 20 fibulae examined for the female population. The distal and proximal 7 cm segments, which are unusable for reconstruction, have already been excluded from the data reported. Each fibula is described by its length, width, thickness, and volume. The respective means, standard deviations and confidence intervals (95%) characterizing the population under study are also reported.\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"630\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"5\" valign=\"top\" style=\"width: 630px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eFemale patients\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eLength (cm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eWidth (mm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eThickness (mm)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eVolume (cm\u003csup\u003e3\u003c/sup\u003e)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e23.73\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e11.79\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e9.14\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e2.56\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e21.38\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e10.74\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e8.06\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e1.85\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e24.52\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e12.83\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e10.17\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e3.19\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e21.33\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e10.38\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e8.88\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e1.96\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e22.88\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e11.77\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e9.08\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e2.44\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e22.71\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e11.03\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e9.94\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e2.48\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e21.32\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e10.38\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e8.13\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e1.79\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e22.82\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e11.85\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e9.94\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e2.68\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e20.35\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e9.67\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e7.02\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e1.38\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e22.24\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e10.98\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e8.38\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e2.04\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e24.97\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e11.94\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e9.16\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e2.73\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e21.66\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e10.66\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e8.42\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e1.94\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e23.20\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e12.03\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e10.16\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e2.83\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e19.97\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e8.94\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e6.31\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e1.12\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e20.86\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e9.42\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e7.22\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e1.41\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e22.33\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e11.25\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e9.46\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e2.37\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e21.11\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e9.22\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e7.35\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e1.43\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e24.08\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e10.99\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e8.48\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e2.24\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e23.68\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e12.31\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e10.11\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e2.91\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e19.97\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e8.73\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e6.39\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e1.11\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e22.26\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e10.85\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e8.59\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2.12\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eMean\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1.49\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1.18\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1.24\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.62\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSd\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.65\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.52\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.54\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 144px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.27\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 54px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eC.I.\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003eTab. 3 shows width and thickness of male and female fibulae and their Euclideand distance from the respective groups mean values. For each group, the fibula with the shortest Euclidean distance from the mean has been highlighted in green.\u003c/p\u003e\n\u003ctable style=\"border-collapse: collapse;border: none;width: 642px;\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"3\" style=\"width: 240.7pt;border-width: 1pt 1pt 1.5pt;border-style: solid;border-color: windowtext windowtext rgb(102, 102, 102);border-image: initial;background: rgb(191, 191, 191);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:21px;font-family:\"Times New Roman\";color:black;'\u003eMale\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 240.7pt;border-top: 1pt solid windowtext;border-left: none;border-bottom: 1.5pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;background: rgb(191, 191, 191);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:21px;font-family:\"Times New Roman\";color:black;'\u003eFemale\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003eWidth (mm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003eThickness (mm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003eEuclidean distance (mm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003eWidth (mm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003eThickness (mm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003eEuclidean distance (mm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e12.69\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e10.46\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\";'\u003e0.28\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e11.79\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e9.14\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;\"\u003e1.09\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e11.55\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e9.55\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003e1.43\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e10.74\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e8.06\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;color:black;\"\u003e0.54\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 