Solitary rectal ulcer syndrome: a radiologic diagnosis?

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Barium enemas may reveal thickened, edematous valves of Houston or a submucosal mass in solitary rectal ulcer syndrome, especially in patients with rectal bleeding.

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This study retrospectively assembled eight pathologically proven cases of solitary rectal ulcer syndrome (SRUS) from 1981–1983 in which barium enema examinations were performed, and evaluated how the findings were originally interpreted versus a blinded rereading after gaining radiologic experience with SRUS. The authors found that original radiology reports often missed SRUS or did not suggest it specifically, although four cases were reinterpreted as still normal while the other four showed thickened, edematous valves of Houston or a submucosal mass adjacent to the anal verge; SRUS was suggested in all four reread abnormal cases with one false-positive due to rectal stricture in a patient with endometriosis. The main limitation is the small sample size (eight SRUS cases) and the retrospective design using existing radiologic reports and rereading. This paper does not directly study endometriosis or adenomyosis; relevance to endometriosis: endometriosis is mentioned only in the context of a false-positive diagnosis (a patient with rectal stricture), though the paper’s main focus is SRUS radiologic diagnosis.

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Abstract

The solitary rectal ulcer syndrome (SRUS) is an uncommon condition in which a solitary area of discrete ulceration is typically found on the anterior wall of the rectum. Between 1981 and 1983, we collected 8 pathologically proven cases of SRUS in which barium enema examinations had been performed (7 double-contrast, 1 single-contrast). Seven patients had rectal bleeding. On the original x-ray report, 4 cases were thought to be normal, but the pathologic tissue had been removed endoscopically in 2 of these cases prior to the radiologic study. The other 4 cases were thought to be abnormal, although the specific diagnosis of SRUS was not suggested in any case. In a blinded rereading of these 8 cases randomly interspersed with 29 other non-SRUS cases, however, the films were interpreted in light of recent radiologic experience with this condition. The same 4 cases were still thought to be normal. In the remaining 4 cases, barium enemas revealed thickened, edematous valves of Houston (3 cases) and a submucosal mass adjacent to the anal verge (1 case). The diagnosis of SRUS was suggested in all 4 cases with only 1 false-positive diagnosis due to a rectal stricture in a patient with endometriosis. Although barium enemas may be normal in patients with SRUS, the presence of thickened, edematous valves of Houston, particularly in a young patient with rectal bleeding, should suggest this condition.
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Abstract

The solitary rectal ulcer syndrome (SRUS) is an uncommon condition in which a solitary area of discrete ulceration is typically found on the anterior wall of the rectum. Between 1981 and 1983, we collected 8 pathologically proven cases of SRUS in which barium enema examinations had been performed (7 double-contrast, 1 single-contrast). Seven patients had rectal bleeding. On the original x-ray report, 4 cases were thought to be normal, but the pathologic tissue had been removed endoscopically in 2 of these cases prior to the radiologic study. The other 4 cases were thought to be abnormal, although the specific diagnosis of SRUS was not suggested in any case. In a blinded rereading of these 8 cases randomly interspersed with 29 other non-SRUS cases, however, the films were interpreted in light of recent radiologic experience with this condition. The same 4 cases were still thought to be normal. In the remaining 4 cases, barium enemas revealed thickened, edematous valves of Houston (3 cases) and a submucosal mass adjacent to the anal verge (1 case). The diagnosis of SRUS was suggested in all 4 cases with only 1 false-positive diagnosis due to a rectal stricture in a patient with endometriosis. Although barium enemas may be normal in patients with SRUS, the presence of thickened, edematous valves of Houston, particularly in a young patient with rectal bleeding, should suggest this condition. Similar content being viewed by others

References

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Condition tags

endometriosis

MeSH descriptors

Rectal Diseases Adult Aged Biopsy Female Humans Male Middle Aged Radiography Rectal Diseases Rectal Diseases Sigmoidoscopy Ulcer Ulcer Ulcer

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