Multimodal Imaging of Presumed Dusn Associated with Strongyloides Stercoralis Infection

PURPOSE To report multimodal imaging findings in a case of presumed Diffuse Unilateral Subacute Neuroretinitis (DUSN) associated with Strongyloides stercoralis infection. METHODS Retrospective case report. RESULTS A thirty-eight-year-old woman presented with visual loss of one week’s duration in her left eye. She had a medical history of chronic dermatitis and epigastralgia. Fundoscopic examination revealed diffuse subretinal inflammatory lesions. Optical coherence tomography showed a disruption of the ellipsoid layer and focal thickenings of the retinal pigment epithelium in the macular region, as well as cells in the vitreous cavity. Fundus autofluorescence showed granular hyperautofluorescence in the posterior pole. Fluorescein angiography revealed leakage of the optic disk and pinpoint disperse hyperfluorescent lesions. Serology tests detected Strongyloides stercoralis antibodies and blood count showed eosinophilia. Treatment with Ivermectine resolved both the ophthalmologic abnormalities and the eosinophilia. CONCLUSION DUSN may be associated with Strongyloides stercoralis infection. Inflammatory lesions, if treated early, may resolve without sequelae.