An Experimental Study of Mechanism in Treatment for Endometriosis with Xiao Chai Hu Tang in Rats

To explore the mechanism of Xiao Chai Hu Tang in treatment for endometriosis in rats, the rat model of endometriosis was established.Using immunohistochemistry method, Fas and Caspase-3 protein expression in endometrium and endometriotic tissue of each group were observed.The results showed that in the group treated with Xiao Chai Hu Tang, the protein expressions of Fas and Caspase-3 in endometriotic tissue were higher than those in endometrium, while in the control group,the result was just opposite. The difference was not obvious in the group treated with Danazol.The higher levels of the protein expression of Fas in endometriotic tissue may related to the pathogenesis of the endometriosis.The mechanism of Xiao Chai Hu Tang treatment may be partly to increase apoptosis in endometriotic tissue.