Особливості стану імунної системи у пацієнток з функціональними кістами яєчників

The state of the immune system in patients with functional ovarian cysts DOI: https://doi.org/10.34287/MMT.4(55).2022.5Abstract Conducting a qualitative and comprehensive examination of patients with functional ovarian cysts is fundamentally necessary to understand the treatment strategy of this pathological state. The objective of the work was to study the features of immune disorders in patients of reproductive age with functional ovarian cysts. Methods. 50 patients of reproductive age with functional ovarian cysts were examined. General clinical, gynecological, ultrasound examination of the pelvic organs, a study of the state of the immune system were carried out. Results. In 70% of patients chronic inflammatory processes of the pelvic organs were detected. The findings revealed varying degrees of immune system disorders in women with ovarian cysts with different parity. In nulliparous and women who gave birth violations of cell immunity of the I degree were revealed, in the group with infertility - II degree. In the group of patients who gave birth and with infertility, the III degree of disorders of humoral immunity was diagnosed, and in nulliparous women - II degree. Conclusion. Determining the degree of disorders of the immune system already at the prehospital stage will allow individualizing the choice and dosing regimen of immunomodulatory drugs as part of the complex therapy of functional ovarian cysts. References - Zvarych, LI, Lutsenko, NS, Shapoval, OS et al. The frequency of functional ovarian cysts in women of reproductive age in the structure of gynecological pathology. Modern medical technologies. 2015; 2 – 3: 79 – 83. - Arora, Lt Col Devendra, Bhattacharyya, Col TK, Kathpalia, Lt Col SK et al. Acute abdomen in gynaecological. Practice MJAFI. 2005; 61: 66 – 70. - Shapoval, OS. Distribution of benign diseases of the pelvic organs in young women Actual and issues of medical science and practice. 2015; 82 (1): 112 - 120. - Shapoval, OS. Problematic issues of rehabilitation of patients of reproductive age after surgical treatment of tumor-like formations of the ovaries. Bulletin of Vinnytsia National Medical University. 2017; 1, part 2 (21): 306 – 309. - Trigg, BG, Kerndt, PR, Aynalem, G. Sexually transmitted infections and pelvic inflammatory disease in women. Med. Clin. North Am. 2008; 92 (5): 1083 – 1113. - Vovk, IB, Gorban, NE, Stamboli, LV. Features of the immunological status of women with retention ovarian cysts against the background of viral-bacterial infection of the genitals. Pediatrics, obstetrics and gynecology. 2013; 1: 84 – 87. - Shapoval, OS, Vorontsova, LL. The state of functional and metabolic activity of phagocytes in women of reproductive age with tumor-like ovarian formations. Laboratory diagnostics. Eastern Europe. 2015; 2 (14): 64 – 70. - Shapoval, OS. Strategy of anti-inflammatory therapy in patients with benign tumor-like formations of the ovaries. Modern medical technologies. 2017; 3 (34): 24 – 28. - Morozova, NA, Yakovleva, EB, Zheleznaya AA et al. Bacterial microflora of the urogenental tract and evaluation of antibacterial treatment in women with infertility. Women's health. 2015; 10 (106): 168 – 170. - Podolsky, VlV, Podolsky, VV. Treatment of changes in the microbiocenosis of urogenital organs in women with impaired autonomic homeostasis and changes in reproductive health. Women's health. – 2015; 10 (106): 125 – 128. - Putovski, L. Modern approaches to prophilactics of complications of inflammatory diseases of the organs of the small pelvis. Medical aspects of women's health. 2010; 4: 35. - Kvitka, NV, Goryunova GI, Peremot, SD. Andinfections in inflammatory diseases of the female genital organs. Transport Medicine of Ukraine. 2009; 3: 35 – 37. - Shapoval, OS, Vorontsova, LL. The state of the cellular and humoral links of the immune system in women of reproductive age with ovarian neoplasms. Pathology. 2014; 3 (32): 83 – 87. - Shapoval, OS, Vorontsova LL. Pathogenetic substantiation of medical immunocorrection in parous women with tumor-like formations. International Journal of Pediatrics, Obstetrics and Gynecology. 2016; 2 (9): 91 – 95. - Ostapenko, OI, Kvashenko, VP, Akimova IK. Influence of probiotics on the level of immunoglobulin A in women with impaired vaginal biocenosis. Women`s Health. 2017; 1 (117): 85 – 88. - Gnatko, OP, Skuryatina NG. Features of immuno-hormonal and microbiological status in women with different morphological forms of endometrial polyps. Tavrichesky medical and biological vestnik. 2012; 2 (15): 60 – 63. - Shapoval, OS, Vorontsova LL. Pathogenetic substantiation of medical immunorrection in parous women with endometriosis cysts of the ovaries. Women`s Health. 2017; 1 (117): 81 – 84. - Mancini, G, Carbonare, A, Henemans, J. Immunochemical quantitation of antigens by single radial diffusion. Immunochemistry. 1965; 2: 235. - Zemskov AM, Zemskov VM, Chereshnev VA. et al. Guidelines on Clinical Immunology for Clinical Physicians. Moscow:Triada-X, 2011. – 288 p. - Vovk, IB. Kornatskaya, AG, Lisyana, TO. Features of aerobic and anaerobic microflora in women with hyperproliferative diseases of the uterus and endometrium. Women`s Health. 2016; 2 (108): 102 – 106. Downloads Published How to Cite Issue Section License The work is provided under the terms of the Public Offer and of Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). This license allows an unlimited number of persons to reproduce and share the Licensed Material in all media and formats. Any use of the Licensed Material shall contain an identification of its Creator(s) and must be for non-commercial purposes only.