[Usefulness of ultrasound endometrium thickness measurement in diagnosis of endometrium pathology in women with abnormal peri- and postmenopausal bleeding].

In: Ginekologia polska · 2009 · vol. 80(7) , pp. 503–7 · PMID:19697813 · W83472966
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Ultrasound measurement of endometrial thickness did not sufficiently improve endometrial pathology diagnosis in women with abnormal bleeding, though a 9 mm cutoff showed promise for excluding cancer.

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The study evaluated whether transvaginal ultrasound measurement of endometrial thickness could help diagnose endometrial pathology in 182 women presenting with abnormal peri- and postmenopausal bleeding, with all participants undergoing endometrial sampling and histologic classification into six groups. The authors reported broad overlap in measured endometrial thickness across groups, with the highest maximal and average values in the carcinoma group, and statistically significant differences in average thickness between carcinoma and hyperplasia versus other groups. Using ultrasound, they proposed a cutoff of 9 mm to exclude endometrial cancer, but concluded that thickness measurement alone was not sufficient to improve diagnostic effectiveness for endometrial pathology in this setting. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

OBJECTIVE: Aim of the study was to assess the usefulness of ultrasound endometrial thickness measurement in the diagnosis of endometrial pathology in women with abnormal peri- and postmenopausal bleeding. MATERIAL AND METHODS: Material included 182 patients whose endometrium sample was obtained for analysis. Patients were divided into six groups according to histological findings. RESULTS: Correlation between thickness of endometrium and histological diagnostic was sought. Wide and partially covered range of endometrium thickness were found in the observed groups. In carcinoma group the highest were maximal and average values. The difference in average thickness of endometrium in carcinoma and hyperplasia groups when compared to the remaining groups proved to be statistically significant A value of cut down ultrasound measured endometrial thickness to exclude endometrial cancer was 9 mm. CONCLUSION: Ultrasound measurement of endometrial thickness is not sufficient to increase effectiveness of endometrial pathology diagnosis in women with abnormal peri- and postmenopausal bleeding.
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Abstract

Abstract Objective: Aim of the study was to assess the usefulness of ultrasound endometrial thickness measurement in the diagnosis of endometrial pathology in women with abnormal peri- and postmenopausal bleeding. Material and methods: Material included 182 patients whose endometrium sample was obtained for analysis. Patients were divided into six groups according to histological findings. Results: Correlation between thickness of endometrium and histological diagnostic was sought. Wide and partially covered range of endometrium thickness were found in the observed groups. In carcinoma group the highest were maximal and average values. The difference in average thickness of endometrium in carcinoma and hyperplasia groups when compared to the remaining groups proved to be statistically significant. A value of cut down ultrasound measured endometrial thickness to exclude endometrial cancer was 9mm. Conclusion: Ultrasound measurement of endometrial thickness is not sufficient to increase effectiveness of endometrial pathology diagnosis in women with abnormal peri- and postmenopausal bleeding.

Keywords

Endometrial NeoplasmsEndometrial Hyperplasia

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