Comparative analysis of visual performance and astigmatism tolerance with monofocal, bifocal, and extended depth-of-focus intraocular lenses targeting slight myopia

Background: To compare the visual performance and astigmatism tolerance of 3 intraocular lens (IOLs): monofocal, bifocal, and extended depth-of-focus (EDOF) IOLs targeting slight myopia. Methods: Overall, there were 60 cataract surgery eyes from 60 patients with implantation of a monofocal, bifocal or EDOF IOL (20 eyes in each IOL group). The EDOF IOLs targeted slight myopia (-0.25 D to -0.75 D). Intragroup comparison of visual acuity, defocus curve, objective optical quality, contrast sensitivity, Visual function questionnaire scores, patients’ overall satisfaction, and the astigmatism tolerance were performed 3 months after surgery. Results: The EDOF group provided equivalently excellent distance visual outcomes (0.06±0.12) as the monofocal (0.06±0.09) and bifocal (0.03±0.09) groups (P=0.554), better intermediate vision than the other 2 groups (P0.05). The contrast sensitivity of EDOF IOL was slightly decreased compared to that of monofocal IOL, but it was better than that of bifocal IOL. The EDOF group showed significantly higher satisfaction than the bifocal group did when preoperative corneal astigmatism was 0.75 D or greater (P=0.009). A significant negative correlation between the corneal astigmatism and patient satisfaction was observed in only the bifocal group. Conclusions: The EDOF IOLs targeting slight myopia offered satisfactory visual outcomes at an extended range from far to near distances. The EDOF and monofocal IOLs showed a better tolerance to astigmatism than did the bifocal IOL.