Dominant and recessive effects of the selected SNPs in HOTAIR gene between Taiwanese endometriosis patients and controls.

Cherry Yin-Yi Chang (7224650), Chung-Chen Tseng (10262915), Ming-Tsung Lai (493834), An-Jen Chiang (688755), Lun-Chien Lo (10262918), Chih-Mei Chen (309456), Man-Ju Yen (10262921), Li Sun (4624), Li Yang (6520), Tritium Hwang (10262924), Fuu-Jen Tsai (230856), Jim Jinn-Chyuan Sheu (7326185)
2021 · doi:10.1371/journal.pone.0248168.t002 · W6885858777
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This study analyzed the dominant and recessive effects of selected single nucleotide polymorphisms in the HOTAIR gene to compare Taiwanese endometriosis patients with healthy controls.

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This study investigated the genetic influence of single nucleotide polymorphisms within the HOTAIR gene on its thermostability during endometriosis progression. Researchers analyzed Taiwanese patients with endometriosis and compared them to healthy controls to identify dominant and recessive SNP effects associated with the disease. The findings highlighted specific genetic variations in HOTAIR that correlate with altered RNA stability and disease presence in the studied population. This paper is centrally about endometriosis, focusing on the role of HOTAIR gene variants as potential biomarkers or contributors to pathogenesis.

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Abstract

Dominant and recessive effects of the selected SNPs in HOTAIR gene between Taiwanese endometriosis patients and controls.
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Genetic impacts on thermostability of onco-lncRNA HOTAIR during the development and progression of endometriosis Table 2 Dominant and recessive effects of the selected SNPs in HOTAIR gene between Taiwanese endometriosis patients and controls. Skip to main content Advertisement Browse Subject Areas ? Click through the PLOS taxonomy to find articles in your field. For more information about PLOS Subject Areas, click here. Dominant and recessive effects of the selected SNPs in HOTAIR gene between Taiwanese endometriosis patients and controls.

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endometriosis

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