[Morphologic features of the structure of the major duodenal papilla in healthy subjects and pathology of the biliopancreatic region]

The major duodenal papilla (MDP) was studied morphologically on the section material from 57 cases of diseases of the biliopancreatic area and from 60 other diseases. Two types of the structure of folds-valves of MDP mucosa were found to correspond to two main variants of fusion of the common bile duct and pancreatic duct. In the presence of a common channel of MDP (73%) the valves are arranged in 3 or 4 layers and each valve consists of 3 cusps. In cholelithiasis, chronic pancreatitis, and cholecystopancreatitis, signs of chronic inflammation in the MDP wall were found in all the cases and hyperplastic changes in half of the cases. In 7 observations of cholelithiasis, a close correlation between the development of MDP stenosis and the degree of adenomyosis and papillary outgrowths of the mucous membrane was established.