Analysis of clinical factors in endometriosis of the abdominal wall

This retrospective study analyzed 228 surgically confirmed cases of abdominal wall endometriosis treated at Changzhou Second Hospital from 2013–2022, comparing clinical factors across lesion complexity (solitary vs complex) and across invasion depth (fascial, rectus abdominis, peritoneal), with outcomes including BMI, CA125, latency, lesion size, operative time, bleeding, and postoperative hospital stay. The authors found that complex cases were associated with lower BMI, longer operations, more bleeding, and longer postoperative hospitalization, and that deeper (peritoneal) lesions had longer latency, larger maximum diameter, higher CA125, and worse perioperative metrics. Imaging results showed abdominal wall MRI was more accurate than ultrasound for typing lesion depth, and the paper reports using combined ultrasound and CA125 with an ROC cut-off for distinguishing peritoneal versus non-peritoneal involvement, while noting limitations of a single-center retrospective design and that not all patients had MRI. This paper is centrally about endometriosis — specifically abdominal wall endometriosis and how invasion depth and imaging/CA125 relate to clinical and surgical features.

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