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none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\";'\u003e0.60\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e12.83\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e10.17\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;\"\u003e2.53\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e11,48\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003e0.99\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e10.38\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e8.88\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;color:black;\"\u003e0.55\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\";'\u003e0.47\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e11.77\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e9.08\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;\"\u003e1.04\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e11.68\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e9.28\u003c/span\u003e\u003c/p\u003e\n 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style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e11.03\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e9.94\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;color:black;\"\u003e1.36\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e10.78\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 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none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;\"\u003e0.66\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New 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rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e9.94\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;color:black;\"\u003e1.68\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e11.67\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New 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style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e9.67\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e7.02\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;\"\u003e1.96\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e12.23\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e11.60\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003e0.99\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e10.98\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e8.38\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;color:black;\"\u003e0.25\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e13.68\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e11.39\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 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windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e12.70\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e10.66\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e8.42\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;color:black;\"\u003e0.25\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e11.66\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e9.46\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\";'\u003e1.43\u003c/span\u003e\u003c/p\u003e\n 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e12.74\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e11.52\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003e0.92\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e8.94\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e6.31\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;color:black;\"\u003e2.97\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e10.24\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e9.59\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\";'\u003e2.46\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e9.42\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e7.22\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;\"\u003e1.98\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 3pt solid rgb(0, 176, 80);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e13.99\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 3pt solid rgb(0, 176, 80);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e12.50\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 3pt solid rgb(0, 176, 80);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e9.46\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;color:black;\"\u003e0.96\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 3pt solid rgb(0, 176, 80);border-bottom: 3pt solid rgb(0, 176, 80);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e12.20\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 3pt solid rgb(0, 176, 80);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e10.60\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 3pt solid rgb(0, 176, 80);border-right: 3pt solid rgb(0, 176, 80);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\";'\u003e0.27\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 3pt solid rgb(0, 176, 80);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e9.22\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 3pt solid rgb(0, 176, 80);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e7.35\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 3pt solid rgb(0, 176, 80);border-right: 1pt solid windowtext;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;\"\u003e2.05\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e11.39\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 3pt solid rgb(0, 176, 80);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003e2.37\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 3pt solid rgb(0, 176, 80);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e10.99\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 3pt solid rgb(0, 176, 80);border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e8.48\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 3pt solid rgb(0, 176, 80);border-right: 3pt solid rgb(0, 176, 80);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;color:black;\"\u003e0.18\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e13.77\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e12.29\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\";'\u003e2.10\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e12.31\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid rgb(102, 102, 102);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;color:black;'\u003e10.11\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(102, 102, 102);border-right: 1pt solid windowtext;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;\"\u003e2.11\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e12.68\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e10.40\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\";color:black;'\u003e0.32\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e8.73\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid rgb(102, 102, 102);background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e6.39\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80.25pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style=\"font-size:16px;color:black;\"\u003e3.06\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003eTab.4 shows the differences for width and thickness in both groups between individual fibulae and the one selected as a stock model (highlighted in green). Fibulae that exceeded the 2mm tolerance in at least one of the two parameters have been highlighted in red.\u003c/p\u003e\n\u003ctable style=\"border-collapse: collapse;border: none;width: 642px;\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"2\" style=\"width: 240.55pt;border: 1pt solid black;background: rgb(191, 191, 191);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:21px;font-family:\"Times New Roman\",serif;color:black;'\u003eMale\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 240.55pt;border-top: 1pt solid black;border-right: 1pt solid black;border-bottom: 1pt solid black;border-image: initial;border-left: none;background: rgb(191, 191, 191);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:21px;font-family:\"Times New Roman\",serif;color:black;'\u003eFemale\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.25pt;border-right: 1pt solid black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;background: rgb(191, 191, 191);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003eDiff. Stock width \u0026nbsp;(mm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(191, 191, 191);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003eDiff. Stock thickness (mm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.25pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(191, 191, 191);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003eDiff. Stock width\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e(mm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(191, 191, 191);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003eDiff. Stock thickness (mm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.25pt;border-right: 1pt solid