Possible Response of Paroxysmal Cold Hemoglobinuria to Danazol

In: Annals of Internal Medicine · 1987 · vol. 106(4) , pp. 635 · doi:10.7326/0003-4819-106-4-635_1 · PMID:3826969 · W1997388273
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A patient with paroxysmal cold hemoglobinuria achieved remission of their disease after starting danazol therapy.

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Abstract

Letters and Corrections1 April 1987Possible Response of Paroxysmal Cold Hemoglobinuria to DanazolMORIE A. GERTZ, M.D.MORIE A. GERTZ, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-106-4-635_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: I report the case of a patient with paroxysmal cold hemoglobinuria whose disease went into remission after the initiation of danazol therapy.A 58-year-old man developed the abrupt onset of dark red urine on 10 June 1986. He was hospitalized for evaluation of anemia. His hemoglobin level consistently fell below 7 g/dL and over the next 30 days he required a total of 28 units of packed erythrocytes. A 1-month trial of prednisone at 1 mg/kg body weight · d did not reduce his transfusion requirement and was discontinued. Physical examination was normal except for pallor and...References1. AHNHARRINGTONMYLVAGANAMAYUBPALL YWRJL. Danazol therapy for autoimmune hemolytic anemia. Ann Intern Med. 1985;102:298-301. LinkGoogle Scholar2. MACKENZIE G. Paroxysmal hemoglobinuria: a review. Medicine. 1929;8:159-91. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Mayo Clinic Rochester, MN 55905 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 April 1987Volume 106, Issue 4Page: 635-635KeywordsAnemiaBody weightHemoglobinUrine Issue Published: 1 April 1987 PDF DownloadLoading ...

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