Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study

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This study aimed to investigate the prevalence of mental health problems and their associated factors in patients with asymptomatic or mildly symptomatic in the hospitel in Thailand. Methods Mental health problems were evaluated using the Depression, Anxiety, and Stress Scale - 21 items, and Patient Health Questionnaire-9. The prevalence of mental health problems was presented by frequency and percentage. McNemar's test was used to compare the prevalence of mental health problems between day 1 and day 7. Binary logistic regression was used to identify potential predictors of mental health problems. Results A total of 186 participants (68.3% female; mean age = 37.21 years (SD 13.66) were recruited. The depression, anxiety, and stress rate on day 1 of admission was 26.9%, 32.3% and 25.8%, respectively. Having mild COVID-19 symptoms was a significantly associated factor with anxiety (OR=2.69, 95%CI: 1.05-6.89) and stress (OR=4.53, 95%CI: 1.32-15.55). Conclusions There was a high rate of mental health problems in COVID-19 patients. Detecting and managing mental health problems should be considered standard care for COVID-19 patients." } { "@context": "http://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": "1", "item": { "@id": "https://f1000research.com/", "name": "Home" } }, { "@type": "ListItem", "position": "2", "item": { "@id": "https://f1000research.com/browse/articles", "name": "Browse" } }, { "@type": "ListItem", "position": "3", "item": { "@id": "https://f1000research.com/articles/11-1089", "name": "Mental health problems of asymptomatic or mildly symptomatic COVID-19..." } } ] } Home Browse Mental health problems of asymptomatic or mildly symptomatic COVID-19... ALL Metrics - Views Downloads Get PDF Get XML Cite How to cite this article Kerdcharoen N, Kirdchok P, Wonglertwisawakorn C et al. Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.12688/f1000research.125998.4 ) NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article. Close Copy Citation Details Export Export Citation Sciwheel EndNote Ref. Manager Bibtex ProCite Sente EXPORT Select a format first Track Share ▬ ✚ Research Article Revised Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] Nitchawan Kerdcharoen https://orcid.org/0000-0003-2302-9618 1 , Pantri Kirdchok 1 , Chayut Wonglertwisawakorn 1 , Yingrat Naviganuntana 1 , Nongnuch Polruamngern 1 , Chotiman Chinvararak https://orcid.org/0000-0001-7087-2355 1 Nitchawan Kerdcharoen https://orcid.org/0000-0003-2302-9618 1 , Pantri Kirdchok 1 , [...] Chayut Wonglertwisawakorn 1 , Yingrat Naviganuntana 1 , Nongnuch Polruamngern 1 , Chotiman Chinvararak https://orcid.org/0000-0001-7087-2355 1 PUBLISHED 01 Apr 2025 Author details Author details 1 Department of Psychiatry, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, 10300, Thailand Nitchawan Kerdcharoen Roles: Conceptualization, Funding Acquisition, Methodology, Project Administration, Resources, Supervision, Validation, Writing – Original Draft Preparation, Writing – Review & Editing Pantri Kirdchok Roles: Conceptualization, Formal Analysis, Investigation, Methodology, Validation, Writing – Original Draft Preparation, Writing – Review & Editing Chayut Wonglertwisawakorn Roles: Conceptualization, Investigation, Methodology, Writing – Original Draft Preparation, Writing – Review & Editing Yingrat Naviganuntana Roles: Conceptualization, Investigation, Methodology, Writing – Original Draft Preparation, Writing – Review & Editing Nongnuch Polruamngern Roles: Data Curation, Funding Acquisition, Project Administration, Resources Chotiman Chinvararak Roles: Conceptualization, Formal Analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing OPEN PEER REVIEW DETAILS REVIEWER STATUS This article is included in the Emerging Diseases and Outbreaks gateway. This article is included in the Global Public Health gateway. Abstract Background There is evidence that patients with COVID-19 have a higher prevalence of mental health problems than the normal population. This study aimed to investigate the prevalence of mental health problems and their associated factors in patients with asymptomatic or mildly symptomatic in the hospitel in Thailand. Methods Mental health problems were evaluated using the Depression, Anxiety, and Stress Scale - 21 items, and Patient Health Questionnaire-9. The prevalence of mental health problems was presented by frequency and percentage. McNemar's test was used to compare the prevalence of mental health problems between day 1 and day 7. Binary logistic regression was used to identify potential predictors of mental health problems. Results A total of 186 participants (68.3% female; mean age = 37.21 years (SD 13.66) were recruited. The depression, anxiety, and stress rate on day 1 of admission was 26.9%, 32.3% and 25.8%, respectively. Having mild COVID-19 symptoms was a significantly associated factor with anxiety (OR=2.69, 95%CI: 1.05-6.89) and stress (OR=4.53, 95%CI: 1.32-15.55). Conclusions There was a high rate of mental health problems in COVID-19 patients. Detecting and managing mental health problems should be considered standard care for COVID-19 patients. READ ALL READ LESS Keywords Mental health problems; COVID-19; Hospitel; Thailand Corresponding Author(s) Chotiman Chinvararak ( [email protected] ) Close Corresponding author: Chotiman Chinvararak Competing interests: No competing interests were disclosed. Grant information: This study received a grant from Navamindradhiraj University Research Fund. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Copyright: © 2025 Kerdcharoen N et al . This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. How to cite: Kerdcharoen N, Kirdchok P, Wonglertwisawakorn C et al. Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.12688/f1000research.125998.4 ) First published: 22 Sep 2022, 11 :1089 ( https://doi.org/10.12688/f1000research.125998.1 ) Latest published: 01 Apr 2025, 11 :1089 ( https://doi.org/10.12688/f1000research.125998.4 ) Revised Amendments from Version 3 We added a name to the Acknowledgements. We added a name to the Acknowledgements. See the authors' detailed response to the review by Sorawit Wainipitapong READ REVIEWER RESPONSES Introduction Since the World Health Organization announced the emergency statement regarding the pandemic of novel coronavirus disease 2019 (COVID-19) on 30 January 2020, Thailand, like other countries, has to face the rise of new cases of COVID-19 . The number of positive COVID-19 cases exceeded the health system's capacity. However, at the beginning of the pandemic, Thailand did not have a home isolation policy and stated that all patients would be under the medical team's care. Therefore, the Thai government set up the “hospitel”, a new type of health care facility. 