Adjuncts for ovarian stimulation: when do we adopt “orphan indications” for approved drugs?

David R. Meldrum, R. Jeffrey Chang, Dominique de Ziegler, William B. Schoolcraft, Richard T. Scott, António Pellicer
In: Fertility and Sterility · 2009 · vol. 92(1) , pp. 13–18 · doi:10.1016/j.fertnstert.2009.03.081 · PMID:19423104 · W2152736272
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⚙ AI-generated summary by qwen3.7-flash, 2026-09-09 ⓘ

The authors evaluate the efficacy and safety of approved drugs used as adjuncts for ovarian stimulation under orphan indications, providing recommendations to expand their clinical utility.

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Abstract

Several drugs, shown to be safe for other uses, have proven to be highly effective adjuncts for ovarian stimulation. The authors evaluate these "orphan" indications and make recommendations so that more patients will benefit from their use.

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