Herlyn-Werner-Wunderlich Syndrome—Timely Diagnosis is Important to Preserve Fertility

Nilgün Güdücü, Güdücü N, Gökçenur Gönenç, Gönenç G, Işçi H, Herman İşçi, Yiğiter AB, Alin Başgül Yiğiter, Dünder I, İlkkan Dünder
Journal of Pediatric and Adolescent Gynecology · 2012 · vol. 25(5) , pp. e111–e112 · doi:10.1016/j.jpag.2012.05.013 · PMID:22841374 · W2073394061
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This paper discusses Herlyn-Werner-Wunderlich Syndrome, emphasizing the importance of timely diagnosis to preserve a patient's fertility.

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Abstract

BackgroundHerlyn-Werner-Wunderlich syndrome is an urogenital malformation with uterus didelphys and obstructed hemivagina with ipsilateral renal agenesis. Most of these patients present after the onset of menstruation. We describe two cases diagnosed too late to prevent the complications.CaseThe first patient presented with acute abdomen one year after the onset of menstruation and had salpingectomy due to pyosalpinx. The blind hemivagina was not recognized and she had severe endometriosis. She underwent hysterectomy 8 years later. The second patient presented with foul smelling vaginal discharge when she was 21 years old. She had a simple vaginal septum resection.Summary and conclusionIn the presence of uterine cavities in a regularly menstruating girl with dysmenorrhea, the presence of both kidneys should be checked. When unilateral renal agenesis and uterus didelphys coexist the first thing that we should remember is to confirm or refute the presence of a blind vagina.

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MeSH descriptors

Hydrocolpos Kidney Urogenital Abnormalities Urogenital Abnormalities Uterus Vagina Abdomen, Acute Adolescent Diagnosis, Differential Female Humans Hydrocolpos Hydrocolpos Hydrocolpos Hysterectomy Kidney Salpingectomy Syndrome Urogenital Abnormalities Uterus

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