black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;'\u003e-0.49\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e0.14\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.25pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-0.80\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-0.66\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.25pt;border-right: 1pt solid black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e0.65\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e1.05\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.25pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e0.25\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e0.42\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.25pt;border-right: 1pt solid black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;'\u003e0.19\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-0.42\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.25pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-1.84\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-1.69\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.25pt;border-right: 1pt solid black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp 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none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e0.23\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.25pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e-0.86\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n 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style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e1.32\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e1.46\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.25pt;border-right: 1pt solid black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp 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black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;'\u003e-1.48\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-0.79\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.25pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-0.95\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-0.68\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.25pt;border-right: 1pt solid black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e-0.50\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e0.06\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.25pt;border-right: 1pt solid black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;'\u003e0.54\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e1.14\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.25pt;border-top: none;border-left: none;border-bottom: 3pt solid red;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-1.04\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 3pt solid red;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-1.68\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.25pt;border-right: 1pt solid black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e-0.54\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 3pt solid red;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e-0.92\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.25pt;border-top: none;border-left: none;border-bottom: 3pt solid red;border-right: 1pt solid black;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e2.05\u003c/span\u003e\u003c/p\u003e\n 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e-1.79\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 3pt solid red;border-right: 3pt solid red;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e-1.90\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.25pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e-0.26\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(204, 204, 204);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e-0.98\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.25pt;border-right: 1pt solid black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;background: rgb(0, 176, 80);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e0\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(0, 176, 80);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e-0.79\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.25pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(0, 176, 80);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e0\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;background: rgb(0, 176, 80);padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;color:black;'\u003e0\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 120.25pt;border-right: 1pt solid black;border-bottom: 1pt solid black;border-left: 1pt solid black;border-image: initial;border-top: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family:\"Times New Roman\",serif;'\u003e-1.57\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 1pt solid black;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-1.69\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.25pt;border-top: none;border-left: none;border-bottom: 3pt solid red;border-right: 1pt solid black;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:15px;font-family:\"Calibri\",sans-serif;text-align:center;'\u003e\u003cspan style='font-size:16px;font-family: \"Times New Roman\",serif;'\u003e-1.32\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 120.3pt;border-top: none;border-left: none;border-bottom: 3pt 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[email protected]","identity":"european-journal-of-plastic-surgery","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"ejps","sideBox":"Learn more about [European Journal of Plastic Surgery](https://link.springer.com/journal/238)","snPcode":"238","submissionUrl":"https://submission.nature.com/new-submission/238/3","title":"European Journal of Plastic Surgery","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"em","reportingPortfolio":"Springer Hybrid","inReviewEnabled":true,"inReviewRevisionsEnabled":false},"keywords":"Free fibula flap, Reconstructive surgery, facial reconstruction, fibula harvesting","lastPublishedDoi":"10.21203/rs.3.rs-7482022/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-7482022/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground\u003c/strong\u003e: The free fibula flap (FFF) is a cornerstone in facial skeletal reconstruction, but its harvest may be challenging in 5–10% of cases due to concerns over vascularization. While lower limb CT angiography is widely used to assess vascular patency, it involves ionizing radiation and iodinated contrast, posing risks, especially for patients with renal insufficiency or allergies. This study investigates the use of stock fibula models, derived from average anatomical measurements, as a reliable alternative to patient-specific fibulae for surgical planning, thereby eliminating the need for CT angiography. The safeness off fibula harvesting is guaranteed by US color Doppler.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods:\u003c/strong\u003e A total of 40 fibulas (20 male, 20 female) were analyzed using DICOM data obtained from standard CT scans. Data segmentation and measurement were performed by an open source softwere (3Dslicer).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults:\u003c/strong\u003e Statistical analysis showed significant differences in fibular dimensions between genders (p \u0026lt; 0.00001), with minimal variability (CV Width M: 8.66%, CV Thickness M: 10.43%, CV Width F: 10.88%, CV Thickness F: 14.43%), confirming the suitability of stock models for accurate reconstructive plans. Importantly, bypassing CT angiography eliminates radiation exposure and the administration of iodinated contrast, reducing patient risks.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion:\u003c/strong\u003e The results suggest that stock fibula models, based on population averages, provide an effective and safe solution for facial reconstruction, ensuring high surgical precision without the need for CT angiography or contrast agents.\u003c/p\u003e","manuscriptTitle":"Use of stock DICOM data of fibular bone for CAD-CAM design in facial reconstruction by free fibula flap","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-09-17 08:45:25","doi":"10.21203/rs.3.rs-7482022/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Revision requested","date":"2025-09-14T12:37:33+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-09-12T05:28:25+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"113302014107574385011316244282176501654","date":"2025-09-12T05:14:49+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2025-09-09T15:18:33+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2025-09-01T13:45:21+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2025-09-01T13:42:46+00:00","index":"","fulltext":""},{"type":"submitted","content":"European Journal of Plastic Surgery","date":"2025-08-28T16:00:34+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"
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