1 The term “hospitel” is the compound noun from the “hospital” and “hotel”. It is a new type of health care facility specialised for COVID-19 patients who are asymptomatic or have only mild symptoms. A hospitel is organised and run by the hotel and medical staffs from an affiliated public hospital. The team includes general practitioners, nurses and paramedics. Patients in hospitel are monitored regularly and are quarantined for seven days or until they have negative COVID-19 test results. 1 Hence, hospitels also aim to prevent the spread of COVID-19 in the community. 1 Although patients are regularly monitored for physical complications, mental health problems, especially stress adjustment, may be under-recognised. The meta-analysis study by Liu et al. , 2021 found that anxiety symptoms and depression rates in COVID-19 patients were 32% and 27.6%, respectively. 2 Moreover, insomnia was found to have a prevalence of 30.30%. While the study in Thailand by Lerthattasilp et al. , 2020 showed that the prevalence of depression was found to be 22.5%, whilst the anxiety rate was 30%, and the stress rate was 20%. 3 The study by Lerthattasilp et al. was conducted in a field hospital that has a similar concept of caring to “hospitel”. 3 This data demonstrated that patients with COVID-19 are more likely to suffer mental health problems than the normal population. In addition, early studies revealed that the female gender, physical symptoms related to COVID-19, duration of hospitalisation, and a history of psychiatric disorders were associated factors to mental health problems. 3 – 7 The objective of the present study was to investigate the prevalence of mental health problems, including depression, anxiety and stress, as well as their associated factors in patients with asymptomatic or mildly symptomatic in the hospitel in Thailand, which is under the supervision of the Faculty of Medicine Vajira Hospital. The Faculty of Medicine Vajira Hospital is responsible for caring for COVID-19 patients from the Thonburi district in Bangkok. We hypothesise that the prevalence of mental health problems is likely to be high on day 1 at admission and will decline after 7 days. However, despite to the new outbreak of COVID-19 globally, there are still limited studies on mental health problems. Recognising this concern is essential to the Thai public health sector in order to implement appropriate measures to tackle mental health problems related to COVID-19 infection. Methods Ethics and consent We obtained approval from the Ethical Committee of the Institutional Review Board of the Faculty of Medicine Vajira Hospital on July 2 nd , 2021 (COA no. 106/2564). Before starting the survey, all participants were informed of the study's objectives, method, and provided written informed consent. Study design, setting and participants We employed a cross-sectional descriptive study based on STROBE guidelines. 8 The sample size was calculated following the Cochrane formula. 9 As the number of COVID-19 patients (N) admitted to the hospitel between July and September 2021 was 250, the sample size was estimated by p = 0.198 according to the study by Jeong et al. , 2019. 7 Using alpha at 0.05 and error (d) at 0.05, the required sample size was 124. 186 asymptomatic or mildly symptomatic COVID-19 patients, according to COVID-19 treatment guidelines by the National Institutes of Health (NIH ), aged 18 years and older were recruited by purposive sampling in-person when the participant was initially admitted to the hospitel under the supervision of the Faculty of Medicine Vajira Hospital from July to September 2021. Patients who could not use the internet were excluded from this study. Data collection The study instruments consisted of four questionnaires: 1) demographic characteristics including sex, age, education level, employment status, financial status, and living status; 2) clinical characteristics including severity of COVID-19, duration of COVID-19 infection, duration admitted in the hospitel, referring status, admission status, history of medical and mental disorders and perceived psychological support while in the hospitel, which is a close-ended question (yes or no); 3) the Depression, Anxiety, and Stress Scale - 21 items (DASS-21); and 4) Patient Health Questionnaire-9 (PHQ-9) would performed if participants had moderate to severe severity from DASS-21 score in any domains. In addition, we collected participants' data on day 1 and day 7 of admission by Google form. DASS-21 consists of three domains; each domain comprises seven items, and the depression, anxiety, and stress scores are calculated by summing. Then, the severity of each part is categorised into normal, mild, moderate, severe and extremely severe. The Cronbach's alpha coefficient of the DASS-21 Thai version is 0.75 reflecting good internal consistency. 10 , 11 PHQ-9 Thai version has a total of 9 depressive questions. The total score of PHQ-9 is classified into normal (0–6), mild (7–12), moderate (13–18), and severe (≥19). The sensitivity and specificity of PHQ-9 are 84% and 77%, respectively, to detect depression. 