Postoperative opioid use for patients with chronic pelvic pain undergoing robotic surgery for resection of endometriosis

article OA: closed CC0 ⤵ 4 in-corpus citations
AI-generated summary by claude@2026-06+body, 2026-06-12

Robotic surgery for endometriosis in patients with chronic pelvic pain required over two times more postoperative opioids than for other benign gynecologic procedures.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

AI-generated deep summary by claude@2026-06, 2026-06-12 · read from full text

This retrospective cohort study evaluated postoperative opioid use after robotic surgery in 158 patients with chronic pelvic pain or other benign indications at an urban academic hospital (Jan 2019–Mar 2020), comparing 119 undergoing robotic excision of endometriosis with 39 undergoing other benign robotic gynecologic procedures. Postoperative opioid consumption was measured using patient-reported survey data at a 3-week follow-up and expressed as morphine milligram equivalents (MME). Patients with endometriosis used an average of 105.9 MME (about 14 oxycodone 5 mg tabs) versus 49.4 MME (about 6 oxycodone 5 mg tabs) in patients without endometriosis; opioid use did not differ significantly by endometriosis stage or whether hysterectomy was needed, and the authors report higher perceived postoperative pain in the endometriosis group. The study is limited by its retrospective design and reliance on patient-reported opioid use at a single time point, which may introduce recall and reporting bias. This paper is centrally about endometriosis — it quantifies postoperative opioid use and perceived postoperative pain after robotic resection of endometriosis in patients with chronic pelvic pain.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Full text 8,342 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Abstract

We aimed to identify the amount of opioids used in the postoperative setting for patients with a history of chronic pelvic pain undergoing robotic surgical excision of endometriosis and compare this to patients undergoing benign robotic gynecologic surgery for other indications. We conducted a retrospective cohort study in an urban academic university hospital from January 2019 to March 2020. Data regarding opioid use was collected via a patient-reported survey that was given at the 3 weeks follow-up visit. Data regarding opioid use was compared to patients undergoing robotic surgery for other benign gynecologic indications. Our study included 158 patients, 119 undergoing surgery for endometriosis and 39 patients undergoing robotic surgery for other benign gynecologic indications. Patients undergoing surgery for endometriosis used on average 105.9 morphine milligram equivalents (MME), equivalent to 14 tabs of oxycodone 5 mg. There was no statistically significant difference in the amount of opioids used postoperatively based on stage of endometriosis or need for hysterectomy. Patients undergoing surgery for other benign indications used on average 49.4 MME, equivalent to 6 tabs of oxycodone 5 mg. The difference in amount of opioids used between patients with and without endometriosis was statistically significant. In conclusion, patients undergoing robotic surgery for endometriosis used over two times as many opioids postoperatively as patients without endometriosis and have a higher perceived postoperative pain. Providers should be aware of this difference in order to provide better pain control for this patient population. Similar content being viewed by others Availability of data and material The data that support the findings of this study are available on request from the corresponding author, XG. The data are not publicly available due to their containing information that could compromise the privacy of research participants. Code availability The codes for this study are available on request from the corresponding author, XG. The data are not publicly available due to their containing information that could compromise the privacy of research participants.

References

Practice T, Medicine R (2014) Treatment of pelvic pain associated with endometriosis: a committee opinion. Fertil Steril 101(4):927–935. https://doi.org/10.1016/j.fertnstert.2014.02.012 ACOG (2019) PB Chronic Pelvic Pain. Obstet Gynecol 133(76):168–186 Mathias SD, Kuppermann M, Liberman R, Lipschutz R, Steege J (1996) Chronic pelvic pain: prevalence, health-related quality of life and economic correlates. Obstet Gynecol 87(3):321–327 ACOG (2010) Management of endometriosis. Practice bulletin no.114. American college of obstetricians and gynecologists. Obstet Gynecol 2010(116):223–236 Surgery R, Conditions NG (2004) ACOG committee opinion #297. Obstet Gynecol 104(2):423–424. https://doi.org/10.1097/00006250-200408000-00049 Huang Y, Duan K, Koythong T et al (2021) Application of robotic single-site surgery with optional additional port for endometriosis: a single institution’s experience. J Robot Surg. https://doi.org/10.1007/s11701-021-01217-4 Guan X, Nguyen MTA, Walsh TM, Kelly B (2016) Robotic single-site endometriosis resection using firefly technology. J Minim Invasive Gynecol 23(1):10–11. https://doi.org/10.1016/j.jmig.2015.08.001 Centers for Disease Control and Prevention (United States) (2021) Drug overdose deaths [internet]. Available at: https://www.cdc.gov/drugoverdose/data/statedeaths.html. Accessed 2 Feb 2021 Volkow ND, Jones EB, Einstein EB, Wargo EM (2019) Prevention and treatment of opioid misuse and addiction: a review. JAMA Psychiat 76(2):208–216. https://doi.org/10.1001/jamapsychiatry.2018.3126 Makary MA, Overton HN, Wang P (2017) Overprescribing is major contributor to opioid crisis. BMJ 359:19–20. https://doi.org/10.1136/bmj.j4792 Hill MV, Mcmahon ML, Stucke RS, Barth RJ (2017) Wide variation and excessive dosage of opioid prescriptions for common general surgical procedures. Ann Surg 265(4):709–714. https://doi.org/10.1097/SLA.0000000000001993 Madsen AM, Stark LM, Has P, Emerson JB, Schulkin J, Matteson KA (2018) Opioid knowledge and prescribing practices among obstetrician-gynecologists. Obstet Gynecol 131(1):150–157. https://doi.org/10.1097/AOG.0000000000002407 Bengtson J (2009) Womens Health care center for Womens health. Am J Crit Care. https://doi.org/10.4037/ajcc2011673 Wong M, Vogell A, Wright K, Isaacson K, Loring M, Morris S (2019) Opioid use after laparoscopic hysterectomy: prescriptions, patient use, and a predictive calculator. Am J Obstet Gynecol 220(3):259.e1-259.e11. https://doi.org/10.1016/j.ajog.2018.10.022 Patanwala I, Ouyang C, Fisk M, Lamvu G (2020) Opioid prescription usage after benign gynecologic surgery: a prospective cohort study. J Minim Invasive Gynecol 27(4):860–867. https://doi.org/10.1016/j.jmig.2019.07.007 Lovich-Sapola J, Smith CE, Brandt CP (2015) Postoperative pain control. Surg Clin N Am 95(2):301–318. https://doi.org/10.1016/j.suc.2014.10.002 Centers for Disease Control and Prevention (United States) (2017) Calculating total daily dose of opioids for safer dosage [internet]. Available at: http://www.cdc.gov/drugoverdose/pdf/calculating_total_daily_dose-a.pdf. Accessed 14 Jan 2021 Griffith KC, Clark NV, Zuckerman AL, Ferzandi TR, Wright KN (2018) Opioid prescription and patient use after gynecologic procedures: a survey of patients and providers. J Minim Invasive Gynecol 25(4):684–688. https://doi.org/10.1016/j.jmig.2017.11.005 As-Sanie S, Till SR, Mowers EL et al (2017) Opioid prescribing patterns, patient use, and postoperative pain after hysterectomy for benign indications. Obstet Gynecol 130(6):1261–1268. https://doi.org/10.1097/AOG.0000000000002344 Carvalho B, Zheng M, Harter S, Sultan P (2016) A prospective cohort study evaluating the ability of anticipated pain, perceived analgesic needs, and psychological traits to predict pain and analgesic usage following cesarean delivery. Anesthesiol Res Pract. https://doi.org/10.1155/2016/7948412 Vercellini P, Trespidi L, De Giorgi O, Cortesi I, Parazzini F, Crosignani PG (1996) Endometriosis and pelvic pain: relation to disease stage and localization. Fertil Steril 65(2):299–304. https://doi.org/10.1016/s0015-0282(16)58089-3 Parazzini F, Cipriani S, Moroni S et al (2001) Relationship between stage, site and morphological characteristics of pelvic endometriosis and pain. Hum Reprod 16(12):2668–2671. https://doi.org/10.1093/humrep/16.12.2668 Funding No funding was received for conducting this study. Author information Authors and Affiliations Contributions All authors named on this submission made substantial contributions to the study. Material preparation, data collection and analysis were by SD, TK, MT, and XG. HS-H performed all statistical analysis. The first draft of the manuscript was written by SD and all authors commented on previous versions of the manuscript and approved the final manuscript. Corresponding author Ethics declarations Conflict of interest Dr. S Delgado, MD, T Koythong, MD, M Turrentine, MD, H Sangi-Haghpeykar, X Guan, MD declare that they have no financial disclosures or conflicts of interests. Ethics approval This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the IRB for Baylor College of Medicine. Approval Date: 3/30/2020. IRB Number: H-47180. Informed consent All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000. Informed consent was obtained from all patients for being included in the study. Additional information Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Rights and permissions About this article Cite this article Delgado, S.I., Koythong, T., Turrentine, M.A. et al. Postoperative opioid use for patients with chronic pelvic pain undergoing robotic surgery for resection of endometriosis. J Robotic Surg 16, 421–427 (2022). https://doi.org/10.1007/s11701-021-01259-8 Received: Accepted: Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s11701-021-01259-8

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Endometriosis Endometriosis Robotic Surgical Procedures Robotic Surgical Procedures Analgesics, Opioid Analgesics, Opioid Female Humans Pelvic Pain Pelvic Pain Pelvic Pain Pelvic Pain Postoperative Pain Postoperative Pain Retrospective Studies

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (4)

Cited by (4)

References (20)

Cited by (4)

Source provenance

europepmc
last seen: 2026-06-14T06:08:20.186862+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:24:37.768885+00:00
License: CC0 · commercial use OK