[Advances in Post-translational Modifications and Endometriosis].

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AI-generated summary by claude@2026-06, 2026-06-10

This review examines how protein post-translational modifications like phosphorylation and acetylation are implicated in the development and potential treatment of endometriosis.

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AI-generated deep summary by claude@2026-06, 2026-06-10

This paper provides a research overview on how post-translational modifications are implicated in endometriosis, covering multiple modification types and the molecular mechanisms reported in the literature. It summarizes findings from studies examining how altered protein modification states relate to key endometriosis-associated processes, such as disease progression and dysregulated cellular functions. A major limitation is that, as an advances/review-type article, it synthesizes existing evidence rather than presenting new experimental results, so conclusions depend on the quality and scope of included studies. This paper is centrally about endometriosis — it focuses on advances in post-translational modifications and their mechanistic roles in the condition.

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Abstract

Proteins exert their roles in life activities via post-translational modifications(PTMs),which include phosphorylation,acetylation,ubiquitination,glycosylation,and methylation.These modifications can change the functions of proteins and play key roles in a variety of diseases.Endometriosis is a common disease in women of childbearing age,although its molecular mechanisms remain unclear.Recent studies have shown that PTMs may be involved in the pathogenesis of endometriosis.Here we review the roles of PTMs in the occurrence and development of endometriosis and the potential medical treatments.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Protein Processing, Post-Translational Acetylation Endometriosis Female Glycosylation Humans Phosphorylation Ubiquitination

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europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:25:00.839251+00:00
License: CC0 · commercial use OK