12 , 13 Statistical analyses Data were analysed using SPSS software (version 28.0; IBM, Chicago, IL, USA). The prevalence of mental health problems was presented by frequency and percentage. McNemar's test was used to compare the prevalence of mental health problems between day 1 and day 7. In addition, binary logistic regression (odds ratio [OR] and 95% confidence interval [CI]) was used to identify potential predictors of depression, anxiety and stress. P<0.05 was considered statistically significant. Results Of 186 participants recruited in this study, they had a mean age of 37.21 years old (SD 13.66). The majority of participants were female (68.3%), single (54.8%), had an undergraduate degree (44.1%), employed (49.5%), and were living with family (59.7%) ( Table 1 ). Table 1. Demographics of patients (N=186). Variables N (%) Age (years), Mean±SD 37.21±13.66 (Min-Max) (18-75) Sex Male 59 (31.7) Female 127 (68.3) Race: Thai 184 (98.9) Marital status Single 102 (54.8) Married 69 (37.1) Divorced or Separated 11 (5.9) Widow 4 (2.2) Educational level Lower than primary school 5 (2.7) Primary school 25 (13.4) Junior high school 44 (23.7) Senior high school 15 (8.1) Undergraduate university 82 (44.1) Postgraduate university 15 (8.1) Occupation None 33 (17.7) Government official 45 (24.2) Self-employed 16 (8.6) Employee 92 (49.5) Income per month (Thai baht) 0-5,000 23 (12.4) 5,001-10,000 28 (15.1) 10,001-15,000 37 (19.9) 15,001-20,000 32 (17.2) 20,001-25,000 12 (6.5) >25,000 54 (29.0) Living status Living alone 23 (12.4) Living with friends 13 (7.0) Living with a partner 39 (21.0) Living with family 111 (59.7) Family history of Mental disorder 9 (4.8) Table 2 demonstrates the clinical characteristics of the patients. Approximately 16% of participants had at least one underlying medical illness. Only 1.1% of participants had an underlying mental disorder. In addition, around 80% of participants had mild COVID-19 symptoms, and the symptoms lasted at least 7 days. The median duration of hospitel admission was 12 days (IQR 10-13). Most participants were admitted alone (86.6%), and eventually, they could be discharged from the hospitel after 7 days of admission. Interestingly, around 90% of participants perceived that they were provided psychological support while in the hospitel. Table 2. Clinical characteristics of patients (N=186). Variables N (%) Underlying medical disease 30 (16.1) Diabetes mellitus 6 (3.2) Hyperlipidaemia 10 (5.4) Hypertension 20 (10.8) Others 5 (2.7) Underlying mental disorder 2 (1.1) Depression 1 (0.5) Anxiety 1 (0.5) COVID-19 symptom Asymptomatic 35 (18.8) Mild 151 (81.2) Duration with COVID-19 Asymptomatic 22 (11.8) <7 days 35 (18.8) ≥7 days 129 (69.4) Duration of hospitalisation (days) Median (IQR) 0 (0-0) (Min-Max) (0-12) Duration of hospitel admission (days) Median (IQR) 12 (10-13) (Min-Max) (2-14) Admission status Alone 161 (86.6) With family 25 (13.4) Family members diagnosed COVID-19 Median (IQR) 1 (0-3) (Min-Max) (0-11) Referring status Discharge 164 (88.2) Refer from hospital 19 (10.2) Refer to hospital 3 (1.6) Perceived psychological support No 18 (9.7) Yes 168 (90.3) Regarding the prevalence of mental health problems ( Table 3 ), the depression, anxiety, and stress rates were 26.9%, 32.3% and 25.8%, respectively, on day 1 of hospitel admission. The most common level of depression measured by PHQ-9 was mild severity. However, after 7 days of admission, the depression, anxiety, and stress rates decreased to 18.3%, 17.2% and 12.9%, respectively. This difference in the proportion of mental health problems between day 1 and day 7 was statistically significant (P<0.05) ( Figure 1 ). Table 3. Prevalence of mental health problems on day 1 and day 7 (N = 186). Mental health problems Day 1 Day 7 P-value a N (%) N (%) Depression assessed by DASS-21 Normal 136 (73.1) 152 (81.7) 0.014 * Mild to severe 50 (26.9) 34 (18.3) Anxiety Normal 126 (67.7) 154 (82.8) <0.001 ** Mild to severe 60 (32.3) 32 (17.2) Stress Normal 138 (74.2) 162 (87.1) <0.001 ** Mild to severe 48 (25.8) 24 (12.9) Depression assessed by PHQ-9, (n = 31) Normal 15 (48.4) - - Mild 12 (38.7) - - Moderate 3 (9.7) - - Severe 1 (3.2) - - a McNemar's test. * P<0.05. ** P<0.01. Figure 1. Prevalence of mental health problems on day 1 and day 7. The results of binary logistic regression analysis revealed that having mild COVID-19 symptoms was a significantly associated factor with anxiety (OR=2.69, 95%CI: 1.05-6.89) and stress (OR=4.53, 95%CI: 1.32-15.55). In contrast, other factors were not associated with depression, anxiety and stress (P>0.05) ( Table 4 ). Table 4. Factors associated with mental health problems analysed by binary logistic regression. Factors Depression Anxiety Stress OR 95%CI P-value OR 95%CI P-value OR 95%CI P-value Age (years) 1.00 (0.98-1.02) 0.928 1.00 (0.98-1.02) 0.923 0.98 (0.95-1.00) 0.081 Sex Male 1.15 (0.58-2.30) 0.686 1.55 (0.81-2.97) 0.183 1.61 (0.81-3.19) 0.176 Female 1.00 Reference 1.00 Reference 1.00 Reference Marital status Single 1.00 Reference 1.00 Reference 1.00 Reference Married 1.26 (0.63-2.50) 0.515 1.15 (0.60-2.20) 0.685 0.51 (0.24-1.07) 0.076 Widow/Divorced/Separated 1.54 (0.48-4.93) 0.467 1.53 (0.50-4.66) 0.457 1.60 (0.52-4.89) 0.410 Education level Primary school or lower 1.37 (0.57-3.30) 0.489 1.02 (0.43-2.42) 0.972 0.94 (0.38-2.37) 0.900 High school 0.85 (0.40-1.80) 0.670 0.89 (0.44-1.79) 0.747 0.73 (0.34-1.57) 0.422 Undergraduate university or higher 1.00 Reference 1.00 Reference 1.00 Reference Occupation Government official 1.00 Reference 1.00 Reference 1.00 Reference Self-employed/Employee 1.86 (0.78-4.45) 0.162 1.75 (0.80-3.83) 0.164 1.41 (0.62-3.19) 0.411 None 2.31 (0.81-6.63) 0.119 1.34 (0.49-3.68) 0.565 0.94 (0.32-2.81) 0.915 Income (baht) 0-15,000 1.24 (0.56-2.75) 0.600 1.17 (0.56-2.43) 0.679 0.90 (0.41-1.96) 0.782 15,001-25,000 1.81 (0.74-4.43) 0.193 1.23 (0.52-2.89) 0.637 1.20 (0.49-2.91) 0.690 >25,000 1.00 Reference 1.00 Reference 1.00 Reference Living status Living alone 0.57 (0.18-1.81) 0.338 0.49 (0.17-1.43) 0.193 0.60 (0.19-1.90) 0.380 Living with friends 1.69 (0.51-5.57) 0.390 1.52 (0.48-4.84) 0.477 1.77 (0.54-5.84) 0.350 Living with a partner 1.06 (0.47-2.39) 0.887 0.53 (0.23-1.23) 0.141 0.98 (0.42-2.25) 0.953 Living with family 1.00 Reference 1.00 Reference 1.00 Reference Underlying medical disease 0.64 (0.24-1.66) 0.356 0.47 (0.18-1.23) 0.123 0.53 (0.19-1.46) 0.218 Underlying mental disorder - - NA - - NA 2.92 (0.18-47.53) 0.453 Family history of mental 2.28 (0.59-8.85) 0.234 2.77 (0.72-10.73) 0.140 2.42 (0.62-9.41) 0.203 COVID-19 symptom Asymptomatic 1.00 Reference 1.00 Reference 1.00 Reference Mild 2.55 (0.93-6.99) 0.069 2.69 (1.05-6.89) 0.039 * 4.53 (1.32-15.55) 0.03 * Admission status Alone 1.00 Reference 1.00 Reference 1.00 Reference With family 1.65 (0.68-4.01) 0.272 1.48 (0.62-3.52) 0.375 0.90 (0.34-2.39) 0.824 Family members diagnosed with COVID-19 1.04 (0.90-1.20) 0.616 1.03 (0.89-1.18) 0.692 0.94 (0.80-1.11) 0.481 Perceived psychological support No 2.40 (0.89-6.48) 0.084 1.38 (0.51-3.76) 0.528 1.12 (0.38-3.32) 0.841 Yes 1.00 Reference 1.00 Reference 1.00 Reference * P<0.05. Discussion To the best of our knowledge, this is the first study to explore the prevalence of mental health problems among patients with COVID-19 in the hospitel in Thailand. The prevalence of depression was 26.9%, anxiety was 32.3%, and stress was 25.8% in patients with asymptomatic or mild COVID-19 symptoms at day 1 of their stay at the hospitel under the Faculty of Medicine Vajira Hospital supervision. Compared to the meta-analysis study from multinational countries, including China, the United States, Japan, India, and Turkey, the depression and anxiety rates had a similar trend (27.6 % vs 26.9 for depression and 32.6% vs 32.3% for anxiety). 