Long-Term Outcome of Laparoscopic Presacral Neurectomy for the Treatment of Central Pelvic Pain Attributed to Endometriosis

In Brief Objective To evaluate the long-term pain reduction achieved by laparoscopic presacral neurectomy. Methods One hundred seventy-six women with median (range) age 30 (18–45) years underwent presacral neurectomy combined with excision and vaporization of endometriotic lesions and were observed, using structured questionnaires, for up to 72 months postoperatively. The study included a convenience sample of the first 100 questionnaires returned. Forty of the women were studied for 12–23 months, and 60 for 24–72 months. The main outcome measures were reduction of pelvic pain, dysmenorrhea, and dyspareunia after surgery. Results Pelvic pain, dysmenorrhea, and dyspareunia were reportedly reduced by more than 50% in 74, 61, and 55 patients, respectively, more than 72 months after laparoscopic presacral neurectomy. More than 50% reduction in pelvic pain was reported by 69.8%, 77.3%, 71.4%, and 84.6% of the patients, respectively, with endometriosis stages I-IV, using the revised classification of the American Fertility Society. Comparatively, more than 50% reduction in dysmenorrhea was reported by 52.8% of the patients with stage I endometriosis, 68.2% with stage II, 71.4% with stage III, and 69.2% with stage IV. Reduction of dyspareunia by more than 50% was reported by 54.7% of the patients with stage I endometriosis, 50.0% with stage II, 28.6% with stage III, and 61.5% with stage IV. Conclusion Long-term outcome of laparoscopic presacral neurectomy is satisfactory in the majority of patients. The stage of endometriosis is not related directly to the degree of pain improvement achieved. Most patients experience long-term pain reduction after laparoscopic presacral neurectomy.