Role of endometriosis in infertility and embryonic loss: more than anatomical reasons

The association between endometriosis and infertility is widely recognized, but several studies demonstrate that endometriosis also affects pregnancy rates in different ways other than anatomical distortion of internal reproductive organs; however the evoking mechanisms are complex. In mild to advanced stages of disease, peritoneal adhesions, tubal obstruction, destruction of ovarian tissue or distortion of the uterine wall are evident originating factors of infertility or miscarriage.