[Our clinical experience in treating endometriosis genitalis externa with the preparation Danoval].

Akusherstvo i ginekologiia · 1993 · vol. 32(3) , pp. 69–70 · PMID:8037331 · W2417803515
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Abstract

By means of the serum level of estradiol and the vaginal smear indexes the antigonadotropic activity of the preparation Danoval (2-3-isoxasol-17-ethinyltestosterone) is indirectly evaluated on 15 infertility patients with laparoscopic proved endometriosis. After 5 month's course of treatment with 400 mg daily the level of estradiol decreased from 1.54 to 0.31 nmol/l, IA from 20.8 to 10.4 and IP from 32 to 17.3. The side effects are slight and descend from the pharmacological properties of the preparation. Two patients became pregnant in three months after the treatment.

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Condition tags

endometriosisinfertility

MeSH descriptors

Adnexal Diseases Danazol Endometriosis Adnexal Diseases Adnexal Diseases Adult Danazol Danazol Drug Evaluation Endometriosis Endometriosis Estradiol Estradiol Female Humans

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