Reproductive Health of Women with the Combined Pathology of Uterus and Mammary Glands

О. А. Полюлях
In: Family medicine · 2019 · pp. 99–101 · doi:10.30841/2307-5112.2.2019.175663 · W2973964433
article OA: diamond CC0
🔓 Open OA copy Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-09 ⓘ

This study developed and implemented a diagnostic and prophylactic treatment algorithm for women with combined uterine and mammary gland pathologies, significantly reducing reproductive losses and obstetric/perinatal complications.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-07, 2026-07-09 · read from full text ⓘ

The study examined reproductive function and pregnancy outcomes in women with combined pathology affecting the uterus and mammary glands, focusing on sterility pathogenesis and rates of obstetric and perinatal complications. It included 90 women with diffuse mammary gland dysplasia (with subgroups based on accompanying genital pathology) and a broader complex evaluation of 210 women, using auxiliary reproductive technologies and multidisciplinary clinical-laboratory functional assessment (including ultrasonography, Doppler, cardiotocography, morphology, endocrine and biochemical tests). Using a diagnostic and treatment-and-prophylactic algorithm, the authors reported reductions in multiple outcomes, including spontaneous abortion (4.5%), placental dysfunction (14.3%), preeclampsia (7.8%), fetal distress (7.8%), neonatal asphyxia (up to 14.8% for average degree), and perinatal losses (3.5%), among others. This paper is centrally about adenomyosis and related uterine pathology in the context of mammary dysplasia’s combined reproductive impacts.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

The objective: depression of disturbances of reproductive function and gestational complications at women with combined pathology of uterus and mammary glands on the basis of studying of new aspects of pathogenesis of sterility and development of obstetric and perinatal pathology, and also improvement and introduction of algorithm of diagnostic and treatment-and-prophylactic actions depending on options of the combined pathology of uterus and mammary glands.Materials and methods. Sterility treatment at all patients at 1 stage was carried out by use of auxiliary reproductive technologies. 1 group was made by 90 women with diffuse diplasya of mammary glands. Three subgroups were distinguished from them taking into account existence of accompanying genital pathology. At the 2nd stage of researches by us it was carried out complex clinical-laboratory and functional inspection 210 women who depending on existence of the combined pathology of uterus and mammary glands were divided into groups and subgroups. In complex of the conducted researches were included clinical, ekhografical, dopplerometrical, cardiotocografical, morphological, endocrinological, biochemical and statistical.Results. Use of algorithm of diagnostic and treatmentand-prophylactic actions allows to reduce the frequency of spontaneous abortion by 4.5%; premature births – for 3.3%; placental dysfunction – for 14.3%; preeclampsias – for 7.8%; anomalies of patrimonial activity – for 11.1%; fetus distress – for 7.8%; the cesaraen sections – for 10.0%; asphyxias of newborns of average degree – for 14.8%; the serious – for 7.3%; post-hypoxemic encephalopathy – for 7.3%; realization of fetal becoming infected – for 6.8% and perinatal losses – for 3.5% respectively.Conclusion. Use of advanced algorithm of treatment-and-prophylactic actions at women with the combined pathology of uterus and mammary glands allows to reduce significantly frequency not reproductive losses, but also obstetric and perinatal complications that is the solution of an important problem of modern obstetrics.
Full text 4,380 characters · extracted from oa-doi-fallback · 3 sections · click to expand

Abstract

The objective: depression of disturbances of reproductive function and gestational complications at women with combined pathology of uterus and mammary glands on the basis of studying of new aspects of pathogenesis of sterility and development of obstetric and perinatal pathology, and also improvement and introduction of algorithm of diagnostic and treatment-and-prophylactic actions depending on options of the combined pathology of uterus and mammary glands.