2 On the contrary, the stress rate in this study was relatively lower than in the study at the Thammasat University field hospital (30% vs 25.8%). 3 Although we also used the DASS-21, the same questionnaire, the prevalence of stress in this study might have been lower since the study at the Thammasat University field hospital had more moderate to severe COVID-19 cases. 3 In addition, the context of hospitels and field hospitals were different in many ways; for example, the privacy and facility of hospitels might be better than field hospitals. The mental health problems rate declined significantly on day 7 of admission (P<0.05). The potential explanation may be that most patients can adjust to acute stress over time and with perceived psychological support. 14 , 15 Moreover, the medical team at the hospitel always provide basic psychoeducation via a leaflet and video clip about coping with stress. 16 The high-risk cases of mental disorders would then be referred to psychologists or psychiatrists. In this study, mild COVID-19 symptoms was the only factor associated with anxiety and stress. This could be a helpful predictor of psychological screening problems in patients admitted to hospitel. However, unlike prior studies, we could not find the association between the female gender, duration of hospitalisation, and a history of psychiatric disorders and mental health problems. This could be because there were few patients with psychiatric disorders in this study. Additionally, we did not collect data on the detail of the physical symptoms of COVID-19. We are aware of some limitations of the present study. First, we can only indicate associated factors, not causal relationships, due to the descriptive design. Secondly, we included only asymptomatic and mild symptoms, which may not represent all COVID-19 patients. Finally, the mental health problems in this study were assessed by online self-reporting questionnaires, which could demonstrate only symptoms, not disorders and patients who could not use the internet were excluded. Thus, patients with high-risk mental disorders should be further evaluated by psychiatrists or clinical psychologists. Future research should investigate the prevalence of posttraumatic stress disorder (PTSD), which could be occurred following COVID-19 as a traumatic stressor. 17 In addition, psychological intervention to prevent stress-related illnesses or psychological distress 18 should be performed. Conclusions The prevalence of mental health problems in COVID-19 patients was common, especially on the first day of admission. However, it declined on the 7th day after admission. In addition, having mild symptomatic COVID-19 infection was an associated factor with anxiety and stress. Therefore, detecting and managing mental health problems should be considered standard care for COVID-19 patients. Data availability Underlying data figshare: Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A Cross-Sectional Study, https://doi.org/10.6084/m9.figshare.21108790.v1 . 19 This project contains the following extended data: • Hospitel Data.sav (anonymised responses in spss) Extended data figshare: Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A Cross-Sectional Study, https://doi.org/10.6084/m9.figshare.21108790.v1 . 19 This project contains the following extended data: • Demographic data record-Hospitel.docx (blank English copy of the demographic and clinical characteristics questionnaire used in this study) Data are available under the terms of the Creative Commons Zero “No rights reserved” data waiver (CC0 1.0 Public domain dedication). Acknowledgements The authors acknowledge all study participants and would like to thank Anucha Kamson for his assistance with the statistical analysis and Kwanpond Traivaranon for her assistance with data curation. References 1. Tangcharoensathien V, Sachdev S, Viriyathorn S, et al. : Universal access to comprehensive COVID-19 services for everyone in Thailand. BMJ Glob. Health. 2022; 7 (6): e009281. PubMed Abstract | Publisher Full Text 2. Liu X, Zhu M, Zhang R, et al. : Public mental health problems during COVID-19 pandemic: a large-scale meta-analysis of the evidence. Transl. Psychiatry. 2021; 11 (1): 384. PubMed Abstract | Publisher Full Text 3. Lerthattasilp T, Kosulwit K, Phanasathit M, et al. : Psychological impacts on patients with COVID-19 in a Thai field hospital. Arch. Clin. Psychiatry. 2020; 47 (6): 215–217. Publisher Full Text 4. Li J, Yang Z, Zhang J, et al. : The psychological symptoms of patients with mild symptoms of coronavirus disease (2019) in China: A cross-sectional study. J. Adv. Nurs. 2021; 77 (4): 1813–1824. PubMed Abstract | Publisher Full Text 5. Ismael F, Bizario J, Battagin T, et al. : Post-infection depressive, anxiety and posttraumatic stress symptoms: A prospective cohort study in patients with mild COVID-19. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 2021; 111 : 110341. PubMed Abstract | Publisher Full Text 6. Leung T, Chan A, Chan EW, et al. : Short- and potential long-term adverse health outcomes of COVID-19: a rapid review. Emerg. Microbes Infect. 2020; 9 (1): 2190–2199. PubMed Abstract | Publisher Full Text 7. Jeong SJ, Chung WS, Sohn Y, et al. : Clinical characteristics and online mental health care of asymptomatic or mildly symptomatic patients with coronavirus disease 2019. PLoS One. 2020; 15 (11): e0242130. PubMed Abstract | Publisher Full Text 8. von Elm E , Altman DG, Egger M, et al. : The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. J. Clin. Epidemiol. 2008; 61 (4): 344–349. Publisher Full Text 9. Wayne WD: Biostatistics: a foundation for analysis in the health sciences. 