Clinical Usefulness of Determination of CA 125 Levels in the Serum and Menstrual Blood

K. Takahashi, Kentaro Takahashi, Takahashi K, H Nagata, Nagata H, Hiroko Nagata, Satoshi Kijima, Kijima S, S Kijima, Masuo Kusakari, Kusakari M, M Kusakari, T Shirai, Shirai T, Takaaki Shirai, Kazuo Yoshino, Yoshino K, K. Yoshino, M Kitao, Manabu Kitao, Kitao M
Gynecologic and obstetric investigation · 2010 · vol. 26(1) , pp. 63–65 · doi:10.1159/000293674 · PMID:3169631 · W2036043129
article OA: closed CC0 ⤵ 6 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This study found elevated serum CA 125 levels in women with endometriosis, particularly adenomyosis, and proposes menstrual blood CA 125 measurement for distinguishing adenomyosis and assessing endometriosis.

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Abstract

We measured CA 125 levels in sera and menstrual blood of subjects with a normal ovulatory cycle and in those with endometriosis. Serum CA 125 levels were higher in the latter, in each phase of the menstrual cycle. The CA 125 levels in patients with endometriosis, particularly those with adenomyosis, tend to be higher than in those with a normal ovulatory cycle. We propose that measurement of CA 125 in the menstrual blood may be able to help distinguishing adenomyosis from myoma uteri and may also help in assessing clinical endometriosis.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Antigens, Tumor-Associated, Carbohydrate Endometriosis Menstruation Antigens, Tumor-Associated, Carbohydrate Endometriosis Female Humans Ovulation Reference Values

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (6)

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europepmc
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License: CC0 · commercial use OK