Materials

and methods. Sterility treatment at all patients at 1 stage was carried out by use of auxiliary reproductive technologies. 1 group was made by 90 women with diffuse diplasya of mammary glands. Three subgroups were distinguished from them taking into account existence of accompanying genital pathology. At the 2nd stage of researches by us it was carried out complex clinical-laboratory and functional inspection 210 women who depending on existence of the combined pathology of uterus and mammary glands were divided into groups and subgroups. In complex of the conducted researches were included clinical, ekhografical, dopplerometrical, cardiotocografical, morphological, endocrinological, biochemical and statistical. Results. Use of algorithm of diagnostic and treatmentand-prophylactic actions allows to reduce the frequency of spontaneous abortion by 4.5%; premature births – for 3.3%; placental dysfunction – for 14.3%; preeclampsias – for 7.8%; anomalies of patrimonial activity – for 11.1%; fetus distress – for 7.8%; the cesaraen sections – for 10.0%; asphyxias of newborns of average degree – for 14.8%; the serious – for 7.3%; post-hypoxemic encephalopathy – for 7.3%; realization of fetal becoming infected – for 6.8% and perinatal losses – for 3.5% respectively. Conclusion. Use of advanced algorithm of treatment-and-prophylactic actions at women with the combined pathology of uterus and mammary glands allows to reduce significantly frequency not reproductive losses, but also obstetric and perinatal complications that is the solution of an important problem of modern obstetrics.##plugins.themes.bootstrap3.article.details## This work is licensed under a Creative Commons Attribution 4.0 International License. Authors retain the copyright and grant the journal the first publication of original scientific articles under the Creative Commons Attribution 4.0 International License, which allows others to distribute work with acknowledgment of authorship and first publication in this journal.

References

Запорожан В.М. Нові технології у хірургічному лікуванні глибокого інфільтративного і поверхневого перитонеального ендометріозу / В.М. Запорожан, І.З. Гладчук, Н.М. Рожковська [та ін.] // Репродуктивная эндокринология. – 2014. – № 2 (16). – С. 7–9. Захаренко Н.Ф. До питання комплексної терапії ендометріозу / Н.Ф. Захаренко, Н.В. Коваленко, І.П. Маноляк // Репродуктивна ендокринологія. – 2015. – № 3 (23). – С. 28–33. Vandermeulen L. Guiding histological assessment of uterine lesions using 3D in vitro ultrasonography and stereotaxis / L. Vandermeulen, A. Cornelis, C. Kjaergaard Rasmussen [et al.] // Facts Views Vis Obgyn. – 2017. – № 9 (2). – P. 77–84. Ferenczy A. Pathophysiology of uterine patology / A. Ferenczy // Hum Reprod Update. – 2018. – Vol. 4. – P. 312–322. Benson R.C. Dysplasia of mammary glands and adenomyosis: a reappraisal of symptomatology / R.C. Benson, V.D. Sneeden // Am J. Obstet GynecoI. – 2017. – Vol. 76. – P. 1044–1057. Клинические рекомендации. Акушерство и гинекология / под ред. Г.М. Савельевой, В.Н. Серова, Г.Т. Сухих. – 4-е изд., перераб. и доп. – М.: ГЭОТАР-Медиа, 2015. – 1024 с. Акушерство та гінекологія: у 4-х т.: національний підручник за ред. акад. НАМН України, проф. В.М. Запорожана // В.М. Запорожан, В.К. Чайка, Л.Б. Маркін [та ін.]. – К.: ВСВ «Медицина», 2013. – 1032 с. Юзько О.М. Тактика допоміжних репродуктивних технологій на сучасному етапі // Практична медицина. – 2017. – № 2. – С. 46–52. Наказ МОЗ України від 02.11.2015 р. № 709 «Про затвердження та впровадження медико-технологічних документів зі стандартизації медичної допомоги при високому перинатальному ризику (Уніфікований клінічний протокол первинної, вторинної (спеціалізованої) медичної допомоги «Високий перинатальний ризик».

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (4)

References (5)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK