Successful Operation Following Neoadjuvant Immunotherapy Combined with Chemotherapy for Right Aortic Arch with Esophageal Cancer: A Case Report

Abstract Background Right aortic arch (AAA) with esophageal cancer is a kind of rare case. Tumor shrinkage after neoadjuvant immunotherapy combined with chemotherapy and subsequently successful excision of the esophageal tumor under minimally invasive surgery are reported for this case in this paper.Case presentation The patient was a 50-year-old man who was diagnosed with AAA and esophageal cancer with a clinical stage of c-T3N1M0, stage III. Because Computed tomography(CT) indicated a larger volume of the tumor with signs of outward invasion, along with vascular malformations, neoadjuvant immunotherapy combined with neoadjuvant chemotherapy was given. After 3 cycles of neoadjuvant therapy, this patient achieved a fully clinical symptom remission, and re-examination result of chest CT showed tumor shrinkage, so a minimally invasive surgery was provided to remove the tumor. Following the surgery, immunotherapy and chemotherapy were continued.Conclusion For locally advanced esophageal cancer with vascular malformations, neoadjuvant therapy is a good treatment option. If achieving downstaging, the tumor would be well removed just with a minimally invasive surgery.