Mesenchymal stem cells (MSC): Identification, Proliferation and Differentiation
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Abstract
Stem cells have the remarkable potential to develop into many different specialized cells in the body. Serving as a sort of repair system for the body, they can theoretically divide without limit to repletion other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential to either endure a stem cell or become another type of cell with a more specialized function, such as a muscle cell, or a red blood cell, or a brain cell. Mesenchymal stem cells (MSC) are a group of cells present in bone-marrow stroma and the stroma of various organs with the capacity for mesoderm-like cell differentiation into, many types like osteoblasts, adipocytes, and chondrocytes. MSC are being use in the clinic for the treatment of a variety of clinical conditions. Cell-based therapies (CBTs) are quickly taking hold as a revolutionary new approach to treat many human diseases. Among the cells used for therapeutic functions, multipotent mesenchymal stromal cells, also often and imprecisely termed (MSC), are widely used because they are considered clinically safe, unique in their immune-capabilities, easily obtained from adult tissues, and easily developed and restore.
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