Cross-sectional study on cervical cancer and precancerous lesions screening results among eligible women in Dabu County, Meizhou City,Guangdong Province, 2022-2024

Cross-sectional study on cervical cancer and precancerous lesions screening results among eligible women in Dabu County, Meizhou City,Guangdong Province, 2022-2024 | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Cross-sectional study on cervical cancer and precancerous lesions screening results among eligible women in Dabu County, Meizhou City,Guangdong Province, 2022-2024 Qing Lin, Caili Deng, Chunna Liu, Aihua Luo This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6401666/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract This study aims to analyze the detection rates of cervical cancer and precancerous lesions among women aged 35-64 in Dabu County, Meizhou City, Guangdong Province, from 2022 to 2024. The findings are intended to provide a basis for the subsequent implementation of free screening programs and the achievement of the goal to eliminate cervical cancer. Methods: Women who underwent free cervical cancer screening between January 1, 2022, and December 31, 2024, were selected for the study. A retrospective analysis and summary were conducted on the general data of 10,876 married women who received the free screening. The screening for all women included medical history inquiries, routine gynecological examinations, and high-risk Human Papillomavirus（HPV） testing. Those who tested positive for the other 13 high-risk HPV types underwent further cervical cytology tests（ThinPrep Cytologic Test， TCT）. Women who tested positive for HPV types 16 or 18, those with positive results for the other 13 high-risk HPV types plus TCT results of Atypical Squamous Cells of Undetermined Significance （ ASC-US ） or higher, and those suspected of having cervical cancer during gynecological examinations were further examined with colposcopy. Abnormal findings in colposcopy necessitated cervical biopsies under colposcopic guidance for histopathological examination. The research data were aggregated by the Dabu County Maternity and Child Healthcare Hospital, with data sourced from the Guangdong Provincial Maternity and Child Healthcare Information Platform. Result ： This study included 10,876 women who participated in the free cervical cancer screening program in Dabu County from 2022 to 2024. The results revealed: an HPV infection rate of 11.24%, an ASC-US+ detection rate of 6.31% in cervical cytology examinations, a cervical cancer detection rate of 110.33 per 100,000, a precancerous lesion detection rate of 864.29 per 100,000, and an early diagnosis rate of cervical cancer of 91.51%. Conclusion: Cervical cancer screening for women is a crucial method for the early detection of precancerous lesions and cervical cancer. By providing free cervical cancer screening, it is possible to achieve early detection, diagnosis, and intervention for precancerous lesions and cervical cancer among women of appropriate age in relatively low-income rural areas. This approach effectively controls and gradually reduces the incidence of cervical cancer.The incidence of cervical cancer in Dabu County is high, and the situation regarding cervical cancer prevention and control is severe. It is imperative to enhance the efforts of free cervical cancer screening in Dabu County. human papillomavirus cervical cytology tests cervical cancer screening cervical precancerous lesions cervical cancer Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6401666","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":453464634,"identity":"a503ebdf-fa3d-463a-a167-fda4a42a9fdb","order_by":0,"name":"Qing Lin","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAtElEQVRIiWNgGAWjYBAC+/PNBw4k/vsvR4KeG8cSDzxgYzYmQcuBHOODQC2JDUTrYGw4Y3AggYctve94AuOHjzlEaGFmbis4kCDBkzvzzANmyZnbiNDCxnB4w4EEA4ncDTcS2Jh5idHCw5AAdFiCQboB0VokGFKAWkCaiNZiIHEs4UBiwwHDmWceNhPnFwP+5sMffzYckOc7nnzww0ditCDAARKiBqYlgVQdo2AUjIJRMFIAAC7cP4LuKXJYAAAAAElFTkSuQmCC","orcid":"","institution":"Shenzhen Maternity and Child Healthcare Hospital","correspondingAuthor":true,"prefix":"","firstName":"Qing","middleName":"","lastName":"Lin","suffix":""},{"id":453464635,"identity":"f9c59cd9-c4b2-4f5a-ac52-71cc01801cba","order_by":1,"name":"Caili Deng","email":"","orcid":"","institution":"Dabu County Maternity and Child Healthcare Hospital","correspondingAuthor":false,"prefix":"","firstName":"Caili","middleName":"","lastName":"Deng","suffix":""},{"id":453464636,"identity":"64e35560-fc8d-4374-ab08-ebf0c5e74280","order_by":2,"name":"Chunna Liu","email":"","orcid":"","institution":"Dabu County Maternity and Child Healthcare Hospital","correspondingAuthor":false,"prefix":"","firstName":"Chunna","middleName":"","lastName":"Liu","suffix":""},{"id":453464637,"identity":"9b9f76c9-cb62-43b2-947b-e9f1df6380e0","order_by":3,"name":"Aihua Luo","email":"","orcid":"","institution":"Dabu County Maternity and Child Healthcare