EG-VEGF/Prokineticin 2 receptor antagonists
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This patent describes compositions and methods for treating endometrial diseases like endometriosis by inhibiting EG-VEGF or its receptor, including diagnostic tests for uterine receptivity.
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Abstract
Treatment and prevention of endometrial disease, e.g. endometriosis or carcinoma, by inhibiting endocrine gland vascular endothelial growth factor, also diagnosis A composition that contains, as active agent (A), an endocrine gland vascular endothelial growth factor (EG-VEGF) nucleic acid, polypeptide or antisense nucleic acid, antibody against EG-VEGF or its receptor (EG-VEGF-R), or EG-VEGF-R antisense nucleic acid, is useful for the treatment or prevention of endometrial diseases Independent claims are also included for the following: (1) method for detecting uterine receptivity by determining the amount of EG-VEGF polypeptide and/or nucleic acid, using the new composition; or (2) test system for identifying antagonists (B) of EG-VEGF-R.
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- europepmc
- last seen: 2026-07-16T06:15:11.481547+00:00