Ovaries of different disease progression and the relationship between the ovarian malignant tumor research to the state of survival

In: Journal of clinical and experimental medicine · 2015 · W2367671064
article OA: closed CC0
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Abstract

Objective To explore the ovaries different syndrome( endometriosis,EMs) progression and the relationship between the ovarian malignant tumor and survival conditions. Methods A retrospective analysis of our hospital between January 2008 and January 2010 was performed. 80 patients with primary ovarian tumors were included as the research object. According to whether or not endometriosis cancerization,80 cases of patients were divided into endometriosis malignant transformation group( 22 cases,observation group) and non-endometriosis malignant transformation group( 58 cases,control group). The clinical feature and living conditions of two groups were comparatively studied. Results There was significant difference between onset ages,clinical symptoms,CA125 values,FIGO stage,tumor diameter,histological classification of two groups( P 0. 05),while no significant difference were found between chemotherapy regimens,cycles of chemotherapy( P 0. 05). 5-year survival rate of endometriosis malignant transformation group was significantly higher that of non-endometriosis malignant transformation group( P 0. 05). COX multi-factor analysis results show that the ovaries of different disease progression,FIGO staging,and histological classification are independent risk factors affecting the prognosis. Conclusion Different disease progression in the ovary is a risk factor for ovarian malignant tumors. Different disease progression in patients with ovary may have better prognosis,but should attach great importance to trigger the factors associated with malignant transformation,to combine prevention and improve the prognosis of patients.

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endometriosis

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