Case Characteristics, Clinical Data, and Outcomes of Hospitalized COVID-19 Patients in Qom Province, Iran: A Prospective Cohort Study

Background: The outbreak of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) dates back to December 2019 in China. Iran has been one of the most virus inflicted countries of all in which the first case of the disease was declared on 19th February, 2020 in Qom city. The aim of this study was to report demographics, signs and symptoms, laboratory findings, therapeutic approaches, and outcomes.Methods: This observational cohort study was performed from 20th February 2020 to 20th July 2020. All patients were admitted due to WHO, CDC, and Iran’s National Guidelines. Their information was recorded in their medical files. Multivariable analysis was performed to assess demographics, signs and symptoms, paraclinical data, treatments, outcomes of disease, and finding the risk factors of death subject to COVID-19.Findings: Of all 2468 participants, the mean age was 57.9±17.6 years and 56.8% of patients were male. The most significant comorbidities were seen among those who have Hypertension and Diabetes Mellitus. Cough, Dyspnea, and Fever were the most frequent symptoms. 92.3% of patients received supplementary oxygen, 14.42% were admitted to ICU, and 17.2% died in hospital. The significant risk factors of death related to COVID-19 were ageing, male gender, HTN, CHF, CVA, CKD, increasing ESR, PT, WBC, liver function tests, and decreasing Oxygen saturation.Interpretation: Incontinent results in the case of COVID-19 outcomes and death-related risk factors attribute to marked differences in demographics and health care systems. The patients with hazardous risk factors must be detected urgently and monitored closely to save more lives.Funding Statement: There was no source of funding, dedicated to this study.Declaration of Interests: None to declare.Ethics Approval Statement: The Qom University of medical sciences ethics committee (IR.MUQ.REC.1399.013) approved this cohort study.