SYNTHESIS OF 21-CHLORODANAZOL AND ITS △~6-ANALOGUE
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Abstract
Synthesis was undertaken of 21-chloro-danazol (Ⅳa) and 21-chloro-6-dehydro-danazol (Ⅳb). The binding ability of these compounds to progesterone receptor were examined and were found to be less active than danazol.Compound (Ⅳa) showed significant activity for eary pregnancy termination effect in Sprague-Dawley rats.
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- openalex
- last seen: 2026-05-10T10:02:18.307429+00:00
License: CC0
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