WITHDRAWN: Active Lubrication of Transluminal Medical Instruments

preprint OA: closed
Full text JSON View at publisher

Abstract

Abstract Transluminal minimally invasive surgery uses natural orifices and small incisions to access internal anatomical structures, promoting quicker recovery and reduced morbidity. However, navigating instruments--catheters and endoscopes--through anatomical pathways creates frictional interactions with luminal walls, risking complications such as perforation, poor haptic feedback, and instrument buckling. In this paper, we present a new approach to actively lubricate transluminal instruments and dynamically reduce friction with surrounding tissues. This approach employs ultrasonic vibrations, at the instrument surface, to generate a pressurized fluid layer at the contact interface, lubricating the interface and thereby reducing friction. We implemented this approach in a prototype catheter, which we validated under dry and liquid-lubricated conditions, across rigid and soft interfaces, and along varied anatomical curvatures. In a cardiac catheter use case, active lubrication reduced friction by up to 42% on ex-vivo porcine aorta tissue and 82% on rigid substrates, denoting its potential performance on healthy and calcified tissue, respectively. Thermal imaging confirmed that temperature at the tissue-catheter interface remained within safe limits. Additionally, the system effectively prevented buckling during catheter insertion experiment, further showcasing its potential. By minimizing injury risk and enhancing procedural stability, active lubrication can drastically enhance the safety and efficacy of transluminal interventions.
Full text 10,689 characters · extracted from preprint-html · click to expand
WITHDRAWN: Active Lubrication of Transluminal Medical Instruments | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article WITHDRAWN: Active Lubrication of Transluminal Medical Instruments Mostafa A. Atalla, Jelte Nieuwenhuis, Alan Martin, Xuan Wang, and 5 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6779184/v2 This work is licensed under a CC BY 4.0 License Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Editorial Note The full text of this preprint has been withdrawn by the authors in order to comply with an institutional policy on preprints. Therefore, the authors do not wish this work to be cited as a reference. Editorial notes are used to provide important context regarding the topic of a preprint or to alert readers to potential issues concerning that preprint or a downstream publication associated with it. For more information on editorial notes, see our Editorial Policies . Abstract The full text of this preprint has been withdrawn by the authors in order to comply with an institutional policy on preprints. Therefore, the authors do not wish this work to be cited as a reference. Physical sciences/Engineering/Mechanical engineering Physical sciences/Engineering/Biomedical engineering Health sciences/Medical research/Translational research Full Text Additional Declarations There is NO Competing Interest. Cite Share Download PDF Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6779184","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":468807310,"identity":"d29be22d-34e9-4f82-8bce-31a51fc3f60a","order_by":0,"name":"Mostafa A. Atalla","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA8UlEQVRIie3QMUsDMRjG8eflBW8J3Bqp1U8gRApSsfpZrgi6OHQUBBsJXJdC1/Nb2M1N5R1u8QM4nrvDicuBDiarcNcbO+S/JfDjCQFisa0uYYsaIJtQ5Y/jjUCDyVKRecJ8ZMNFL8KqDzm0XKHB+V3q6P77rJHhijmp6KmdHL/sGFriQmshN7jOZPTgwhPfuggMFFhDyAYyfZT01VLeRZKafjHXB37lZ+zJs4SVTqIMK4g2QvkAYYU3EVEz2TPl7tqTk+Xl1ajwK8W0i5SL9cfnzW26Xzp5byanw9XCof7KJ60EDIQf+FfWDmKxWCzWoz+Ee0yGf4X35gAAAABJRU5ErkJggg==","orcid":"https://orcid.org/0000-0002-0861-8142","institution":"TU Delft","correspondingAuthor":true,"prefix":"","firstName":"Mostafa","middleName":"A.","lastName":"Atalla","suffix":""},{"id":468807311,"identity":"20107d51-1e9e-42f6-95f8-1f5b4ca9c813","order_by":1,"name":"Jelte Nieuwenhuis","email":"","orcid":"","institution":"TU Delft","correspondingAuthor":false,"prefix":"","firstName":"Jelte","middleName":"","lastName":"Nieuwenhuis","suffix":""},{"id":468807312,"identity":"16f5cd38-935b-4046-b390-435aa367c51a","order_by":2,"name":"Alan