The efficacy of ultrasound-guided treatment of ovarian endometriosis cysts: A meta-analysis

Qian Zhang, Zhang Q, Jing Zhao, Zhao J, Feng W, Wei Feng, Su F, Fangfei Su, Xianquan Shi, Shi X, Zhang L, Lina Zhang
African journal of reproductive health · 2026 · pp. 115–123 · doi:10.29063/ajrh2026/v30i7.10 · PMID:41979432
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⚙ AI-generated summary by claude@2026-06, 2026-06-10 ⓘ

This meta-analysis of ten studies found ultrasound-guided treatment of ovarian endometriosis cysts showed higher effectiveness, shorter operation times, fewer adverse reactions, and improved hormonal profiles compared to laparoscopic cyst resection.

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⚙ AI-generated deep summary by claude@2026-07, 2026-07-09 · read from full text ⓘ

This paper is a meta-analysis evaluating the efficacy of ultrasound-guided treatments for ovarian endometriosis cysts, drawing together studies that used ultrasound guidance for interventional approaches such as aspiration and sclerotherapy (including ethanol) and related ultrasound-guided strategies. It summarizes outcomes across included study reports but is limited by the heterogeneity and non-uniformity typical of pooled interventional evidence, with a quality appraisal referenced via the Newcastle-Ottawa Scale for non-randomized studies. The meta-analysis focuses on ovarian endometriotic cyst treatment efficacy using ultrasound-guided methods, though the provided text does not state specific effect sizes in the excerpt. This paper is centrally about endometriosis — it synthesizes evidence on ultrasound-guided treatment outcomes for ovarian endometriosis cysts.

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Abstract

The purpose of this meta-analysis was to systematically assess the efficacy of ultrasound-guided therapy of ovarian endometriosis cyst (OEC). Several databases were searched to gather published studies on the efficacy of ultrasound-guided treatment of OEC. The period of publication of the included studies was January 1, 2000 to December 31, 2020. Two researchers screened the literature and extracted data independently. The publication bias of the obtained studies was assessed. The obtain data was analyzed by a meta-analysis. Ten literatures ware included in this meta-analysis, including 2379 patients in the control group (laparoscopic cyst resection) as well as 1244 in the study group (ultrasound-guided interventional therapy). In contrast to the control group, the study group had higher treatment effectiveness rate, shorter operative duration, lower incidence of adverse reactions, higher luteinizing hormone level as well as lower follicle-stimulating hormone level. We conclude that ultrasound-guided treatment of OEC is conducive to improving the clinical treatment effect, reducing the effective rate of treatment, shortening the operative duration, decreasing the incidence of postoperative adverse reactions, increasing the luteinizing hormone level and decreasing the folliclestimulating hormone level, which can effectively protect female's ovarian function, and is worthy of promotion and application.
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The efficacy of ultrasound-guided treatment of ovarian endometriosis cysts: A meta-analysis Abstract Full Text: PDFReferences Nisolle M. O-071 The ovarian endometriotic cyst. Human Reproduction. 2021; 36(S1): Krasnopolskaya Ksenia V, Popov Alexander A, Fedorov Anton A , Ershova Irina Y. Algorithm for overcoming infertility secondary to ovarian endometriotic cyst: a view of a reproductive specialist and a surgeon. Obstetrics and Gynecology 2020(11): 78-84. Junmei W , Chengxia Q. Clinical Effect of Gonadotropin-Releasing Hormone Combined with Laparoscopy on Patients with Ovarian Endometriotic Cyst. Doctor. 2019 Throwba HP, Unnikrishnan L, Pangath M, Vasudevan K, Jayaraman S, Li M, Iyaswamy A, Palaniyandi K , Gnanasampanthapandian D. The epigenetic correlation among ovarian cancer, endometriosis and PCOS: A review. Crit Rev Oncol Hematol. 2022; 180103852. Farkas AH, Abumusa H , Rossiter B. Structural Gynecological Disease: Fibroids, Endometriosis, Ovarian Cysts. Med Clin North Am. 2023; 107(2): 317-328. Graupera B, Pascual M, Alcazar J, Pedrero C, Hereter L, Barri‐Soldevila P, Rodríguez L, Guerrier S. OC15.05: Prevalence of deep infiltrating endometriosis in patients with endometriotic ovarian cyst. Ultrasound in Obstetrics & Gynecology 2018; 5237. Gupta SS, Patil SB , Deshmukh SV. A rare case of bilateral mucinous cystadenocarcinoma of ovary mimicking endometriotic ovarian cyst on radiology. IP Journal of Diagnostic Pathology and Oncology. 2020(1): De Maio A, Alfieri G, Mattone M, Ghanouni P , Napoli A. High-Intensity Focused Ultrasound Surgery for Tumor Ablation: A Review of Current Applications. Radiology Imaging cancer. 2024; 6(1): e230074. Giorlandino C, Taramanni C, Muzii L, Santillo E, Nanni C ,Vizzone A. Ultrasound-guided aspiration of ovarian endometriotic cysts. Int J Gynaecol Obstet. 1993; 43(1): 41-44. Baojun L. Clinical Application of Ultrasound Diagnosis in Gynecological Acute Abdomen. Foreign Edition: Medicine and Health. 2022; 4104-107. Wells G. The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Non-Randomised Studies in Meta-Analyses. Symposium on Systematic Reviews: Beyond the Basics. 2014. Hui Z. Efficacy evaluation of ultrasound-guided interventional therapy for ovarian endometriotic cysts. The Medical Forum. 2019; 23(5): 673-675. Zhao G , Minghui L. Efficacy evaluation of ultrasound-guided interventional therapy for ovarian endometriotic cysts. Chinese Journal of Medical Physics. 2018; 35(3): 292-295. Haixia W. Analysis of Therapeutic Effect of Ultrasound-Guided Interventional Therapy for Ovarian Endometriotic Cyst. Journal of Mathematical Medicine. 2020; 30(04): 549-550. Dong W. Effect of ultrasound intervention therapy on ovarian endometriomas and analysis of related factors of postoperative recurrence. Journal of Huaihai Medicine. 2020; 38(05): 449-452. Holsbeke CV, Calster BV, Melis GB, Testa A, Guerriero S, Fruscio R, Lissoni AA, Czekierdowski A , Savelli，L. OC05.05: External validation of "old" and new mathematical models to distinguish between benign and malignant adnexal masses. Ultrasound in Obstetrics & Gynecology 2009; 34(S1): 8. Toshimitsu K, Hisanori M, Mitsuhiro M, Shuichi O, Hiroyuki F , Ikuo S. Reproductive performance after ultrasound-guided transvaginal ethanol sclerotherapy for ovarian endometriotic cysts. European Journal of Obstetrics and Gynecology. 2002; 105(1): 39-43. Lulu W, Xiaoqiu D, Xiaohui S , Siming W. Ultrasound-guided interventional therapy for recurrent ovarian chocolate cysts. Ultrasound in Medicine & Biology. 2011; 37(10): 1596-1602. Xiaoyun W , Yun X. Gestrinone combined with ultrasound‐guided aspiration and ethanol injection for treatment of chocolate cyst of ovary. J Obstet Gynaecol Res 2015; 41(5): 712-716. Fei D, Li Y , Sui G. Clinical study of ultrasound-guided puncture lauromacrogol sclerosis in the treatment of ovarian endometriosis cyst. In: AIP Conference Proceedings 2018, AIP Publishing. Zhihui C, Weiming W, Junrong S, Yi-Juan L, Youju M , Zhang J. Comparison of ultrasound interventional and laparoscopic surgeries for ovarian cyst pediculotorsion. Journal of Acute Disease 2016; 5(6): 458-46122. Ayse A, Tsui-Lien M, Tamer S, Chen-Hsuan W, B, G, Hiroshi O, Masayuki F, Hiroki M, Yoshihito Y, Robert J K , Ie-Ming S. Loss of ARID1A expression is an early molecular event in tumor progression from ovarian endometriotic cyst to clear cell and endometrioid carcinoma. Int J Gynecol Cancer. 2012; 22(8): 1310-1315. Tabarrai M , Kasraei R. The report of a treatment of recurrent ovarian endometriotic cyst by using therapeutic methods of traditional Persian Medicine. 2017 Hsieh CL, Shiau CS, Lo LM, Hsieh TT , Chang MY. Effectiveness of ultrasound-guided aspiration and sclerotherapy with 95% ethanol for treatment of recurrent ovarian endometriomas. Fertil Steril. 2009; 91(6): 2709-2713. Zhao L, Deng Y, Wei Q, Chen J , Zhao C. Comparison of ultrasound-guided high-intensity focused ultrasound ablation and surgery for abdominal wall endometriosis. Int J Hyperthermia. 2018; 35(1): 528-533. Koike T, Minakami H, Motoyama M, Ogawa S, Fujiwara H , Sato I. Reproductive performance after ultrasound-guided transvaginal ethanol sclerotherapy for ovarian endometriotic cysts. Eur J Obstet Gynecol Reprod Biol. 2002; 105(1): 39. Wang Y, Wang W, Wang L, Wang J ,Tang J. Ultrasound-guided high-intensity focused ultrasound treatment for abdominal wall endometriosis: preliminary results. Eur J Radiol. 2011; 79(1): 56-59 Refbacks - There are currently no refbacks.

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endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

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