The efficacy of triptorelin or mifepristone for endometriosis after surgery

Objective To explore the clinical efficacy of triptorelin or mifepristone for endometriosis after surgery.Methods 120 patients with endometriosis who had been hospitalized during the period of August 2007 to October 2011 were randomly assigned to receive triptorelin ( 40 patients,group A ),mifepristone ( 40 patients,group B ),or conventional therapy ( 40 patients,group C ) for six months after surgery.The efficacy was observed.Results Dysmenorrhea and menorrhagia were relieved at different degrees in groups A and B.The effectiveness rate was 97.5％ in group A and 95％ in group B,which was higher than that in group C ( 75％ ).The rate of abnormal vaginal hemorrhage was significantly lower in group A ( 5％ ) than in group B ( 22.5％ ) and group C ( 45％ ),with a significant difference ( P＜0.05 ).Conclusions Surgery is the major therapy for endometriosis.Postoperative uses of triptorelin or mifepristone can evidently improve symptoms of the disorder.Triptorelin can be used as th medication of first choice for consolidation treatment due to better efficacy and fewer adverse reactions. Key words: Endometriosis; Triptorelin; Efficacy