6th ed.New York: Wiley & Sons; 1995. 10. Lovibond SH, Lovibond PF: Manual for the Depression Anxiety Stress Scales. 2nd. ed.Sydney: Psychology Foundation; 1995. 11. Oei TP, Sawang S, Goh YW, et al. : Using the Depression Anxiety Stress Scale 21 (DASS-21) across cultures. Int. J. Psychol. 2013; 48 (6): 1018–1029. PubMed Abstract | Publisher Full Text 12. Kroenke K, Spitzer RL, Williams JB: The PHQ-9: validity of a brief depression severity measure. J. Gen. Intern. Med. 2001; 16 (9): 606–613. PubMed Abstract | Publisher Full Text | Free Full Text 13. Lotrakul M, Sumrithe S, Saipanish R: Reliability and validity of the Thai version of the PHQ-9. BMC Psychiatry. 2008; 8 : 46. PubMed Abstract | Publisher Full Text 14. Babić R, Babić M, Rastović P, et al. : Resilience in Health and Illness. Psychiatr. Danub. 2020; 32 (Suppl 2): 226–232. PubMed Abstract 15. Lakey B, Orehek E, Hain KL, et al. : Enacted support's links to negative affect and perceived support are more consistent with theory when social influences are isolated from trait influences. Personal. Soc. Psychol. Bull. 2010; 36 (1): 132–142. PubMed Abstract | Publisher Full Text 16. Brooks SK, Webster RK, Smith LE, et al. : The psychological impact of quarantine and how to reduce it: rapid review of the evidence. Lancet (London, England). 2020; 395 (10227): 912–920. PubMed Abstract | Publisher Full Text 17. Yuan K, Gong YM, Liu L, et al. : Prevalence of posttraumatic stress disorder after infectious disease pandemics in the twenty-first century, including COVID-19: a meta-analysis and systematic review. Mol. Psychiatry. 2021; 26 (9): 4982–4998. PubMed Abstract | Publisher Full Text 18. Life event, stress and illness: The psychological impact of quarantine and how to reduce it: rapid review of the evidence. Lancet. 395 (10227): 912–920. PubMed Abstract | Publisher Full Text 19. Chinvararak C: Demegraphic data record-Hospitel.docx. figshare. Dataset.2022. Publisher Full Text Comments on this article Comments (0) Version 4 VERSION 4 PUBLISHED 22 Sep 2022 ADD YOUR COMMENT Comment Author details Author details 1 Department of Psychiatry, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, 10300, Thailand Nitchawan Kerdcharoen Roles: Conceptualization, Funding Acquisition, Methodology, Project Administration, Resources, Supervision, Validation, Writing – Original Draft Preparation, Writing – Review & Editing Pantri Kirdchok Roles: Conceptualization, Formal Analysis, Investigation, Methodology, Validation, Writing – Original Draft Preparation, Writing – Review & Editing Chayut Wonglertwisawakorn Roles: Conceptualization, Investigation, Methodology, Writing – Original Draft Preparation, Writing – Review & Editing Yingrat Naviganuntana Roles: Conceptualization, Investigation, Methodology, Writing – Original Draft Preparation, Writing – Review & Editing Nongnuch Polruamngern Roles: Data Curation, Funding Acquisition, Project Administration, Resources Chotiman Chinvararak Roles: Conceptualization, Formal Analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Competing interests No competing interests were disclosed. Grant information This study received a grant from Navamindradhiraj University Research Fund. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Article Versions (4) version 4 Revised Published: 01 Apr 2025, 11:1089 https://doi.org/10.12688/f1000research.125998.4 version 3 Revised Published: 14 Mar 2025, 11:1089 https://doi.org/10.12688/f1000research.125998.3 version 2 Revised Published: 07 Oct 2022, 11:1089 https://doi.org/10.12688/f1000research.125998.2 version 1 Published: 22 Sep 2022, 11:1089 https://doi.org/10.12688/f1000research.125998.1 Copyright © 2025 Kerdcharoen N et al . This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Download Export To Sciwheel Bibtex EndNote ProCite Ref. Manager (RIS) Sente metrics Views Downloads F1000Research - - PubMed Central info_outline Data from PMC are received and updated monthly. - - Citations open_in_new 0 open_in_new 0 open_in_new SEE MORE DETAILS CITE how to cite this article Kerdcharoen N, Kirdchok P, Wonglertwisawakorn C et al. Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.12688/f1000research.125998.4 ) NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS track receive updates on this article Track an article to receive email alerts on any updates to this article. TRACK THIS ARTICLE Share Open Peer Review Current Reviewer Status: ? Key to Reviewer Statuses VIEW HIDE Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Version 2 VERSION 2 PUBLISHED 07 Oct 2022 Revised Views 0 Cite How to cite this report: Mottershead R. Reviewer Report For: Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.5256/f1000research.139474.r159686 ) The direct URL for this report is: https://f1000research.com/articles/11-1089/v2#referee-response-159686 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 17 Jan 2023 Richard Mottershead , Ras Al Khaimah College of Nursing, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates Approved VIEWS 0 https://doi.org/10.5256/f1000research.139474.r159686 Thank you for allowing me to review your relevant and topical paper. The paper provides a useful insight into the impact of Covid-19 not only on the physical aspect but the mental health implications of the virus and wider pandemic ... Continue reading READ ALL Thank you for allowing me to review your relevant and topical paper. The paper provides a useful insight into the impact of Covid-19 not only on the physical aspect but the mental health implications of the virus and wider pandemic fall-out. The authors introduce a rich data stream that provides a useful insight into care in Thailand which can be then examined by researchers globally based on the methods and methodology set down within this article. The recommendations of ensuring mental health care for those having been diagnosed with Covid-19 is an intervention which would provide holistic care for our communities and would benefit our wider national healthcare strategies. Is the work clearly and accurately presented and does it cite the current literature? Yes Is the study design appropriate and is the work technically sound? Yes Are sufficient details of methods and analysis provided to allow replication by others? Yes If applicable, is the statistical analysis and its interpretation appropriate? Yes Are all the source data underlying the results available to ensure full reproducibility? Yes Are the conclusions drawn adequately supported by the results? Yes Competing Interests: No competing interests were disclosed. Reviewer Expertise: I am a researcher who is actively involved in health and social care and applied research for disenfranchised groups and areas of need within our society. