A RETROSPECTIVE REAL-WORLD STUDY OF PHADIATOP USE AND ITS IMPACT ON REFERRALS TO ALLERGY SPECIALISTS IN A HEALTH AREA

A RETROSPECTIVE REAL-WORLD STUDY OF PHADIATOP USE AND ITS IMPACT ON REFERRALS TO ALLERGY SPECIALISTS IN A HEALTH AREA | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 27 March 2025 V1 Latest version Share on A RETROSPECTIVE REAL-WORLD STUDY OF PHADIATOP USE AND ITS IMPACT ON REFERRALS TO ALLERGY SPECIALISTS IN A HEALTH AREA Authors : Inês Costa Farinha , Milagros Lázaro-Sastre [email protected] , Rosita Castillo Loja , Adelaida Núñez Cabrera , Nerea Otero Fernández 0009-0003-0981-4545 , Elena Laffond Yges , Sonia Arriba-Méndez , and Ignacio Davila 0000-0001-8485-5513 Authors Info & Affiliations https://doi.org/10.22541/au.174304331.17262897/v1 256 views 127 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract not-yet-known not-yet-known not-yet-known unknown Introduction and Objectives: ImmunoCAP Phadiatop (Thermo Fisher Scientific) is an in vitro assay detecting IgE antibodies against a balanced mixture of common inhalant allergens, serving as a first level screening tool for sensitization in patients with suspected respiratory allergies guiding subsequent management. This study aimed to evaluate test results, the impact on clinical decision-making, and its role in managing allergic condition. Materials and Methods: A real-world retrospective observational study was conducted in a tertiary hospital allergy department (June 2021–June 2023). Data were collected using the Modulab Laboratory Information System (Werfen, Spain) and stored in a dissociated database. The Ethics Committee of Salamanca approved the study protocol. Phadiatop values above 0.35 PAU/l were considered positive. In case of repeated samples, the first was selected. Variables analyzed included test results, patient demographics, requesting departments, and allergy referrals. Results: The study included 596 patients (median age 46, 64.1% female). Of these, 12.6% were under 18 years old. Most patients (95.8%) were referred from primary care, with 83.1% originating from urban areas. Positive results occurred in 37.9% (median IgE 7.81 PAU/l). Most positive patients resided in urban areas (82.3%), were aged < 18 years (p=0.001), and were male (p59 (26.3%) presented mainly negative results (82.2%). Of the positive cases, 31.4% were referred to an allergist, with higher Phadiatop values increasing referrals (p=0.001). Conclusions: Phadiatop was mainly utilized in primary care. One-third of patients tested positive; of those, only one-third were referred to allergists, with higher Phadiatop values increasing referral rates. Positivity was higher in males and younger people. Supplementary Material File (evaluation of phadiatop utilization and its impact on allergy referral 25.03.25_allergy.docx) Download 117.17 KB Information & Authors Information Version history V1 Version 1 27 March 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords allergy diagnosis epidemiology ige Authors Affiliations Inês Costa Farinha Unidade Local de Saude de Coimbra View all articles by this author Milagros Lázaro-Sastre [email protected] Hospital Universitario de Salamanca View all articles by this author Rosita Castillo Loja Hospital Universitario de Salamanca View all articles by this author Adelaida Núñez Cabrera Hospital Universitario de Salamanca View all articles by this author Nerea Otero Fernández 0009-0003-0981-4545 Hospital Universitario de Salamanca View all articles by this author Elena Laffond Yges Hospital Universitario de Salamanca View all articles by this author Sonia Arriba-Méndez Hospital Universitario de Salamanca View all articles by this author Ignacio Davila 0000-0001-8485-5513 Hospital Universitario de Salamanca View all articles by this author Metrics & Citations Metrics Article Usage 256 views 127 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Inês Costa Farinha, Milagros Lázaro-Sastre, Rosita Castillo Loja, et al. A RETROSPECTIVE REAL-WORLD STUDY OF PHADIATOP USE AND ITS IMPACT ON REFERRALS TO ALLERGY SPECIALISTS IN A HEALTH AREA. Authorea . 27 March 2025. DOI: https://doi.org/10.22541/au.174304331.17262897/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . 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