Meta-analysis of clinical trials of transcranial magnetic stimulation for chronic pelvic pain syndrome

Mengyang Wang, Chunhua Yang, Rui Xia, Zhengxian Xu, Jun Liu, Yalan Dai, Yuxing Kuang, Xingjie Li, Ziyi Wu, Shangjie Chen, Min Wang, Hongdang Qu
In: Research Square · 2022 · doi:10.21203/rs.3.rs-1508757/v1 · W4281681055
preprint OA: green CC0
📄 Open PDF View on OpenAlex View at publisher

Abstract

Abstract Background: In recent years, repeated transcranial magnetic stimulation (rTMS) has been used in clinical trials for the treatment of chronic pelvic pain syndrome, but its efficacy needs to be further verified.Objectives/Methods: This meta-analysis aimed to evaluate the efficacy and safety of transcranial magnetic stimulation in the treatment of chronic pelvic pain syndrome. Databases of PubMed, the Cochrane Library, Embase, CNKI, VIP, Wanfang, and SinoMed were searched for all clinical trials published before Nov.08.2021. The effect size was evaluated by using the standardized mean difference (SMD) and a 95% confidence interval (CI). Results: We included 7 studies comprising 99 participants. VAS scale was used as the main index of pain intensity, was observed (SMD=0.19, 95%CI -0.07 to 0.42, p=0.13) has no treatment effect. Reduction in depression ,anxiety and symptoms were not find out, there was a significant effect of quality of life (SF-36, SMD= -8.69, 95%CI -12.04 to -5.35, p＜0.00001). No serious adverse events were reported by the included articles.Conclusion: TMS may improve ADL, and long-term interventions of rTMS have a positive impact on pain and mood in patients with CPPS. However, these findings should be interpreted with caution due to the limitations of the included studies.

My notes (saved in your browser only)

Outcome instruments

VAS-pain

Condition tags

chronic_pelvic_pain

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (38)

Source provenance

europepmc
last seen: 2026-05-19T01:45:01.086888+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK