Detection of Epo and VEGF mRNA in endometriotic tissues using hybridization in situ

Cai Guoqing; Chen Biliang; Fan Yang; Ma Xiangdong; Wang Detang; Guo Huiling

Detection of Epo and VEGF mRNA in endometriotic tissues using hybridization in situ

Cai Guoqing, Chen Biliang, Fan Yang, Ma Xiangdong, Wang Detang, Guo Huiling

Journal of the Fourth Military Medical University · 2004

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Abstract

The expression of mRNA of Epo and VEGF in endometriosis was 3.08+-0.48 and 2.95+-0.43, respectively, which was significantly higher than those in normal endometrium (P<0.001). The expression of Epo mRNA was closely correlated with that of VEGF mRNA (C=0.733, P<0.001) and the expression of mRNA of Epo was closely correlated with the endometriosis^staging of American Fertility Society (P<0.01). The increased expression of mRNA of Epo and VEGF may play some important roles in the pathogenesis of endometiosis.

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