Martin","email":"","orcid":"","institution":"University of Sheffield","correspondingAuthor":false,"prefix":"","firstName":"Alan","middleName":"","lastName":"Martin","suffix":""},{"id":468807313,"identity":"c6e8a633-b5a8-4395-beaf-4bc47706d54d","order_by":3,"name":"Xuan Wang","email":"","orcid":"","institution":"University of Sheffield","correspondingAuthor":false,"prefix":"","firstName":"Xuan","middleName":"","lastName":"Wang","suffix":""},{"id":468807314,"identity":"66927321-7410-4c2f-aa56-6912f17eb4f9","order_by":4,"name":"Ahranee Canden","email":"","orcid":"","institution":"University of Sheffield","correspondingAuthor":false,"prefix":"","firstName":"Ahranee","middleName":"","lastName":"Canden","suffix":""},{"id":468807315,"identity":"57c71e77-d1fe-4ef6-890e-48fd239999d3","order_by":5,"name":"Matt Carré","email":"","orcid":"","institution":"University of Sheffield","correspondingAuthor":false,"prefix":"","firstName":"Matt","middleName":"","lastName":"Carré","suffix":""},{"id":468807316,"identity":"64009054-e6d5-4ea7-b41a-d74cbef00b81","order_by":6,"name":"Roger Lewis","email":"","orcid":"","institution":"University of Sheffield","correspondingAuthor":false,"prefix":"","firstName":"Roger","middleName":"","lastName":"Lewis","suffix":""},{"id":468807317,"identity":"9175cc98-0d1a-4faa-8b78-77189d39ee5c","order_by":7,"name":"Aimee Sakes","email":"","orcid":"","institution":"TU Delft","correspondingAuthor":false,"prefix":"","firstName":"Aimee","middleName":"","lastName":"Sakes","suffix":""},{"id":468807318,"identity":"873f7739-8aa8-436f-a618-01787effcb9f","order_by":8,"name":"Michael Wiertlewski","email":"","orcid":"","institution":"Delft University of Technology","correspondingAuthor":false,"prefix":"","firstName":"Michael","middleName":"","lastName":"Wiertlewski","suffix":""}],"badges":[],"createdAt":"2025-05-29 20:00:13","currentVersionCode":2,"declarations":"","doi":"10.21203/rs.3.rs-6779184/v2","doiUrl":"https://doi.org/10.21203/rs.3.rs-6779184/v2","draftVersion":[],"editorialEvents":[],"editorialNote":"The full text of this preprint has been withdrawn by the authors in order to comply with an institutional policy on preprints. Therefore, the authors do not wish this work to be cited as a reference. ","failedWorkflow":false,"files":[],"financialInterests":"There is \u003cb\u003eNO\u003c/b\u003e Competing Interest.","formattedTitle":"WITHDRAWN: Active Lubrication of Transluminal Medical Instruments","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":true,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":false,"isWithdrawnOrRetracted":true,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"","lastPublishedDoi":"10.21203/rs.3.rs-6779184/v2","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-6779184/v2","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"The full text of this preprint has been withdrawn by the authors in order to comply with an institutional policy on preprints. Therefore, the authors do not wish this work to be cited as a reference. ","manuscriptTitle":"WITHDRAWN: Active Lubrication of Transluminal Medical Instruments","msid":"","msnumber":"","nonDraftVersions":[{"code":2,"date":"2025-06-09 19:55:58","doi":"10.21203/rs.3.rs-6779184/v2","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}},{"code":1,"date":"2025-06-06 03:57:44","doi":"10.21203/rs.3.rs-6779184/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"ce0ee3f9-48b7-4a3d-9853-342b1a4fe53f","owner":[],"postedDate":"June 9th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[{"id":49774088,"name":"Physical sciences/Engineering/Mechanical engineering"},{"id":49774089,"name":"Physical sciences/Engineering/Biomedical engineering"},{"id":49774090,"name":"Health sciences/Medical research/Translational research"}],"tags":[],"updatedAt":"2025-06-09T19:55:58+00:00","versionOfRecord":[],"versionCreatedAt":"2025-06-09 19:55:58","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v2","identity":"rs-6779184","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-6779184","identity":"rs-6779184","version":["v2"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: preprint-html

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2025) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.

Source provenance

europepmc
last seen: 2026-05-20T01:45:00.602351+00:00