Keep Your Bladder Small: Micturition Dysfunction in Deep Pelvic Endometriosis

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This paper investigates the relationship between deep pelvic endometriosis and micturition dysfunction, exploring how the condition affects bladder function.

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This editorial discusses how deep infiltrating endometriosis (DIE) can cause micturition dysfunction through several pathways, including direct bladder wall infiltration, indirect effects of chronic inflammation, and pelvic nerve involvement, leading to lower urinary tract symptoms such as dysuria, urgency, frequency, suprapubic pain, and sometimes hematuria with full-thickness invasion. It highlights that even without direct bladder nodule involvement, LUTS may occur via nerve effects or inflammation, and that symptoms can worsen cyclically around menstruation. The paper also describes postoperative de novo voiding dysfunction after DIE surgery—reported as occurring in up to 30%—with mechanisms including extent of dissection and neural damage, and notes a limitation that it is largely based on cited literature rather than new patient data. This paper is centrally about endometriosis — it focuses specifically on micturition dysfunction and urinary tract complications in deep pelvic endometriosis, including bladder involvement and postoperative voiding problems.

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Results

in reduced urinary frequency over time. This gradu- ally increases bladder capacity, with secondary impairment of bladder elasticity and contractility (myogenic damage). Resulting postvoid residual volumes increase over time and subsequently deteriorate bladder contractility even more. These symptoms can appear up to 7 years after DIE surgery [3]. Follow up of patients after DIE surgery should not focus only on disease recurrence but also on voiding function. Physicians should pay attention to reduced urinary fre - quency and weak urinary stream. Post-void residual urine should be controlled regularly. In case of higher post-void values, intermittent self-catheterization must be started early enough, before bladder myogenic damage becomes irreversible. As awareness of endometriosis grows, so must recogni- tion of its impact on urinary tract (dys)function. Recognizing micturition problems as part of a comprehensive endometri- osis care strategy is vital for improving patient outcomes. By emphasizing early diagnosis, recognizing de novo postopera- tive micturition dysfunction, multidisciplinary approach, and targeted therapies, we can ensure the improvement of quality of life in women with DIE. * Rok Šumak [email protected] 1 Department of General Gynecology and Gynecological Urology, Clinic for Gynecology and Perinatology, University Medical Centre Maribor, Maribor, Slovenia 732 International Urogynecology Journal (2025) 36:731–732

References

1. Gabriel I, Vitonis AF, Missmer SA, Fadayomi A, DiVasta AD, Terry KL, et al. Association between endometriosis and lower urinary tract symptoms. Fertil Steril. 2022;117(4):822–30. 2. Dubernard G, Rouzier R, David-Montefiore E, Bazot M, Daraï E. Urinary complications after surgery for posterior deep infil- trating endometriosis are related to the extent of dissection and to uterosacral ligaments resection. J Minim Invasive Gynecol. 2008;15(2):235–40. 3. Possover M. Pathophysiologic explanation for bladder reten- tion in patients after laparoscopic surgery for deeply infiltrat- ing rectovaginal and/or parametric endometriosis. Fertil Steril. 2014;101(3):754–8. Publisher’s Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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endometriosis

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europepmc
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pubmed
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