LHRH ANTAGONISTS AND INTERMEDIATE PRODUCTS

1995
OA: closed

Abstract

The invention concerns LHRH antagonists of the general formula (I), in which X is an acyl group, X1 is a D-Nal, X2 is D-(4-Cl)-Phe, X3 is D-(3)-Pal, X6 is D-Cit or D-Neu, X8 is L-Arg or L-Neu, at least one of the groups X6 and X8 being a Neu, and X10 is D-Ala-NH2, Neu being a group of formulae (II), (III) ou (IV), wherein W is one of the group (a), (b), (c) or (d). The invention includes drugs containing a compound of formula (I), plus the usual auxiliaries and carriers. These drugs are suitable for use in cases of carcinoma of the prostate and in endometriosis, as well as for fertility control.

My notes (saved in your browser only)

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc
last seen: 2026-07-06T06:10:23.601157+00:00