Therapeutic effect of magnesium sulfate injection in the treatment of refractory nephriticcolic during pregnancy

Objective To evaluate the therapeutic efficacy of using magnesium sulfate injection in the treatment of refractory nephriticcolic due to ureteric calculi during pregnancy.Methods 23 cases of pregnant women complicated with refractory nephriticcolic due to ureteric calculi failed to respond to progesterone injection were randomly divided into 2 groups:observe group(magnesium sulfate injection used by transfusion)and control group(raceanisodamine used by transfusion).The analgesic effect and recurrent rate of nephriticcolic were observed between 2 groups.Results The total effective rate of observe group and control group were 84.6%and 40.0%respectively.The recurrent rate of nephriccolic was 16.7%in observe group and 62.5%in control group.Via x2 test,there were significant differences between 2 groups statistically in both the total effective rate and the recurrent rate of nephriccolic(P0.05).3 cases of frequent recurrent nephriticcolic with obstructive renal hydronephrosis were relieved by placing double-J-catheter.Conclusion In the treatment of refractory nephriticcolic due to ureteric calculi in pregnancy,magnesium sulfate injection possesses a better analgesic effect and less sideeffects than raceanisodamine injection and progesterone injection.