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Mottershead R. Reviewer Report For: Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.5256/f1000research.139474.r159686 ) The direct URL for this report is: https://f1000research.com/articles/11-1089/v2#referee-response-159686 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Respond or Comment COMMENT ON THIS REPORT Views 0 Cite How to cite this report: Wainipitapong S. Reviewer Report For: Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.5256/f1000research.139474.r152674 ) The direct URL for this report is: https://f1000research.com/articles/11-1089/v2#referee-response-152674 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 10 Oct 2022 Sorawit Wainipitapong , Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand Approved VIEWS 0 https://doi.org/10.5256/f1000research.139474.r152674 The authors responded to all suggestions with a satisfactory revision. Thank you for ... Continue reading READ ALL The authors responded to all suggestions with a satisfactory revision. Thank you for revising according to my comments and I have no further queries or suggestions. Competing Interests: No competing interests were disclosed. Reviewer Expertise: Psychiatry I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Wainipitapong S. Reviewer Report For: Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.5256/f1000research.139474.r152674 ) The direct URL for this report is: https://f1000research.com/articles/11-1089/v2#referee-response-152674 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Respond or Comment COMMENT ON THIS REPORT Version 1 VERSION 1 PUBLISHED 22 Sep 2022 Views 0 Cite How to cite this report: Wainipitapong S. Reviewer Report For: Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.5256/f1000research.138366.r151293 ) The direct URL for this report is: https://f1000research.com/articles/11-1089/v1#referee-response-151293 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 26 Sep 2022 Sorawit Wainipitapong , Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand Approved with Reservations VIEWS 0 https://doi.org/10.5256/f1000research.138366.r151293 Thank you for the opportunity to review this article. The report was well written and organized. Hereby, please find my suggestion for this work to become better suitable for indexing: Some general profiles ... Continue reading READ ALL Thank you for the opportunity to review this article. The report was well written and organized. Hereby, please find my suggestion for this work to become better suitable for indexing: Some general profiles of study location, Vajira Hospital, should be stated. For example, is it located in the metropolitan, urbanized, or regional area? Readers would gain benefit for generalizability regarding mental health-related profiles and conditions. Are previous mental disorders enrolled in the exclusion criteria? How did the authors measure ‘perceived psychological support while in the hospitel’? Please clarify. Please kindly check the psychometric properties of PHQ-9 Thai version. Because the categorized severity of depression and the cut-off score of two cited references are not similar, the authors are suggested to carefully use the interpretation of this screening tool and specify the cut-off score used in the study. Table 1 – Does ‘income’ refer to ‘income per month’? Table 2 – Should ‘asymptomatic’ in the ‘Duration with COVID-19’ section be placed in the proper position? Figure 1 – P-value could also be shown in the figure for it was mentioned in the text. Table 4 – Please check the indent used in the table (i.e. Widow/Divorced/Separated and Educational level). Table 4 – Please check the spelling ‘P<0.0.’ in the end of the table. Compared to the finding from another Thai field hospital, the authors might provide additional discussions regarding the location or uniqueness of the hospital besides the severity of COVID-19. Congratulations to all authors. They have done great work and I enjoyed reading this manuscript a lot. Is the work clearly and accurately presented and does it cite the current literature? Yes Is the study design appropriate and is the work technically sound? Yes Are sufficient details of methods and analysis provided to allow replication by others? Yes If applicable, is the statistical analysis and its interpretation appropriate? Partly Are all the source data underlying the results available to ensure full reproducibility? Yes Are the conclusions drawn adequately supported by the results? Yes Competing Interests: No competing interests were disclosed. Reviewer Expertise: Psychiatry I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Wainipitapong S. Reviewer Report For: Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.5256/f1000research.138366.r151293 ) The direct URL for this report is: https://f1000research.com/articles/11-1089/v1#referee-response-151293 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Author Response 21 Oct 2022 Chotiman Chinvararak , Department of Psychiatry, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, 10300, Thailand 21 Oct 2022 Author Response Thank you very much for your review. We will try to address all your comments and improve them in version 2 of this paper. 1. Vajira hospital is located in ... Continue reading Thank you very much for your review. We will try to address all your comments and improve them in version 2 of this paper. 1. Vajira hospital is located in Bangkok and is responsible for caring for COVID-19 patients, especially those from the Thonburi district. 2. We did not exclude participants with previous mental disorders. There were 2 participants with preexisting mental disorders (shown in Table 2). 3. We used close-ended question (yes or no) to measure perceived psychological support while in the hospitel. We will update this information in version 2 of this paper. 4. We used the classification of depression (PHQ-9 Thai version) following reference number 13. 