Hospital","correspondingAuthor":false,"prefix":"","firstName":"Aihua","middleName":"","lastName":"Luo","suffix":""}],"badges":[],"createdAt":"2025-04-08 09:23:38","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-6401666/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-6401666/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":97326232,"identity":"75c525b1-6bc9-4c0d-b9eb-de272b2916c0","added_by":"auto","created_at":"2025-12-03 08:39:28","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":286010,"visible":true,"origin":"","legend":"","description":"","filename":"CrosssectionalstudyoncervicalcancerandprecancerouslesionsscreeningresultsamongeligiblewomeninDabuCountyMeizhouCityGuangdongProvince2022202420250415103806.pdf","url":"https://assets-eu.researchsquare.com/files/rs-6401666/v1_covered_63d114f5-d0fb-44f6-9310-8be73971bbcd.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Cross-sectional study on cervical cancer and precancerous lesions screening results among eligible women in Dabu County, Meizhou City,Guangdong Province, 2022-2024","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"human papillomavirus, cervical cytology tests, cervical cancer screening,cervical precancerous lesions, cervical cancer","lastPublishedDoi":"10.21203/rs.3.rs-6401666/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-6401666/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eThis study aims to analyze the detection rates of cervical cancer and precancerous lesions among women aged 35-64 in Dabu County, Meizhou City, Guangdong Province, from 2022 to 2024. The findings are intended to provide a basis for the subsequent implementation of free screening programs and the achievement of the goal to eliminate cervical cancer.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eMethods: Women who underwent free cervical cancer screening between January 1, 2022, and December 31, 2024, were selected for the study. A retrospective analysis and summary were conducted on the general data of 10,876 married women who received the free screening. The screening for all women included medical history inquiries, routine gynecological examinations, and high-risk Human Papillomavirus（HPV） testing. Those who tested positive for the other 13 high-risk HPV types underwent further cervical cytology tests（ThinPrep Cytologic Test， TCT）. Women who tested positive for HPV types 16 or 18, those with positive results for the other 13 high-risk HPV types plus TCT results of Atypical Squamous Cells of Undetermined Significance （ ASC-US ） or higher, and those suspected of having cervical cancer during gynecological examinations were further examined with colposcopy. Abnormal findings in colposcopy necessitated cervical biopsies under colposcopic guidance for histopathological examination. The research data were aggregated by the Dabu County Maternity and Child Healthcare Hospital, with data sourced from the Guangdong Provincial Maternity and Child Healthcare Information Platform.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eResult ： This study included 10,876 women who participated in the free cervical cancer screening program in Dabu County from 2022 to 2024. The results revealed: an HPV infection rate of 11.24%, an ASC-US+ detection rate of 6.31% in cervical cytology examinations, a cervical cancer detection rate of 110.33 per 100,000, a precancerous lesion detection rate of 864.29 per 100,000, and an early diagnosis rate of cervical cancer of 91.51%.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eConclusion: Cervical cancer screening for women is a crucial method for the early detection of precancerous lesions and cervical cancer. By providing free cervical cancer screening, it is possible to achieve early detection, diagnosis, and intervention for precancerous lesions and cervical cancer among women of appropriate age in relatively low-income rural areas. This approach effectively controls and gradually reduces the incidence of cervical cancer.The incidence of cervical cancer in Dabu County is high, and the situation regarding cervical cancer prevention and control is severe. It is imperative to enhance the efforts of free cervical cancer screening in Dabu County.\u003c/p\u003e","manuscriptTitle":"Cross-sectional study on cervical cancer and precancerous lesions screening results among eligible women in Dabu County, Meizhou City,Guangdong Province, 2022-2024","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-05-08 04:30:19","doi":"10.21203/rs.3.rs-6401666/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"19a558f5-15b9-4bb5-9410-b81bbf522d21","owner":[],"postedDate":"May 8th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2025-12-03T08:38:20+00:00","versionOfRecord":[],"versionCreatedAt":"2025-05-08 04:30:19","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-6401666","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-6401666","identity":"rs-6401666","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}