Клинико-анамнестическая характеристика и цитокиновый статус пациенток с генитальным эндометриозом

We performed analysis of history of 120 cases of endometriosis. Clinical forms of endometriosis and level of cytokines including interleukin IL-1, IL-8, tumor necrosis factor (TNF)-alpha, interferon (IFN)-alpha, interferon (IFN)-gamma were determine. Control group was consists of 100 healthy women. Adenomyosis was veri.cated in 85,8 % cases, tuboovarian endometriosis in 5,8 % patients, tuboovarian endometriosis and adenomyosis in 8,4 % women. Genital endometriosis was associated with urogenital anomalies in 3,3 % cases. Several cytokines including interleukin IL-8, tumor necrosis factor (TNF)-alpha, and interferon (IFN)-gamma were increased in the peripheral blood of women with endometriosis. Those cytokines may be involved in macrophage activation, inflammatory change and enhanced proliferation and angiogenesis.