New 2,5-disubstituted benzimidazole derivatives, are gonadotropin releasing hormone antagonists useful e.g. for treating endometriosis, breast or prostate cancer or precocious puberty
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Novel 2,5-disubstituted benzimidazole derivatives act as GnRH antagonists and are useful for treating endometriosis, breast or prostate cancer, and precocious puberty.
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Abstract
The invention concerns novel benzimidazole derivatives of formula (I), wherein: A, Y, R1, R2, R3 and R4 represent diverse variable groups. Said products have a GnRH (Gonadotropin-Releasing Hormone) antagonist activity. The invention also concerns pharmaceutical compositions containing said products for preparing a medicine.
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- europepmc
- last seen: 2026-10-12T06:17:10.165071+00:00