The Clinical Pharmacology of Piroxicam
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Abstract
Piroxicam, a potent inhibitor of prostaglandins, is effective and well-tolerated in the treatment of primary dysmenorrhea. A single 40 mg dose has been shown to rapidly reduce the uterine hypercontractility of primary dysmenorrhea. In clinical trials vs placebo, piroxicam in a dose of 40 mg once daily for two days followed by 20 mg once daily thereafter demonstrated superior efficacy. In more than 1,400 piroxicam-treated menstrual cycles and more than 200 placebo-controlled cycles, a similar incidence of side effects-7% and 8.4% respectively-was observed.
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Cites (2)
- The uterine contractility index: A research and diagnostic tool in dysmenorrhea 1983
- PIROXICAM IN THE TREATMENT OF PRIMARY DYSMENORRHEA 1985
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0
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