Effect of anterior vaginal wall prolapse repair by modified transvaginal mesh surgery: a retrospective cohort study

Abstract Objective To explore clinical outcomes and complications of modified Transvaginal mesh (M-TVM) for advanced anterior vaginal wall prolapse in 1 year follow up. Methods 574 patients underwent TVM surgeries from 2019 to 2020 were collected and divided into traditional TVM group and M-TVM group according to different surgeries, all preoperative and postoperative data was obtained and compared between the two groups. Results 285 women were involved eventually, including 181 for TVM group and 104 for M-TVM group. No significant differences of general conditions were found between these two groups. During long-term follow up period, patients in TVM group were more likely to suffer pelvic pain than M-TVM group after surgery (P=0.046). Meshes placed with M-TVM protocol (4.5±0.69 cm) seemed much wider than meshes placed with TVM (3.0±0.91cm). Surgeries can significantly change a prolapse to point Aa and Ba on POP-Q compared to preoperative data. M-TVM procedures may significant change point C and D after surgery compared to TVM surgery(P＜0.001). Conclusion M-TVM is a commendable procedure that can significant correct anterior prolapse with mesh extended wider, and also supply stable apical support at the same time.