5. Yes, it refers to income per month. We will add this detail in version 2 of this paper. 6. We will change the position of "asymptomatic" in version 2 of this paper. 7. We will demonstrate P-value in Figure 1. 8. We will check the indent used in Table 1. 9. We will correct this mistake. The phrase is P<0.05. 10. We will discuss this issue (location of the hospitel) in version 2 of this paper. Thank you very much for your review. We will try to address all your comments and improve them in version 2 of this paper. 1. Vajira hospital is located in Bangkok and is responsible for caring for COVID-19 patients, especially those from the Thonburi district. 2. We did not exclude participants with previous mental disorders. There were 2 participants with preexisting mental disorders (shown in Table 2). 3. We used close-ended question (yes or no) to measure perceived psychological support while in the hospitel. We will update this information in version 2 of this paper. 4. We used the classification of depression (PHQ-9 Thai version) following reference number 13. 5. Yes, it refers to income per month. We will add this detail in version 2 of this paper. 6. We will change the position of "asymptomatic" in version 2 of this paper. 7. We will demonstrate P-value in Figure 1. 8. We will check the indent used in Table 1. 9. We will correct this mistake. The phrase is P<0.05. 10. We will discuss this issue (location of the hospitel) in version 2 of this paper. Competing Interests: No competing interests were disclosed. Close Report a concern Respond or Comment COMMENTS ON THIS REPORT Author Response 21 Oct 2022 Chotiman Chinvararak , Department of Psychiatry, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, 10300, Thailand 21 Oct 2022 Author Response Thank you very much for your review. We will try to address all your comments and improve them in version 2 of this paper. 1. Vajira hospital is located in ... Continue reading Thank you very much for your review. We will try to address all your comments and improve them in version 2 of this paper. 1. Vajira hospital is located in Bangkok and is responsible for caring for COVID-19 patients, especially those from the Thonburi district. 2. We did not exclude participants with previous mental disorders. There were 2 participants with preexisting mental disorders (shown in Table 2). 3. We used close-ended question (yes or no) to measure perceived psychological support while in the hospitel. We will update this information in version 2 of this paper. 4. We used the classification of depression (PHQ-9 Thai version) following reference number 13. 5. Yes, it refers to income per month. We will add this detail in version 2 of this paper. 6. We will change the position of "asymptomatic" in version 2 of this paper. 7. We will demonstrate P-value in Figure 1. 8. We will check the indent used in Table 1. 9. We will correct this mistake. The phrase is P<0.05. 10. We will discuss this issue (location of the hospitel) in version 2 of this paper. Thank you very much for your review. We will try to address all your comments and improve them in version 2 of this paper. 1. Vajira hospital is located in Bangkok and is responsible for caring for COVID-19 patients, especially those from the Thonburi district. 2. We did not exclude participants with previous mental disorders. There were 2 participants with preexisting mental disorders (shown in Table 2). 3. We used close-ended question (yes or no) to measure perceived psychological support while in the hospitel. We will update this information in version 2 of this paper. 4. We used the classification of depression (PHQ-9 Thai version) following reference number 13. 5. Yes, it refers to income per month. We will add this detail in version 2 of this paper. 6. We will change the position of "asymptomatic" in version 2 of this paper. 7. We will demonstrate P-value in Figure 1. 8. We will check the indent used in Table 1. 9. We will correct this mistake. The phrase is P<0.05. 10. We will discuss this issue (location of the hospitel) in version 2 of this paper. Competing Interests: No competing interests were disclosed. Close Report a concern COMMENT ON THIS REPORT Comments on this article Comments (0) Version 4 VERSION 4 PUBLISHED 22 Sep 2022 ADD YOUR COMMENT Comment keyboard_arrow_left keyboard_arrow_right Open Peer Review Reviewer Status info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Reviewer Reports Invited Reviewers 1 2 Version 4 (revision) 01 Apr 25 Version 3 (revision) 14 Mar 25 Version 2 (revision) 07 Oct 22 read read Version 1 22 Sep 22 read Sorawit Wainipitapong , Chulalongkorn University, Bangkok, Thailand Richard Mottershead , RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates Comments on this article All Comments (0) Add a comment Sign up for content alerts Sign Up You are now signed up to receive this alert Browse by related subjects keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2023 Mottershead R. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 17 Jan 2023 | for Version 2 Richard Mottershead , Ras Al Khaimah College of Nursing, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates 0 Views copyright © 2023 Mottershead R. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (0) Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Thank you for allowing me to review your relevant and topical paper. The paper provides a useful insight into the impact of Covid-19 not only on the physical aspect but the mental health implications of the virus and wider pandemic fall-out. The authors introduce a rich data stream that provides a useful insight into care in Thailand which can be then examined by researchers globally based on the methods and methodology set down within this article. The recommendations of ensuring mental health care for those having been diagnosed with Covid-19 is an intervention which would provide holistic care for our communities and would benefit our wider national healthcare strategies. Is the work clearly and accurately presented and does it cite the current literature? Yes Is the study design appropriate and is the work technically sound? Yes Are sufficient details of methods and analysis provided to allow replication by others? Yes If applicable, is the statistical analysis and its interpretation appropriate? Yes Are all the source data underlying the results available to ensure full reproducibility? Yes Are the conclusions drawn adequately supported by the results? Yes Competing Interests No competing interests were disclosed. Reviewer Expertise I am a researcher who is actively involved in health and social care and applied research for disenfranchised groups and areas of need within our society. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. reply Respond to this report Responses (0) Mottershead R. Peer Review Report For: Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.5256/f1000research.139474.r159686) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/11-1089/v2#referee-response-159686 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2022 Wainipitapong S. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 10 Oct 2022 | for Version 2 Sorawit Wainipitapong , Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand 0 Views copyright © 2022 Wainipitapong S. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (0) Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions The authors responded to all suggestions with a satisfactory revision. Thank you for revising according to my comments and I have no further queries or suggestions. Competing Interests No competing interests were disclosed. Reviewer Expertise Psychiatry I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. reply Respond to this report Responses (0) Wainipitapong S. Peer Review Report For: Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.5256/f1000research.139474.r152674) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/11-1089/v2#referee-response-152674 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2022 Wainipitapong S. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 26 Sep 2022 | for Version 1 Sorawit Wainipitapong , Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand 0 Views copyright © 2022 Wainipitapong S. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (1) Approved With Reservations info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Thank you for the opportunity to review this article. The report was well written and organized. Hereby, please find my suggestion for this work to become better suitable for indexing: Some general profiles of study location, Vajira Hospital, should be stated. For example, is it located in the metropolitan, urbanized, or regional area? Readers would gain benefit for generalizability regarding mental health-related profiles and conditions. Are previous mental disorders enrolled in the exclusion criteria? How did the authors measure ‘perceived psychological support while in the hospitel’? Please clarify. Please kindly check the psychometric properties of PHQ-9 Thai version. Because the categorized severity of depression and the cut-off score of two cited references are not similar, the authors are suggested to carefully use the interpretation of this screening tool and specify the cut-off score used in the study. Table 1 – Does ‘income’ refer to ‘income per month’? Table 2 – Should ‘asymptomatic’ in the ‘Duration with COVID-19’ section be placed in the proper position? Figure 1 – P-value could also be shown in the figure for it was mentioned in the text. Table 4 – Please check the indent used in the table (i.e. Widow/Divorced/Separated and Educational level). Table 4 – Please check the spelling ‘P<0.0.’ in the end of the table. Compared to the finding from another Thai field hospital, the authors might provide additional discussions regarding the location or uniqueness of the hospital besides the severity of COVID-19. Congratulations to all authors. They have done great work and I enjoyed reading this manuscript a lot. Is the work clearly and accurately presented and does it cite the current literature? Yes Is the study design appropriate and is the work technically sound? Yes Are sufficient details of methods and analysis provided to allow replication by others? Yes If applicable, is the statistical analysis and its interpretation appropriate? Partly Are all the source data underlying the results available to ensure full reproducibility? Yes Are the conclusions drawn adequately supported by the results? Yes Competing Interests No competing interests were disclosed. Reviewer Expertise Psychiatry I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. reply Respond to this report Responses (1) Author Response 21 Oct 2022 Chotiman Chinvararak, Department of Psychiatry, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, 10300, Thailand Thank you very much for your review. We will try to address all your comments and improve them in version 2 of this paper. 1. Vajira hospital is located in Bangkok and is responsible for caring for COVID-19 patients, especially those from the Thonburi district. 2. We did not exclude participants with previous mental disorders. There were 2 participants with preexisting mental disorders (shown in Table 2). 3. We used close-ended question (yes or no) to measure perceived psychological support while in the hospitel. We will update this information in version 2 of this paper. 4. We used the classification of depression (PHQ-9 Thai version) following reference number 13. 5. Yes, it refers to income per month. We will add this detail in version 2 of this paper. 6. We will change the position of "asymptomatic" in version 2 of this paper. 7. We will demonstrate P-value in Figure 1. 8. We will check the indent used in Table 1. 9. We will correct this mistake. The phrase is P<0.05. 10. We will discuss this issue (location of the hospitel) in version 2 of this paper. View more View less Competing Interests No competing interests were disclosed. reply Respond Report a concern Wainipitapong S. Peer Review Report For: Mental health problems of asymptomatic or mildly symptomatic COVID-19 patients in hospitel in Thailand: A cross-sectional study [version 4; peer review: 2 approved] . F1000Research 2025, 11 :1089 ( https://doi.org/10.5256/f1000research.138366.r151293) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/11-1089/v1#referee-response-151293 Alongside their report, reviewers assign a status to the article: Approved - the paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations - A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. 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