Clinical research on the laparoscopic surgery combined with low-dose mifepristone in treatment of endometriosis

Objective To evaluate the clinical efficacy of laparoscopic surgery combined with low-dose mifepristone treatment of endometriosis. Methods 66 patients with endometriosis in our hospital were randomly divided into A group,B group,C group.A group was given laparoscopic surgery mifepristone treatment,and B group was given gestrinone capsule treatment,and C group wasn't given any secondary therapy.The recurrence rate within 1 year,response rate,pregnancy,menstruation and ovulation recovery time of three groups were compared. Results There was no statistically significant difference in response rates of three groups(P0.05),and there were significant differences in relapse rate and pregnancy rate(P 0.05).The recurrence rate of A group was significantly lower than that of group B and group C,and the pregnancy rate was higher than that of group B and group C, and there was more significant different(P 0.05).The recovery time of menstruation and ovulation recovery time in A group and group C were significantly shorter than those of group B,and the differences were statistically significant(P 0.05).Conclusion Laparoscopic surgery combined with low-dose mifepristone short-term therapy for endometriosis can help short recovery time of menstruation and ovulation,improve the pregnancy rate,and reduce the relapse rate. It's significant clinical efficacy,worthy of clinical application.